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PureTech Health Loss Widens; Expects Six Affiliates To Begin Earning

Wed, 24th Apr 2019 12:19

LONDON (Alliance News) - Biotechnology company PureTech Health PLC on Wednesday reported a slightly narrower annual loss despite a sharp rise in revenue.

In 2018, the US-based company, which develops medicines for dysfunctions in the brain-immune-gut axis, reported a pretax loss of USD68.4 million compared to USD70.7 million in 2017.

The company reported a sharp rise in revenue in 2018 to USD20.7 million from USD2.5 million the year before.

PureTech's administrative expenses increased 2.4% to USD47.4 million from USD46.3 million. The company's research & development expenses increased 7.9% to USD77.4 million from USD71.7 million.

In the year prior, PureTech booked a USD85.0 million gain on deconsolidation of its ownership in an affiliate, compared to USD41.7 million in 2018. The company saw a USD57.3 million gain on investments held at fair value. In 2018, the company reported a USD20.3 million loss on investments held at fair value.

"It has been an exhilarating year and we believe we are on the cusp of unlocking significant value for our shareholders. We are gratified by the excellent reception of our Internal R&D group, which has already secured partnerships with two major pharmaceutical companies, validating the science while enabling PureTech Health to retain most of the rights to the core platforms," said Chief Executive Daphne Zohar.

"We believe that six of our affiliates have the potential for monetisation over the next 12 to 18 months, and we are extremely excited by the post-period news about Gelesis' landmark FDA clearance last week, which is a testament to what our team has been able to accomplish by thinking differently about major health issues," added Zohar.

In 2018, PureTech's affiliates raised USD274 million.

Shares in PureTech Health were down 0.8% on Wednesday at 185.00 pence each.

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23 Mar 2023 07:24

US Royalty Pharma strikes deal with PureTech Health on KarXT royalties

(Sharecast News) - US-listed Royalty Pharma has acquired an interest in PureTech Health's royalty in Karuna Therapeutics' KarXT drug for up to $500m, with $100m in cash up front and up to $400m in additional payments contingent on the achievement of certain regulatory and commercial milestones.

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20 Mar 2023 16:01

PureTech Health says Karuna KArXT trial receives positive results

(Alliance News) - PureTech Health PLC on Monday said its founded entity, Karuna Therapeutics Inc announced its phase 3 EMERGENT-3 trial of KarXT in Schizophrenia has met its primary endpoint.

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28 Feb 2023 21:05

TRADING UPDATES: Eco Atlantic swings to loss; Curtis approves takeover

(Alliance News) - The following is a round-up of updates by London-listed companies, issued on Monday and not separately reported by Alliance News:

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14 Feb 2023 13:27

IN BRIEF: PureTech Health to start trials for anxiety, depression drug

PureTech Health PLC - clinical-stage biotherapeutics company - Says it will advance LYT-300 for the potential treatment of anxiety disorders and post-partum depression. A placebo-controlled, phase 2a, proof-of-concept, social anxiety clinical trial is expected to begin in the first half of 2023. Results are expected by the end of the year. An open-label, phase 2a, proof-of-concept clinical trial in women with post-partum depression is expected to begin in the second half of 2023.

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6 Jan 2023 18:31

PureTech's Alkili reports success in adolescent ADHD study

(Sharecast News) - Clinical-stage biotherapeutics investor PureTech Health announced on Friday today that its digital medicine company Akili, which it founded, announced topline results of the 'STARS-ADHD-Adolescents' label expansion study evaluating the efficacy and safety of 'EndeavorRx', or 'AKL-T01' in adolescents aged 13 to 17 with attention-deficit hyperactivity disorder (ADHD).

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6 Jan 2023 08:52

PureTech says ADHD treatment shows improved attentional functioning

(Alliance News) - PureTech Health PLC on Friday said the topline results for the pivotal trial of its EndeavorRx treatment showed "robust improvements in attention and broader clinical outcomes".

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23 Dec 2022 18:15

TRADING UPDATES: Fiinu teams with TransUnion; GRC wins pact

(Alliance News) - The following is a round-up of updates by London-listed companies, issued on Monday and not separately reported by Alliance News:

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9 Dec 2022 16:35

PureTech entity Sonde raises USD19.3 million in investment round

(Alliance News) - PureTech Health PLC on Friday said that its founded entity, Sonde Health Inc, has completed a Series B investment round for the development of its voice-based health monitoring technology.

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8 Dec 2022 10:15

PureTech founded entity Vor Bio first AML patient gets transplant

(Alliance News) - PureTech Health PLC on Thursday announced that its founded entity Vor Biopharma Inc has successfully transplanted its investigational trem-Cel into a patient with acute myeloid leukemia.

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30 Nov 2022 17:33

PureTech Health advances new therapeutic candidate to clinical studies

(Alliance News) - PureTech Health PLC on Wednesday said that it had advanced LYT-310, an oral form of cannabidiol (CBD) prodrug toward clinical studies.

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13 Oct 2022 10:14

LONDON BROKER RATINGS: Mondi and Smurfit Kappa raised, DS Smith cut

(Alliance News) - The following London-listed shares received analyst recommendations Thursday morning and Wednesday:

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13 Oct 2022 07:50

LONDON BRIEFING: Entain looks to World Cup; easyJet revenue improves

(Alliance News) - Stocks in London were called lower on Thursday as investors look ahead to an afternoon which may deliver the final nail in the coffin for hopes of a dovish tilt by the US Federal Reserve.

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11 Oct 2022 17:09

LONDON MARKET CLOSE: Stocks down; IMF warns "the worst is yet to come"

(Alliance News) - Stock prices in London closed lower on Tuesday, as storm clouds gathered over the global economic outlook, as UK fiscal policy also faces increasing scrutiny.

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11 Oct 2022 09:00

PureTech Health takeover talks with Nektar Therapeutics end

(Alliance News) - PureTech Health PLC on Tuesday said takeover talks with San Francisco-based biopharmaceutical company Nektar Therapeutics have been terminated.

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11 Oct 2022 08:46

LONDON MARKET OPEN: Stocks struggle again amid BoE bond market warning

(Alliance News) - Stock prices in London opened lower on Tuesday, while the pound was on the back foot as the Bank of England once again attempted to calm a tetchy, and now "stability" threatening, bond market.

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