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Pin to quick picksN4 Pharma Plc Share News (N4P)

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TRADING UPDATES: N4 Pharma hails "encouraging" siRNA research

Thu, 07th Dec 2023 18:28

(Alliance News) - The following is a round-up of updates by London-listed companies, issued on Thursday and not separately reported by Alliance News:

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Wentworth Resources PLC - Tanzania-focused natural gas production company - Etablissements Maurel & Prom SA, a Paris-based, energy industry-focused company, says it is moving closer to acquiring Wentworth. Explains that it has signed an agreement with the Tanzania Petroleum Development Corporation, which is structured as a 'call option' and allows Tanzania Petroleum to increase its ownership in the production interest by up to 20%. Wentworth has arranged for the Jersey Court to consider and possibly sanction the scheme at a hearing on December 19. Following this date, M&P will take ownership of Wentworth and acquire its 32% direct and indirect interest in Mnazi Bay. Subsequent to the closing of the Acquisition, M&P expects Tanzania Petroleum this call option, meaning that M&P will hold a 60% ownership in Mnazi Bay, and Tanzania Petroleum will hold 40%. M&P says the joint operating agreement will be changed to reflect these new partnership conditions. Adds that it will fund the acquisition with the GBP63 millio placed in escrow.

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N4 Pharma PLC - Derbyshire-based specialist pharmaceutical company focused on a delivery system for oncology, gene therapy and vaccines - Says that its work-to-date on its ongoing in vitro small interfering ribonucleic acid research, or siRNA, is "very encouraging", and shows that Nuvec has "considerable potential" to be able to knockdown two independent pathways leading to "more effective "cancer treatments. Explains that it has been investigating the ability of Nuvec nanoparticles to be loaded with, and deliver at the same time, two different siRNA known to inhibit relevant oncology targets. After confirming dual loading of Nuvec, N4 then tested the effect of BRD4 combined with EGFR and PLK1 combined with EGFR on knockdown and cell viability. Says that when when loaded together there was an interaction which resulted in a reduction in knockdown of EGFR receptor, though the reduction on cell viability was retained. It is now exploring varying the amount of each siRNA loaded on Nuvec, and also looking at how low the dose can be reduced to still achieve a functional cell inhibition endpoint. In terms of strategy moving forwards, says that that the precise combinations of siRNA, both in terms of target and concentration of siRNA, will vary depending in which cell type they are tested in.

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Software Circle PLC - Manchester-based printing and software company - Regarding the sale of Works Manchester Ltd, says that Works Manchester has filed a notice of intention to appoint administrators. This follows an earlier announcement in June, when Software said it had not received the first instalment of deferred consideration from Rymack Sign Solutions Ltd to buy Works Manchester. Further, due to reduced confidence of receiving payment of any deferred consideration from Rymack, the carrying value of the GBP2.81 million due under the sale and purchase agreement has been reduced to GBP350,000. Software is in the process of taking steps to recover the sums due, and says it will update the market again in due course. Adds that the Nettl Systems management team have been making arrangements with alternative suppliers so that continuity of supply is in place for products available through the Nettl Systems platform.

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Ecofin US Renewables Infrastructure Trust PLC - Investor in US renewable energy assets - Expects its Whirlwind Energy wind asset in in Floydada, Texas to reenergise in mid-December, after moving "significantly closer" to coming back online. Says that AEP, the owner of the Matador and Paducah substations, has now finished testing a new transmission line past Matador to Paducah. Adds that the first payment on its business interruption coverage has now been received and further payments are scheduled to follow, "substantially mitigating lost revenue". Meanwhile, the Ellis Road solar farm in Westminster, Massachusetts is back online, following a rodent infestation. Finally, says that progress continues to be made on a previously announced strategic review. Says there can be no certainty as to the outcome of the review or any asset sale process, nor whether any potential transaction or transactions arising could be successfully completed.

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By Holly Beveridge, Alliance News reporter

Comments and questions to newsroom@alliancenews.com

Copyright 2023 Alliance News Ltd. All Rights Reserved.

More News
7 Dec 2023 13:20

N4 Pharma posts optimistic Nuvec research update

(Sharecast News) - N4 Pharma, a specialist pharmaceutical company focused on developing the Nuvec delivery system for cancer treatments and vaccines, issued an optimistic update on its ongoing in-vitro siRNA research efforts on Thursday.

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1 Dec 2023 14:29

TRADING UPDATES: N4 launches investor hub; Capricorn production falls

(Alliance News) - The following is a round-up of trading updates by London-listed companies, issued on Wednesday, Thursday and Friday and not separately reported by Alliance News:

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28 Sep 2023 13:28

N4 Pharma picks up controlling interest in Nanogenics

(Sharecast News) - Pharmaceutical firm N4 Pharma announced the acquisition of a controlling interest in Nanogenics on Thursday.

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28 Sep 2023 10:20

N4 Pharma shares fall as places shares to fund Nanogenics stake buy

(Alliance News) - N4 Pharma PLC on Thursday said it bought a controlling interest in Nanogenics Ltd, a company with a lipid and peptide-based delivery system called Liptide.

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12 Sep 2023 13:43

N4 Pharma interim loss narrows slightly as business outreach ongoing

(Alliance News) - N4 Pharma PLC on Tuesday said its business outreach is ongoing as it continued to work on getting Nuvec, its delivery system for vaccines and cancer treatment, into clinic.

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25 Jul 2023 12:08

LONDON MARKET MIDDAY: Miners lift FTSE 100 as Fed meeting kicks off

(Alliance News) - Stock prices in London were largely higher at midday on Tuesday, with stimulus talks in China helping lift the mood, as attention turns to the US Federal Reserve which begins its two-day monetary policy meeting later.

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25 Jul 2023 10:12

N4 Pharma shares soar on further patent grant for Nuvec in US

(Alliance News) - N4 Pharma PLC on Tuesday saw its shares rise, as it celebrated a patent grant for Nuvec in the US.

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25 Jul 2023 10:04

AIM WINNERS & LOSERS: N4 Pharma shares jump on grant of US patent

(Alliance News) - The following stocks are the leading risers and fallers on AIM in London on Tuesday.

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27 Jun 2023 12:13

IN BRIEF: N4 Pharma expands Professor Yu partnership on grant award

N4 Pharma PLC - Derby, England-based pharmaceutical company focused on developing Nuvec, a delivery system for vaccines and cancer treatments - Says it will be supporting the University of Queensland as part of a recent grant award by the Australian Research Council. Professor Chengzhong Yu, senior group leader at the Australian Institute for Bioengineering & Nanotechnology, has been awarded an AUD402,115 grant - around GBP211,366 - to develop an improved nanoparticle delivery system that enhances the performance of messenger ribonucleic acid therapies.

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25 Apr 2023 16:19

TRADING UPDATES: Eckoh expects profit up; LXi REIT refinances facility

(Alliance News) - The following is a round-up of updates by London-listed companies, issued on Tuesday and not separately reported by Alliance News:

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25 Apr 2023 10:30

AIM WINNERS & LOSERS: FireAngel 2023 earnings below expectations

(Alliance News) - The following stocks are the leading risers and fallers on AIM in London on Tuesday.

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18 Apr 2023 14:20

TRADING UPDATES: Journeo extends contract; Biome completes fundraise

(Alliance News) - The following is a round-up of updates by London-listed companies, issued on Tuesday and not separately reported by Alliance News:

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18 Apr 2023 13:13

N4 Pharma reports progress with siRNA work

(Sharecast News) - N4 Pharma updated the market on its ongoing research work on gene-silencing technology siRNA on Tuesday.

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27 Mar 2023 15:50

UK earnings, trading statements calendar - next 7 days

Tuesday 28 March 
AG Barr PLCFull Year Results
Animalcare Group PLCFull Year Results
Bango PLCTrading Statement
Bellway PLCHalf Year Results
CPPGroup PLCFull Year Results
DigitalBox PLCFull Year Results
eEnergy Group PLCHalf Year Results
EKF Diagnostics Holdings PLCFull Year Results
Eleco PLCFull Year Results
Empresaria Group PLCFull Year Results
Flowtech Fluidpower PLCFull Year Results
Good Energy Group PLCFull Year Results
Impact Healthcare REIT PLCFull Year Results
John Wood Group PLCFull Year Results
Marlowe PLCTrading Statement
Mission Group PLCFull Year Results
Mortgage Advice Bureau Holdings PLCFull Year Results
Nanoco Group PLCHalf Year Results
Ocado Group PLCTrading Statement
Personal Group Holdings PLCFull Year Results
Petershill Partners PLCFull Year Results
Real Estate Investors PLCFull Year Results
Regional REIT LtdFull Year Results
S&U PLCFull Year Results
Softcat PLCHalf Year Results
Synthomer PLCFull Year Results
Team17 Group PLCFull Year Results
United Utilities Group PLCTrading Statement
VH Global Sustainable Energy Opportunities PLCFull Year Results
Xaar PLCFull Year Results
Wednesday 29 March 
abrdn Smaller Companies Income Trust PLCFull Year Results
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Big Technologies PLCFull Year Results
Bowleven PLCHalf Year Results
Central Asia Metals PLCFull Year Results
Ecora Resources PLCFull Year Results
Essentra PLCFull Year Results
Highcroft Investments PLCFull Year Results
Inspired PLCFull Year Results
Medica Group PLCFull Year Results
Michelmersh Brick Holdings PLCFull Year Results
Next PLCFull Year Results
Octopus Renewable Infrastructure Trust PLCFull Year Results
OPG Power Ventures PLCTrading Statement
RM PLCFull Year Results
S4 Capital PLCFull Year Results
Strix Group PLCFull Year Results
Surgical Innovations Group PLCFull Year Results
tinyBuild IncFull Year Results
UP Global Sourcing Holdings PLCHalf Year Results
Thursday 30 March 
AO World PLCTrading Statement
Aquis Exchange PLCFull Year Results
Arbuthnot Banking Group PLCFull Year Results
Ascential PLCFull Year Results
BBGI Global Infrastructure SAFull Year Results
Chesnara PLCFull Year Results
Ebiquity PLCFull Year Results
Gattaca PLCHalf Year Results
Gresham House PLCFull Year Results
IGas Energy PLCFull Year Results
Impellam Group PLCFull Year Results
International Public Partnerships LtdFull Year Results
Ithaca Energy PLCFull Year Results
Microlise Group PLCFull Year Results
Moonpig Group PLCTrading Statement
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Renalytix PLCHalf Year Results
Revolution Beauty Group PLCFull Year Results
Robinson PLCFull Year Results
Secure Trust Bank PLCFull Year Results
Supermarket Income REIT PLCHalf Year Results
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Friday 31 March 
Bank of Cyprus Holdings PLCFull Year Results
Computacenter PLCFull Year Results
Cooks Coffee Co LtdFull Year Results
CT Private Equity Trust PLCFull Year Results
Dignity PLCFull Year Results
ECO Animal Health Group PLCTrading Statement
HealthBeacon PLCFull Year Results
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James Halstead PLCHalf Year Results
Jaywing PLCTrading Statement
JPMorgan American Investment Trust PLCFull Year Results
Numis Corp PLCTrading Statement
Mothercare PLCTrading Statement
Quarto Group IncFull Year Results
UK Oil & Gas PLCFull Year Results
Vanquis Banking Group PLCFull Year Results
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Downing Renewables & Infrastructure Trust PLCFull Year Results
Elixirr International PLCFull Year Results
Fidelity Japan Trust PLCFull Year Results
Gaming Realms PLCFull Year Results
HydrogenOne Capital Growth PLCFull Year Results
N4 Pharma PLCFull Year Results
Renew Holdings PLCTrading Statement
Tracsis PLCHalf Year Results
  
Copyright 2023 Alliance News Ltd. All Rights Reserved. 

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