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Imperial Innovations shares up on portfolio company progress

Thu, 06th Oct 2016 15:15

(ShareCast News) - Imperial Innovations Group updated the market on Thursday, noting that its portfolio company TopiVert Pharma has announced that the first patients have been dosed in its Phase IIa proof-of-concept study to evaluate the safety, tolerability and efficacy of a rectal formulation of TOP1288 in symptomatic ulcerative colitis patients with moderate to severe disease activity.The AIM-traded firm said TOP1288, a potent inhibitor of key kinases involved in inflammation, is being developed by TopiVert as a topical therapy for the form of inflammatory bowel disease which affects the colon.On 17 March, TopiVert reported the successful completion of a Phase I study in healthy volunteers.The clinical data supported the concept that TOP1288 has the potential to produce sustained pharmacological effects in mucosal tissues after local administration, but without the undesirable side effects often seen in UC patients treated with systemically available therapies.Imperial explained that the new Phase II study will evaluate the efficacy, safety and tolerability of TOP1288 administered once daily for four weeks in symptomatic UC patients with moderate to severe disease activity.The study will recruit up to 60 patients at sites across eight European countries and is anticipated to report in the second half of 2017.TopiVert will also commence a follow-on Phase I study with the oral formulation of TOP1288 in early 2017, with that study also expected to report in the second half of 2017."We are delighted by the progress that TopiVert is making, both in its ulcerative colitis trials, but also with its second programme, TOP1630, in dry eye disease, for which a first-in-human proof-of-concept study is planned for early 2017," said Imperial director of healthcare ventures Maina Bhaman.At 1111 BST, shares in Imperial Innovations were up 3% at 435.93p.
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2 Jun 2014 09:13

Imperial Innovation Looks To Raise GBP150.0 Million In Share Placing

LONDON (Alliance News) - Imperial Innovations Group PLC Monday detailed plans to raise up to GBP150.0 million before expenses through a share placing with new and existing investors, as it looks to support its existing portfolio companies, source opportunities to invest in new technologies, and f

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30 May 2014 07:50

Imperial Innovations 44% Owned Veryan Reports Positive Data

LONDON (Alliance News) - Imperial Innovations Group PLC Friday said the third-largest company in its portfolio is set to publish positive new data after a controlled study. In a statement, Imperial Innovations said that Veryan Medical will Friday publish the full two-year data from the Mimi

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22 May 2014 13:08

Imperial Innovations Says JustYoyo Has Completed Investment Round

LONDON (Alliance News) - Imperial Innovations Group PLC Thursday said its portfolio company JustYoyo has completed a GBP2.8 million seed investment round. The investment round for the mobile payments and loyalty company was completing with a second tranche investment, with the first investm

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24 Apr 2014 13:58

Imperial Innovations' Nexeon completes manufacturing facility

Imperial Innovations, the AIM-listed technology group, said that its portfolio company Nexeon has completed the construction and commissioning of its manufacturing facility at its headquarters in Oxfordshire.  Nexeon is Imperial's second-largest portfolio company and develops silicon anode techno

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24 Apr 2014 11:15

Imperial Innovations Says Nexeon Completes Construction Of Headquarters

LONDON (Alliance News) - Imperial Innovations PLC said Thursday its portfolio company Nexeon Ltd has completed the construction and commissioning of its process development and manufacturing facility at its headquarters in Oxfordshire. Nexeon is Innovations' second largest portfolio company

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3 Apr 2014 15:17

DIRECTOR DEALINGS: Imperial Innovations Non-Executive Buys Shares

LONDON (Alliance News) - Imperial Innovations Group PLC Thursday said Non-Executive director David Begg bought 1,470 shares at a price of 403 pence per share. Following this transaction, Begg now holds 21,319 shares, which represents 0.02% stake in the firm. Shares in the software com

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28 Mar 2014 13:14

Imperial Innovations Profit Jumps As Circassia Investment Pays Off

LONDON (Alliance News) - Imperial Innovations Group PLC Friday saw pretax profit rise in the half-year ended January 31, 2014, boosted by the success of its largest investment, Circassia Pharmaceuticals PLC. The technology investment company posted a pretax profit of GBP24.4 million, up fro

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13 Mar 2014 14:22

CORRECTED-UPDATE 2-Allergy drug firm Circassia prices London listing at top of range

(Corrects Reuters Instrument Code to in first paragraph) By Freya Berry LONDON, March 13 (Reuters) - British allergy drug development firm Circassia priced its initial public share offer at the top of its range on Thursday, in the biggest London market debut in years for a biotech com

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13 Mar 2014 08:41

Imperial Innovations' Circassia Prices IPO

LONDON (Alliance News) - Imperial Innovations Group PLC Thursday said its largest portfolio company, Circassia Pharmaceuticals, has successfully priced its IPO on the London Stock Exchange's Main Market. Circassia is expected to raise gross proceeds of about GBP200 million pounds in the pla

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6 Feb 2014 13:55

Imperial Innovations' Circassia to list on LSE main market

Clinical-stage specialty biopharmaceutical company Circassia has announced its intention to float on the London Stock Exchange's Main Market. The company is focused on the development and commercialisation of a range of immunotherapy products for the treatment of allergies, such as those to cats, g

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6 Feb 2014 08:32

UK MORNING BRIEFING: Vodafone Gains, AstraZeneca Falls At Open

LONDON (Alliance News) - Vodafone has delivered results in line with expectations Thursday morning, helping to give UK share a positive start. Vodafone is up 1.4%.

Meanwhile, AstraZeneca has opened down 2.1% after reporting lower revenue and profit

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6 Feb 2014 08:31

UPDATE 1-Circassia seeks $285 mln in bumper UK biotech IPO

* Allergy firm tests European market for larger biotech IPOs * Follows boom in biotech offerings in United States * Funds to help bring cat allergy vaccine to market By Paul Sandle LONDON, Feb 6 (Reuters) - Circassia, a company developing allergy treatments based on a disc

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6 Feb 2014 08:31

UK MORNING BRIEFING:

LONDON (Alliance News) - Vodafone has delivered results in line with expectations Thursday morning, helping to give UK share a positive start. Vodafone is up 1.4%.

Meanwhile, AstraZeneca has opened down 2.1% after reporting lower revenue and profit

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6 Feb 2014 00:01

Allergy drug firm Circassia seeks $285 mln in London IPO

LONDON, Feb 6 (Reuters) - Circassia, a company developing allergy treatments based on a discovery by scientists at Imperial College in London, plans to raise about 175 million pounds ($285 million) of new funds in a stock market debut to bring its cat allergy vaccine to market. Chief execut

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7 Jan 2014 08:22

AIM IN BRIEF: H&T Says Profit As Expected, But Gold Price Has Hurt

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