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* More than 100 being monitored in case they are infected
* Obama says sealing off West Africa would make situationworse
* GlaxoSmithKline says work on developing vaccine movingrapidly
* Canada to ship vials of experimental vaccine to WHO (.)
By Roberta Rampton
WASHINGTON, Oct 19 (Reuters) - With three cases of Eboladiagnosed in the United States and more than 100 people beingmonitored for possible infection, President Barack Obama saidon Saturday that Americans "can't give in to hysteria or fear"about the spread of the virus.
While Obama administration and world health officialsremained focused on tackling Ebola at its source in three WestAfrican countries, Texas state authorities said 14 people hadbeen cleared from an Ebola watch list. Three weeks of monitoringfor fever and other symptoms was expected to end for others inthe next two days if they remained asymptomatic.
Those include Louise Troh in Dallas, fiancée of the nowdeceased Liberian Thomas Eric Duncan, who became the firstU.S.-diagnosed Ebola case in late September while visiting her.Troh, her 13-year-old son and two Duncan relatives have been inmandatory quarantine in Dallas that ends on Sunday.
The Texas Department of State Health Services said in astatement that 145 people with "contacts and possible contacts"with the virus were being monitored.
In his weekly radio address, Obama made plain he does notplan to accede to demands from some U.S. lawmakers for a ban ontravelers from Liberia, Sierra Leone and Guinea, the worst-hitcountries, where more than 4,500 people have died since March inthe worst Ebola outbreak on record.
"We can't just cut ourselves off from West Africa," Obamasaid. "Trying to seal off an entire region of the world, if thatwere even possible, could actually make the situation worse."
Obama, who has been criticized over his administration'shandling of Ebola, held a flurry of meetings this week and onFriday appointed Ron Klain, an experienced Washington lawyer, to oversee efforts to contain the disease.
Republicans questioned why he did not pick a medical expert.
"I hope he (Klain) is successful in this. I think it's astep in the right direction, but I just question picking someonewithout any background in public health," Republican Rep. andHouse Foreign Affairs Committee chairman Ed Royce told CNN.
The World Health Organization has also been faulted forfailing to do enough to halt the spread of the virus.
The WHO said it would publish a full review of its handlingof the crisis once the outbreak was under control.
There is no cure or approved vaccine yet for Ebola butpharmaceutical companies have been working on experimentaldrugs. The virus is transmitted through an infected person'sbodily fluids and is not airborne.
Canada said on Saturday it would ship 800 vials of itsexperimental Ebola vaccine, undergoing clinical trials, to theWHO in Geneva, starting on Monday. Iowa-based NewLink GeneticsCorp holds the commercial license for the Canadianvaccine.
Britain's biggest drugmaker, GlaxoSmithKline, said work to develop a vaccine was moving at an "unprecedented rate"and the next phase, if successful, involving vaccinatingfrontline healthcare workers, would begin in early 2015.
FEAR
Obama sought to put the extent of the disease in the UnitedStates in perspective. "What we're seeing now is not an'outbreak' or an 'epidemic' of Ebola in America," he said. "Thisis a serious disease, but we can't give in to hysteria or fear."
A series of Ebola scares has hit the country since Duncan,who died on Oct. 8, was diagnosed. Americans'faith in the medical system and in its disease prevention ability was jolted by early missteps in his case.
In a public letter on Saturday night, Texas Health ResourcesChief Executive Barclay Berdan acknowledged that the TexasHealth Presbyterian Hospital where Duncan first went "mademistakes in handling this very difficult challenge," includinginitially not correctly diagnosing his symptoms.
Berdan said aggressive actions and changes since thenensured that the hospital was "a safe place" for patients andstaff, and that outside experts would be consulted to determinehow two nurses caring for Duncan became infected with Ebola.
Amber Vinson is at Atlanta's Emory University Hospital,while Nina Pham is being treated at the National Institutes ofHealth outside Washington.
People who had contact with them or Duncan are beingmonitored, while some 800 passengers who flew with Vinson on atrip she made to Ohio before being diagnosed, as well as those on subsequent flights on the same planes, have been contacted by Frontier Airlines, it said on Saturday.
Also being monitored are a lab worker at the hospital who isnot ill but is in isolation at sea in her cabin on the CarnivalMagic cruise ship owned by Carnival Corp. The worker hadno contact with Duncan but may have come in contact with testsamples. The ship was on its way back to Galveston, Texas.
The Ohio Department of Health strengthened its recommendedEbola quarantine protocols to limit travel by those required tohave their health condition monitored locally or report it toofficials. Ohio said its vigilance was meant to exceed CDCrecommendations.
Obama has stressed that containing Ebola should include helpfor the worst-hit countries and Washington plans to deploy up to4,000 military personnel to the region by late October. He ispreparing to ask Congress for additional Ebola funding.
British Prime Minister David Cameron said on SaturdayEuropean Union leaders should raise the amount pledged to fightEbola to 1 billion euros ($1.3 billion) and mobilize at least2,000 workers to head to West Africa. A spokeswoman at Cameron'soffice said the EU commission and 28 member states had pledged atotal of 500 million euros so far.
(Additional reporting by Mohammad Zargham and Eric Beech inWashington, Frank McGurty in New York, Anna Driver in Dallas,Tom Miles in Geneva and Costas Pitas in London; Writing byFrances Kerry and Megan Davies; Editing by Grant McCool, ChrisMichaud and Clarence Fernandez)
