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Evgen Pharma receives approval for breast cancer study

Wed, 17th Aug 2016 10:49

(ShareCast News) - Clinical stage drug development company Evgen Pharma announced on Wednesday that it has received a Clinical Trial Approval from the UK's regulatory agency for the commencement of its Phase II clinical trial of SFX-01 in breast cancer.The AIM-traded firm said patient recruitment will begin in the UK at Manchester's Christie NHS Foundation Trust following Research Ethics approval, which is expected during the coming weeks.Further regulatory and Research Ethics approvals are also expected shortly at various sites across Europe for the multi-centre study, the board reported.It said the STEM (SFX-01 in the Treatment and Evaluation of Metastatic Breast Cancer) trial will investigate SFX-01 in combination with different hormone-based therapies in 60 metastatic breast cancer patients whose cancer cells are estrogen-receptor positive (ER+).The primary objectives of the STEM trial are to evaluate safety and efficacy via tumour imaging in patients starting to become resistant to mainstream hormone therapy.Patients will be enrolled into one of three study arms - SFX-01 in combination with either aromatase inhibitors, tamoxifen or fulvestrant - based on their current therapy.It will be led by chief investigator Dr Sacha Howell at Manchester's Christie NHS Foundation Trust, Europe's largest single-site cancer centre, and include several other sites across Europe.The company says first patient is expected to be recruited in October 2016."Many therapies used in cancer ultimately fail as patients develop resistance - one hypothesis is that this resistance is driven by cancer stem cells which, unlike a mature cancer cell, do not respond to current standards of care," said Evgen CEO Dr Stephen Franklin."Our excitement with SFX-01 is that it targets the cancer stem cell population and therefore has the potential to improve the efficacy and longevity of a range of drugs used in cancer therapy - both approved drugs and those in clinical development."
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13 Oct 2022 17:55

CORRECT: Coral Products buys Ecodeck; Evgen Pharma recruits

(Correcting Harmony Energy Income Trust's use of funds.)

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12 Oct 2022 21:46

TRADING UPDATES: Coral Products buys Ecodeck; Evgen Pharma recruits

(Alliance News) - The following is a round-up of updates by London-listed companies, issued on Wednesday and not separately reported by Alliance News:

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12 Oct 2022 12:23

Evgen starts recruiting volunteers for trial of lead asset

(Sharecast News) - Clinical-stage drug development company Evgen Pharma announced the start of recruitment for the pharmacokinetic and pharmacodynamic trial in healthy volunteers, and the decision to commence an investigator-sponsored clinical study for the glioblastoma programme on Wednesday.

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10 Oct 2022 12:10

LONDON MARKET MIDDAY: FTSE 100 trims opening loss amid Fed hike worry

(Alliance News) - European equities traded off session lows heading into Monday afternoon, finding some poise after a poor open, as markets deal with the fallout from last week's US jobs report.

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10 Oct 2022 11:00

AIM WINNERS & LOSERS: Europa Oil, i3 Energy slide as well disappoints

(Alliance News) - The following stocks are the leading risers and fallers on AIM in London on Monday.

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10 Oct 2022 09:58

Evgen Pharma shares jump 65% as licences SFX-01 composition for autism

(Alliance News) - Evgen Pharma PLC on Monday said it has signed a licencing deal for up to USD160.5 million with Stalicla SA for the global rights to its lead asset SFX-01 in neurodevelopmental disorders and schizophrenia.

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14 Jul 2022 16:39

UK shareholder meetings calendar - next 7 days

Friday 15 July 
Aveva Group PLCAGM
DCC PLCAGM
DP Poland PLCAGM
Griffin Mining LtdAGM
MC Mining PLCGM re subscription
Monday 18 July 
Audioboom Group PLCAGM
JPMorgan European Discovery Trust PLCAGM
Tuesday 19 July 
Biotech Growth Trust PLCAGM
Clean Power Hydrogen PLCAGM
e-Therapeutics PLCAGM
Norcros PLCAGM
Ten Lifestyle Group PLCGE re commitment to sustainability, B Corp certification
Wednesday 20 July 
ADM Energy PLC AGM
Alkemy Capital Investments PLCAGM
DeepVerge PLCAGM
easyJet PLCGM re purchase of 56 Airbus A320neo family aircraft & conversion of 18 A320neo family aircraft
Fidelity China Special Situations PLCAGM
HarbourVest Global Private Equity LtdAGM
HICL Infrastructure PLCAGM
Novacyt SAAGM r
Plaza Centers NVAGM
Premier Foods PLCAGM
Royal Mail PLCAGM
Triad Group PLCAGM
Wynnstay Properties PLCAGM & GM re share buyback
Thursday 21 July  
Big Yellow Group PLCAGM
Evgen Pharma PLCAGM
Experian PLCAGM
Halma PLCAGM
Intermediate Capital Group PLCAGM
Johnson Matthey PLCAGM
Octopus AIM VCT PLCAGM
Pennon Group PLCAGM
Pires Investments PLCGM re offer from Tern PLC
QinetiQ Group PLCAGM
SSE PLCAGM
Tern PLCGM re offer for Pires Investments PLC
Vp PLCAGM
Workspace Group PLCAGM
Zephyr Energy PLCAGM
  
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13 Jun 2022 19:22

IN BRIEF: Evgen to work with University of Michigan on asset SFX-01

Evgen Pharma PLC- Cheshire, England-based drug development company - Announces collaboration with University of Michigan, to investigate the potential anti-tumour effects of the company's lead asset SFX-01 in colorectal cancer.

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8 Jun 2022 14:26

Evgen Pharma starts trial to test breast cancer tablet; loss narrows

(Alliance News) - Evgen Pharma PLC on Wednesday said it would begin a trial to test a new medicinal product later this year and said its results for the most recent financial year are in line with expectations.

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25 May 2022 22:02

TRADING UPDATES: Tekcapital fundraise; Kromek wins US government order

(Alliance News) - The following is a round-up of updates by London-listed companies, issued on Wednesday and not separately reported by Alliance News:

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18 Jan 2022 11:48

Evgen agrees fresh licensing deal with Spanish institutions

(Sharecast News) - Clinical-stage drug development company Evgen Pharma announced a memorandum of understanding with the University of Seville, Consejo Superior de Investigaciones Científicas (CSIC) and Fundación Pública Andaluza Progreso y Salud on behalf of the Institute of Biomedicine of Seville on Tuesday, for second-generation sulforaphane analogues.

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18 Jan 2022 11:32

Evgen signs agreement for Spanish institutions' sulfoaphane analogues

Evgen signs agreement for Spanish institutions' sulfoaphane analogues

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7 Dec 2021 21:49

EARNINGS UPDATES: Carr's beats expectations; Premier assets hit record

EARNINGS UPDATES: Carr's beats expectations; Premier assets hit record

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30 Nov 2021 16:26

UK earnings, trading statements calendar - next 7 days

UK earnings, trading statements calendar - next 7 days

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10 Nov 2021 18:22

TRADING UPDATES: Permanent TSB sells loan portfolio; Dekel output up

TRADING UPDATES: Permanent TSB sells loan portfolio; Dekel output up

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