Shire was performing well after Credit Suisse reiterated its outperform recommendation and 2,350p target on the stock. Barclays remains in the red, despite a generally favourable reception to its third quarter figures, as banks dragged the index lower. Nomura has reiterated its buy call on banking giant Barclays, while Credit Suisse has stuck with its "outperform" rating and 200p price target. Miners are a major drag on the index, with Vedanta leading the way lower followed closely by Kazakhmys after Japan's intervention into the currency markets and Chinese demand worries spurred a fall in commodity prices. FTSE 100 - RisersGlaxoSmithKline (GSK) 1,403.50p +1.41%Morrison (Wm) Supermarkets (MRW) 305.10p +1.26%Shire Plc (SHP) 1,985.00p +1.17%United Utilities Group (UU.) 614.50p +1.15%BT Group (BT.A) 189.40p +0.80%Severn Trent (SVT) 1,543.00p +0.59%Vodafone Group (VOD) 175.30p +0.57%National Grid (NG.) 625.50p +0.48%SSE (SSE) 1,351.00p +0.45%Tesco (TSCO) 406.65p +0.30%FTSE 100 - FallersVedanta Resources (VED) 1,308.00p -6.84%Kazakhmys (KAZ) 954.00p -6.19%Xstrata (XTA) 1,065.00p -5.96%ICAP (IAP) 409.10p -5.43%Man Group (EMG) 145.30p -5.28%Lloyds Banking Group (LLOY) 33.38p -5.04%Royal Bank of Scotland Group (RBS) 25.01p -4.87%Aviva (AV.) 345.90p -4.71%BHP Billiton (BLT) 2,005.00p -4.61%Eurasian Natural Resources Corp. (ENRC) 668.00p -4.57%NR