(Adds background, details on Austria)
FRANKFURT, Jan 22 (Reuters) - Europe's COVID-19 vaccination
drive was dealt another blow on Friday when AstraZeneca
said initial deliveries to the region will fall short of the
targeted volumes because of a production glitch.
"Initial volumes will be lower than originally anticipated
due to reduced yields at a manufacturing site within our
European supply chain," a company spokesman said in a written
statement, declining to provide details.
The slippage hits a European immunisation campaign that has
already been hampered by a temporary shortfall in the supply
chain of vaccine developers Pfizer and BioNTech
, who are retooling a site in Belgium to boost output.
The EU Commission said Astra had informed the EU's
vaccination steering board of a change of its delivery schedule
and that the Commission was working to find out more.
While BioNTech's product, as well as a vaccine made by U.S.
biotech firm Moderna, have already been launched after
winning regulatory clearance, an EU decision on regulatory
approval of Astra's compound is expected by the end of January.
"We will be supplying tens of millions of doses in February
and March to the European Union, as we continue to ramp up
production volumes," the British drugmaker, who is partnering
with Oxford University, said. The spokesman would not provide
the initial volume target.
The EU has struck a deal to purchase at least 300 million
doses from Astra, with an option for an additional 100 million,
part of the company's global commitments to supply more than 3
billion doses.
Austrian Health Minister Rudolf Anschober warned AstraZeneca
that any delay would be "absolutely unacceptable", though he
stopped short of confirming reports in Austrian media that the
company had told the country it could only supply 600,000
vaccine doses in the first quarter rather than the 2 million
originally planned.
"Agreed delivery amounts must be stuck to," Anschober said
in a statement after reports by media, including newspaper
Kurier and national news agency APA.
Austrian Chancellor Sebastian Kurz said on Monday he and his
counterparts from Denmark and Greece would pressure the European
Medicines Agency to rapidly approve AstraZeneca's vaccine. The
Baltic states and the Czech Republic have joined that
effort.
(Reporting by Ludwig Burger in Frankfurt, Francois Murphy in
Vienna; Additional reporting by Francesco Guarascio in Brussels.
Editing by Edward Taylor and Jane Merriman)