Chris Heminway, Exec-Chair at Time To ACT, explains why now is the right time for the Group to IPO. Watch the video here.
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Sparkle,
Have you considered that the double jab may be a possibility why you have been floored?
Echo those good wishes, Mat, to sparklehorses and to all who fall foul of this evil disease - the quicker SNG001 gets authorised as an effective remedy and out to all sufferers, the better.
Still amazed that whereas the vacs were, quite understandably, rushed out as an emergency, foregoing the usual prolonged efficacy tests, this treatment still has to go through the grind of validation to be proven as effective.
Ah well, soon it will be confirmed, hopefully and rapidly deployed - sasa.
Hope you have a speedy recovery sparkle.
Sparklehorses. I have left side hemiplegia which is quite similar to long covid. I take Multibionta vitamins. Helps me a lot.
Regards.
Totally agree - doubled jabbed and consider myself to be a very fit fifty something ( ultra marathon runner) but Iit has floored me for the past few days!
Prion, There is a certain % of the population after double vaccination that still gets sick and ends up in hospital. Despite lots of statistics being bandied about from both sides of the fence no one knows the exact % as yet or if the benefits of the double vaccination are long lasting or wane quickly. As the two front runners vaccination - the UK is about to re-vaccinate 30 odd million people, the Israeli's are revaccinating again - I think the authorities know some these answers!
In any case there is and will be for the foreseeable future a very real need for SNG001 if it can prove itself in this current P3. I have seen nothing in the scientific literature around covid and INF that would suggest SNG001 should not be highly effective as a treatment. Hopefully the P3 final dosing occurs in the next month and we can get a readout in October.
Thanks again Mat
I been asking that question from day one and always felt it was a weakness in the vaccination policy especially for the most vulnerable people it was meant to protect,but they seemed to ignored the science and our treatment regardless .ATB
"If an individual as a blunted innate interferon response and is double vaccinated would they acquire adequate protection through vaccination or not ?"
Prion, I am not sure anyone really knows the exact answer to that yet. There is a study ongoing at present for young healthy adult men without medical history who develop severe covid due to mutations in the TLR7 gene. This is a gene that initiates the initial interferon (antiviral) response. The study is looking at preventative vaccination for this subgroup but data not available yet.
https://www.eurekalert.org/news-releases/924281
Thanks Mat
Endless good Scientific evidence of the role of interferon on severe disease .If an individual as a blunted innate interferon response and is double vaccinated would they acquire adequate protection through vaccination or not ?
Brilliant find Matml. Thankyou.
Would the strategy therefore be to have regular interferon tests to check your levels and take a 'top up' if required or it appears RM is saying only take SNG if you are having trouble breathing? Is he pushing against an open door?
Either way it sounds like the world could do with interferon.
Paper- Induction of interferon response by high viral loads at early stage infection may protect against severe outcomes in COVID-19 patients
“ Finally, we found a strong inverse correlation between upregulation of interferon responses and disease severity. Overall our study suggests that a high viral load in the upper respiratory tract may not be a critical factor for severe symptoms; rather, dampened antiviral responses may be a critical factor for a severe outcome from the infection.”
“We found a strong correlation between interferon responses and viral load, which inversely correlates with clinical severity. We postulate an interplay of these three factors where a strong up-regulation of antiviral responses mediated by high viral loads at the initial phase have led to protective immune responses.”
https://www.nature.com/articles/s41598-021-95197-y