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Gkb- it does, but what I was trying to say was that the virus gains entry via the lungs to potentially spread to other organs. SNG’s direct application to the lungs could prevent this progression. You wouldn’t then need to inject anything and the unpleasantness that brings on.
FOMO 2 weeks away from trial results, can wait this will be massive
I don't really see the point in Faron's traumakine.
It'd be like saying to Asthma patents, you can't have your inhaler, we're going to march you in and out of hospitals for injections instead.
Talking about their patents they say "Interferon-beta, especially if freeze-dried, is known to form aggregates or stick to container surfaces, requiring careful control of dosing and in-use stability during administration."
Well whoopy do....you've got something that doesn't stick to a container and needs someone carefully administering in hospital.....
SNG's inhaled version looks a far more distributable and marketable proposition.
Be nice for the government to pick up on SNG001 in one of there news briefings though wouldn’t it ? Or does our face not fit enough ?? Gla and have a swing yer pants kinda weekend ;-))
The dosing levels of ifn beta 1a is going to be the key , imo
Will have to wait and see
Simple question... Would Synairgen continue with a trial if it was obvious it wasn't working? Surely it would be morally wrong to do so let alone financially wrong, especially since we've seen other companies pull their trials.
This is not a hidden outcome...if its working the everyone involved will see the effects of a much speedier recovery.
So,let's just assume all is and has gone well in the hospital trial can we then assume the home trial is simply a matter of course...
Thing with Faron is that it would appear to be targeted more towards the systemic problem once the virus has taken hold. Injecting Interferon in this way will increase side effects which can be serious in already sick patients. The beauty of SNG001 is as we all know is that it is delivered directly to the lungs thus avoiding direct entry to the avascular network. If You block the virus penetrating the lining of the lungs, then you can stop avascular entry and someone progressing onto that bad second or third week hopefully.
https://www.thelancet.com/pdfs/journals/lancet/PIIS0140-6736(20)31042-4.pdf
and this leans towards the triple threat being better than the double threat. RECOVERY dropped the double threat so you would be fair to assume the triple threat only works because of IFN-Beta.
Interferon beta 1a. Is Faron in the IV format
and the RECOVERY trial recently ruled out Lopinavir/ritonavir combined.
So if the triple threat of Lopinavir/ritonavir combined with interferon-beta proves successful that would be more clout behind IFN beta.
Well it would be quite handy if the WHO come out and say interferon beta helps a lot....as SNG have the patent for the inhaled delivery form for most of the world, which you can package up and ship out to everyone, and don't need to come to hospitals for injections of it.
Exactly might shine the spotlight on IFN-beta then we can follow up showing the performance of it inhaled by itself.
Remdesivir
Lopinavir/ritonavir combined
Lopinavir/ritonavir combined with interferon-beta
Hydroxychloroquine or chloroquine (discontinued due to no benefit, June 2020)[12]
Interferon beta 1a is on the list.
Could this be us? https://www.reuters.com/article/us-health-coronavirus-who/who-sees-first-results-from-covid-drug-trials-within-two-weeks-idUSKBN244219