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Good morning citizen79. Interesting post. I note the following:- Note it states 'treating lupus like disease'. It dont state we are treating Lupus.
This research project explored the use of small molecule inhibitors of Tyk2 and Jak1 for treating lupus like disease pathology in mouse models of lupus. In our findings we report that 6-week treatment of lupus-proneNZBxNZWF1 mice with small molecule inhibitor of Tyk2Jak1 significantly lowers the pathological auto-antibody production. Similar treatment in MRLlpr model of lupus did not have any effect. The treatment ofNZBxNZWF1 mice also leads to a drop in the number of germinal centers in the spleen as well as a decrease in spleen weights. Since lupus is a chronic disease, we think that a prolonged treatment 6 weeks will show more profound effects on other lupus related disease pathologies like kidney damage. Over all, the treatment has shown potential for significantly improving the disease pathology in NZBxNZWF1 mouse model of lupus.
Regards
SOG as I mentioned before I'm possibly being a bit more cryptic in what I write on here from now on. But like I say I read some interesting comments re lupus very recently and how symptoms might be 'similar' to possible adverse reactions from something else.
The study went that well the sent the main chap back to India to slow it down- oh well the DOD know a hell of lot more than they are letting on me thinks.
The PI on this project, Dr. Abhishek Trigunaite, had to travel to his home country (India) for immigration related issues (VISA stamping).
Because of the unanticipated length of the processing time, he was required to stay in India for nearly3 months and only able to return close to the termination date of the project.
I would hazard a guess nothing to do with Lupus at all, but sounds very much better and less catastrophic than effects against a weapons grade corona virus .
According to the Lupus Foundation of America, approximately 1.5 million people in the U.S. have lupus. People of African, Asian, and Native American descent are more likely to develop lupus than are Caucasians. Although it can occur in both men and women, 90% of people diagnosed with the disease are women.
I certainly would not see a threat to the military with these figures, Approx 1 in 300 people have Lupus and of these 90% are women. Clearly the US military have identified this as a problem that needs looking at.
All very very coincidental with Gain of function being financed by NIH since 2017.
Equally Citizen
Thank you Rebster
Many thanks all for the link and RNS date. I wonder why it was not so very long ago the US military was so keen to look at one of our molecules specifically regarding Lupus.
I note reading today that Biden is looking at a way to put through a policy for it to be mandatory for all 1.3m military personnel to be vaccinated re covid.
Link here Ahfam, the Defense department changed their site setup a few months back:
https://apps.dtic.mil/sti/citations/AD1087498
https://apps.dtic.mil/sti/pdfs/AD1087498.pdf
ATB
Ahfam
Here you go
https://apps.dtic.mil/sti/citations/AD1087498
the last bracket and full stop got caught in the hyperlink..
Doesn't work for me for some reason
Steady go to the 24 July 2020 RNS and the link is there-
These studies were supported by a research grant from the US Department of Defense (DoD) and the report was recently published on the website of the Defense Technical Information Center (https://apps.dtic.mil/sti/citations/AD1087498).
Good morning SOG. Rather blustery here today.
Could I ask when where can I find the relevant release re US troops and lupus program?
Been reading some interesting comments elsewhere re lupus concerns.
Best regards Steadydanny
Good morning Steadydanny. A cheeky grin yes , I would think Tim has even more of a grin now with a circa 250 million market cap. With so much doom and gloom at the moment a sniff of positive news in any shape or form and SP will go ballistic.
I have said before the silence is deafening.
Regards
As has been said you can't help but smile when you see it
"for the right price'
Eyebrows up and a bit of a cheeky grin.
Monoclonal antibodies fail doubled our mcap.
Delta beta and lamda no becoming less virulent. But more so. Doubled again.
Wait for the market to catch up. It will. And its time boxed. Gla.
"For the right price"
came out of my mouth in Russian.
'Two separate licensing packages' per molecule or If a BIG Pharma wants it all. Tim is willing to sell.
"We've applied to ONE so far, but there's others to come of the government grants available...... without dipping too much into our own pockets."
Ehm enter Melinda/HNWIs £5m to over £30m - ("To qualify, firms will have to be UK-based and seeking 'at least' £30m to fund further development.")
One deal, would put Sareum properly on the map. Start a war, I mean a bidding war. A little longer. This month let's hope it begins, the rerate that is.
No interviews since, now why cold that be ??
Lol batton. If eyes could talk
Yeah, and at 2.39 the eyebrows reveal everything :)
Let’s recap last year’s trading update Tim’s interview
Note the statement around 2.20 in.
https://m.youtube.com/watch?v=h6zdOkooHzY