Proposed Directors of Tirupati Graphite explain why they have requisitioned an GM. Watch the video here.
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Here is a link to Espacenet the Worldwide Patent Library with Paraytec (Braveheart) list of patents invented by the genius Professor David Goodall CHIEF SCIENTIFIC OFFICER OF PARAYTEC
https://worldwide.espacenet.com/searchResults?ST=singleline&locale=en_EP&submitted=true&DB=&query=Paraytec
Look at item number 5 Optical assembly and method for detection of light transmission link below
https://worldwide.espacenet.com/publicationDetails/biblio?II=4&ND=3&adjacent=true&locale=en_EP&FT=D&date=20051020&CC=US&NR=2005231718A1&KC=A1
An optical assembly comprising a light source, at least one sample vessel and a detector, the at least one vessel being positioned in a light path or paths created between the source and the detector in manner to enable transmission of light through the vessel wherein the light source is adapted to provide a beam of substantially collimated light, the detector comprises a plurality of detector locations and the vessel comprises a wall and core of relative shape and dimensions adapted to contain a sample for detection and to define at least two spatially separated transmitted light paths, a first wall path which enters and exits the vessel walls only, spatially separated from a second core path which enters and exits the vessel walls and additionally the vessel core, wherein the spatially separated wall and core paths are coupled to individual detector locations on the detector, a module or clip-on device therefor, method for detection and uses thereof.
I suspect that this is some of the technology integrated into our Paraytec 2-minute test. There is a lot of information on the other items 1 to 4 all highly advanced science of which we are proud to be invested at the FRONTIER!
It is great to know that Paraytec’s patents are in place so our IP is protected meaning potential global sales and earnings.
Thoughts anyone ?
Look at item number 4 could this be a diagram of our 2 minute test device ?
Link below
https://worldwide.espacenet.com/publicationDetails/biblio?II=3&ND=3&adjacent=true&locale=en_EP&FT=D&date=20100909&CC=US&NR=2010225898A1&KC=A1
An optical apparatus and method comprising a light source, an array detector for area imaging and an optical cell assembly. The optical cell assembly comprises a chamber which is arranged to receive a sample of a material including an analyte, a fluid inlet and a fluid outlet coupled to the chamber. A fluid dissolution medium stream passes through the chamber such that the sample can dissolve into the dissolution medium. The chamber is in at least one light path created between the light source and the array detector. The array detector comprises a two dimensional array of detector locations arranged to provide an output signal indicative of the light absorbance of the analyte within the chamber such that the output of the array detector is indicative of the concentration profile of the analyte near the surface of the sample.
Good find: starknight
StarkNight, on one of the diagrams, says ce ?
Stampee
Thanks mate ....... Hey I missed that WOW then an RNS with good news might be coming sooner than we all think !
FULL DESCRIPTION OF DEVICE
https://worldwide.espacenet.com/publicationDetails/description?CC=US&NR=2005231718A1&KC=A1&FT=D&ND=4&date=20051020&DB=&locale=en_EP
[0001] The present invention relates to an optical assembly comprising a sample vessel positioned in a direct light path between a light source and a light detector, in manner to enable transmission of light through the vessel; a method for detection of light transmission through sample contained within the vessel; an apparatus comprising the assembly; more particularly an apparatus for sample analysis for example for high throughput screening (HTS) or profiling or assays, such as enzyme assays; and uses thereof in the pharmaceutical, biomedical and bioscience, agrochemical, veterinary, materials and like fields, for detection, analysis, characterisation and quantification or the like of samples contained in a vessel, and optionally further collecting separated components thereof; in particular in combinatorial chemistry; in metabolomics, proteomics or genomics, assay and high throughput analysis applications, typically high sensitivity analyses, separation and/or quantification studies and for sample separation for example chromatography or electrophoresis, in particular column chromatography, capillary electrophoresis with real time or post separation analysis.
[0002] UV absorbance, fluorescence and mass spectrometry are key technologies used in separation science for analysing species in samples. A particularly useful methodology is to look at a sample population separated by capillary electrophoresis with fluorophore labelling and fluorescence imaging, for quantification, and MS for characterising molecules of interest.
[0003] U.S. Pat. No. 5,582,705 discloses an apparatus and system for laser induced fluorescence (LIF) detection in a multiplexed capillary electrophoresis system. A coherent beam incident on the capillary array and emitted fluorescent light are typically perpendicular to each other in order to reduce background noise due to light scattering. A transparent portion in each capillary wall defines a transparent path extending through the array, perpendicular to the capillary. A 2D image array detector such as a charge-coupled device (CCD), preferably a charge-injection device (CID), is positioned to detect emission, and an imaging lens interposed between the capillary array and the image array detector, to optically couple the pixels to the capillary. The imaging lens may be any lens capable of transforming an image onto the pixels of the image array detector, such as a camera lens or a condenser lens. Coupling is shown in FIG. 4, of U.S. Pat. No. 5,582,705 in which every second pixel is coupled to a sidewall of the capillary and every pixel in between is coupled to an interior portion.
[0004] Fluorescence detection is limited in its application since only a limited number of molecules are naturally fluorescent and many have to be derivatised in reproducible and quantitative manner. Absorbance detection therefore has the advantage of enabling detection of a wider range of molecules. For example in enzyme assays, conducted in microtitre wells, techniques can be extended to absorbance detection of chromophoric, UV and vis absorbing substrates consumed or produced in an assay, extending the range of assay to natural as well as synthetic substrates.
[0005] However a limitation of absorbance detection lies in the operable wavelength of detection. Absorbance detection is conducted on substrates in solution. However many common solvents absorb significant amounts of light at wavelengths below 200 nm, and the resulting solvent absorption signal distorts and masks signals resulting from the substrate to be detected. Accordingly absorbance detection is in practice limited to detection at wavelengths in excess of 190 nm, in the range UV-vis to near infra-red (NIR).
[0006] Moreover a fundamental limitation of single point absorbance detection is the impossibility of creating an image of the source at the detection point on capillary that is brighter than the light source. In "A charge coupled device array detector for single-wavelength and multi-wavelength ultraviolet absorbance in capillary electrophoresis", Bergstrom and Goodall, Pokric and Allinson, Anal. Chem. 1999, 71, 4376-4384 discloses optical detection in capillary electrophoresis by means of absorbance detection, illuminating a length of the capillary using a fibre optic bundle and using a charge coupled device (CCD) camera to image the full length of the illuminated zone. In this publication light from a fibre optic bundle is focused by a sapphire rod through the capillary core and detected on the opposite side of the capillary, by this means, increasing the target light area enabling more of the lamp output to be used and increasing the total light flux. In this case light emanates from the capillary core, so all light detected is useful and the divergent beam obtained is imaged on to the CCD.
[0007] Such a system becomes more complex once a parallel capillary array is introduced in place of the single capillary. Optics to focus light on the core of each capillary would be extremely complex and therefore irradiating both the core and walls of each capillary becomes a practical consequence.
[0008] WO 01/18528 (Yeung et al) discloses a method for analysing multiple samples simultaneously by absorption detection of samples in a planar array of multiple containers, whereby stray light from adjacent containers is eliminated by distancing the detection means from the array, preferably at a distance greater than 10 times the diameter of a container, suitable 10-100 times the diameter for example at a distance of 1-30 cm. Containers are preferably cylindrical capillary tubes as shown in the art. The array comprises a control container if the light source is unstable. It is stated that the cross section of the container and thickness of the capillary wall are not critical. A flat field lens preferably images the containers on to the detection means.
[0009] We have now found that further improvements in absorbance detection assemblies enables increasing the total light flux through a capillary or other sample vessel, by virtue of simplification of optical components, without unduly large separation of capillary and detector which is undesirable and reduces light collection efficiency compromising path length, and therefore light intensity. The improved assembly is of particular advantage in detection in multiplexed capillary arrays and enables imaging a large area of a capillary array without the need for imaging optics. This is a significant advantage, especially when working in UV for which it is very difficult and expensive to produce suitable optics. The assembly has benefits however in both single capillary and array detection, in particular enabling a simple and improved exposure referencing and acceptably low intercapillary cross talk without the need for optics. In addition a benefit of the assembly of the invention is that it is suitable for operation at short pathlengths, by virtue of the increased total light flux through the core of the capillary or other sample vessel, and this reduction in pathlength may lead to opportunities to conduct absorbance detection at lower wavelengths, less than 190 nm, without encountering impracticably high levels of solvent absorption.
[0010] Accordingly there is provided in the broadest aspect of the invention an optical assembly comprising a light source, at least one sample vessel and a detector, the at least one vessel being positioned in a light path or paths created between the source and the detector in manner to enable transmission of light through the vessel wherein the light source is adapted to provide a beam of substantially collimated light, the detector comprises a plurality of detector locations and the vessel comprises a wall and core of relative shape and dimensions adapted to contain a sample for detection and to define at least two spatially separated transmitted light paths, a first wall path which enters and exits the vessel walls only, spatially separated from a second core path which enters and exits the vessel walls and additionally the vessel core, wherein the spatially separated wall and core paths are coupled to individual detector locations on the detector.
[0011] Preferably the detector is an array detector. Preferably the detector is adapted to detect and provide information on respective wall and core path light transmission. Preferably the assembly is coupled to means for displaying information on respective wall and core path light transmission or for displaying referenced information on core path light transmission, referenced against wall path light transmission.
[0012] Preferably the assembly defines a central core path and two peripheral wall paths either side thereof or an annular wall path thereabout. Paths may overlap on emerging from the vessel and at greater separations from the vessel. Preferably the wall and core paths are coupled to detector locations at a vessel outer wall to detector separation or distance d at which the paths are spatially separated, preferably giving more than 90% separation of core and wall beam fluxes. The assembly may position the vessel in two or more separate light paths to generate two or more sets of spatially separated transmitted light paths coupled to two or more detectors or detector zones.
[0013] Preferably the assembly is characterised by internal vessel dimension or path length in the range of 3 [mu]m to 20 mm, external vessel dimension in the range 4 [mu]m to 30 mm, refractive index of vessel wall in the range 1.3-<1.6, vessel outer wall to detector separation d in the range 10 [mu]m to >300 mm and is for use in detecting a sample comprising analyte in solvent having refractive index in the range 1.3 to in excess of 1.5. Reference herein to a sample is to vessel contents which may comprise a single or multiple components. Multiple components may be present as a homogeneous or heterogeneous mixture, and may undergo migration with time ie may be a plurality of liquid phase components optionally including a dissolved phase component; or may include one or a plurality of analytes which it is desired to detect in one or a plurality of solvents or like bulk phase sample component, for example in the course of a chemical reaction generating or consuming a species as analyte.
[0014] In a particular advantage, the apparatus of the invention enables exposure referencing of a light beam traversing a core path of the at least one sample vessel, by a light beam traversing a wall path of the same sample vessel. The beams are spatially close, preferably adjacent, on the array detector, facilitating direct referencing as the ratio of the core beam to the wall beam. In a further advantage the two light beams are of neighbouring origin whereby core and wall beams have a high probability of emanating from the same region in the light source eliminating the effects of light source fluctuations due to e.g. instability or spatial inhomogeneity. The assembly of the invention is therefore able to operate at the shot noise limit.
[0015] Preferably the light source comprises any active or passive light source, for example light may be generated at the source or it may be transmitted to the source and emanate therefrom, for example it may be transmitted by an optical fibre to the light source. Preferably the light source comprises at least one wavelength of light that is absorbed by one or more absorbing species, the absorbance of which is to be detected. For example the light source output may be coupled from a fibre optic if desired for illumination from a remote light generator or may be coupled from a point to line optical fibre for zone illumination. Coupling the output into a single optical fibre reduces noise contributions caused by fluctuations in the spatial distribution of the lamp discharge.
To much to post on here the full article link below reposted
FULL DESCRIPTION OF DEVICE
https://worldwide.espacenet.com/publicationDetails/description?CC=US&NR=2005231718A1&KC=A1&FT=D&ND=4&date=20051020&DB=&locale=en_EP
yeah - don't understand any of it, but will say what I always have - this is the real deal!!
Hi Suszianna
Yeah it is the real deal ! The patent mentions samples that are multiplexed (in rows and columns for multiple testing) which are Fluoresced with a laser beam and detector ! These are the very same descriptive words Professor Carl Smythe used in the Proactive Investor interviews to describe how the Paraytec Rapid 2 minute Covid-19 and other tests work BINGO !!!
BOOM BOOM BOOM
Yes it is dated 2005-10-20 It is well known that Paraytec have been developing this technology for a number of years now well before COVID-19 popped up its ugly head so this means we are not a one trick pony and our device has had many years head start on all other similar devices. The patents are in place , We know the device works ,we know it is the fastes and most accurate plus it can multi plex 100 tests at a time in a portable unit the size of a shoe box WOW .
We know that talks are in place to mass manufacture it and bring it to market THIS IS GOING TO BE MASSIVE
REMEMBER IT IS ADAPTABLE TO FIVE DIFFERENT LIFE SAVING EARLY DETECTION TESTS !!
Totally agree starknight. I think In the not too near future, I will be using the device for AD. Seem to be forgetful these days.
Even British Bulls has this down as a BUY .... :-0
£ in the days ahead
FIVE MAJOR PRODUCTS TO BE RELEASED and that is just from one of our sub companies PARAYTEC !
1. TWO MINUTE COVID-19 AND ALL VARIANTS RAPID SALIVA TEST
2. WORLD FIRST EVER RAPID BLOOD TEST FOR ALZHEIMERS DISEASE
3. NON INVASIVE URINE TEST FOR BLADDER CANCER (BEING SPUN OUT IN A NEW SUB COMPANY CALLED SENTINEL)
4. EARLY DETECTION OF SEPSIS IN BLOOD
5. EARLY DETECTION OF CANCER
And then we have other companies too
https://braveheartgroup.co.uk/investments/
What is not to like BUY BUY / HOLD HOLD ALL SHARES THIS IS GOING TO BE MASSIVE !!!
Busy at work at the moment but great to see we’ve reclaimed our board back....GLA and £1+ is just around the corner
Reposting for new investors GLA
Patents matter not when you have sold the business for billions and paid a £5 per share divi
feels like it's tick up time :))
Reposting for new investors GLA
Reposting for new investors GLA