Charles Jillings, CEO of Utilico, energized by strong economic momentum across Latin America. Watch the video here.
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Iamrich I agree re the percentage. I have tried to find the threshold criteria that this would need to meet to be approved. It usually has to be a percentage better than the current standard of care, so I dont think it would even need to be anywhere near 50%. Depends how the data is collated. From what I have read it will be assessed based on how each patient progresses, ie if a patient doesnt progress to need the next stage of treatment. So if for example 20% less patients who took the inhaler didnt then need to progress to a ventilator as compared to those on the placebo, that may be enough (and in terms of the numbers we have been looking at that would be a huge amount!).
My research so far hasnt found what the threshold would need to be but will try and find more info. I think the threshold is lower than you would expect, but happy to be proved wrong if anybody has further info on this?
Yheap get in tmrw while you can, Because the only news coming early will be good news, who knows what will happen this 4 day weekend, especially if things worsen here in the UK and USA looking bad every day,
Manifesto
I agree. Totally unique situation.
Patients are asked if they would like to be part of a trial as it is. Just keeping asking if they would like to be part of the long on going trials!
If it works of course.
Exciting day tomorrow gla
agree with all that fella. Expect a nice day again tomorrow and push over 70 with long weekend and no trading again until Tuesday.
Only positive coming out of SNG no negatives, also if there isnt any side effects I can see this being fast tracked and cutting short the trial dont get caught with your pants down, seller maybe gone this will climb to £1 now
Just my opinion and thats if SNT works 50% it will still get approved for the time being untill something better comes along as every one is far too behind and we need something now, so I think it will be a success even if it does half the job, and why im holding till approvals atleast,
Dont forget one thing is that DR's know how the body works and immune system and when this VIRUS broke out alot of the top drs were approaching SNG for their DRUGS, why because it matches the required medication for the problem at hand
Loads of reasons to suggest SNG works but of course until we get the trial results,
CEO seems confident meetings in regards to approvals
SNG have bought 4 miilion pounds worth of stock why? I am assuming they have been told by a approving body to stay ready to supply?
It is possible that if early results show that our inhaler
is definitely showing positive results compared to those
on the placebo, they can take the decision to give
all those on the trial the inhaler.....This does not
happen very often in trials, but when you consider
this unique situation and lack of other options
it could realistically be one potential outcome.......
Bodes well that was well tolerated in COPD/Asthma trials.
I would also be surprised if Dexamethasone shows good results. Whilst it may strengthen the lungs it is known to reduce the immune system. Immunotherapy trials in cancer have found that patients taking Dex were much less likely to be successful as are an immuno suppressant. Given the virus seems to affect people with a weakened immune system this may be an unwanted consequence of the drug...
Yheap looks like we are 1st in the race to come up with a treatmnt, All eyes will be on SNG,