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As you mentioned volatil1ty the same was observed for convalescent plasma (CP), but if I remember correctly it was also in immunocompromised individuals. If so isn’t it then rather caused by the immunocompromised condition as opposed to mAbs or CP and/or a combination of that?
The Beta variant was also believed to have originated from an individual who was immunocompromised.
some copies still there
https://thedailydan.tumblr.com/post/657994405473632256/yesterday-nbc-news-correspondent-ken-dilanian
Interesting on point b) in my post - all the news outlets that reported 'higher viral load' in vaccinated people have removed their news stories. Obvious some higher level government directive has asked to change messaging. Some will claim journalist errors in getting information wrong, some will say its a cover up. Either way I think damage is now done with claims of ADE.
Official messaging is now as per Fauci 'The level of virus in vaccinated persons is exactly the same as the level of virus in unvaccinated persons'
Fauci video - https://twitter.com/Poempieloempie1/status/1420470058980188166
Not just UK offcials that are crap at communication.
Maylia and other far East countries taking a beating at the moment together with Vietnam.
Olympics great news for the virus. Of course the games were not cancelled because of money and greed. The human race is a laugh a minute.
On a lighter note we have the imergence of a mutation called the Columbia variant. I watched a news report recently about the Colombian drug cartels struggling with exports of cocaine abroad. I mean you really couldn't make up, I suppose the cartels could go on furlough.
Thanks Joey
Good summary of the pertinent points
No doubt about its been a bad news week for vaccines knocking confidence in the general public. For many of us here there isn't any real surprises but for the general public they were sold on the vaccines being the silver bullett out the pandemic. Generally most Jo public were not aware of the difference between preventing/infection spread and reduction in severe disease.
Recent news
a) Double vaccinated people still get infected by SARS-COV-2 and spread it. Plenty of real world data from various countries showing between 20% and 50% efficacy.
b) CDC in USA (Confirmed by Fauci video) has identified vaccinated people have similar or higher amounts of vial load in the Nasopharynx as unvaccinated. Many scientists worried about first signs of ADE.
c) CDC on points a) and b) have responded by reversing policy on mask mandates and testing for vaccinated people. All vaccinated people now need to wear a mask and do regular testing again. Causing widespread anger in USA.
d) Phizer 6 month trial safety data shows 15 deaths in vaccine arm and 14 in the placebo arm. There was a small signal of elevated cardiac arrest in vaccine group 4 deaths compared to 1 in placebo.
e) Phizer says protection is waning from their own studies now 83.7% efficacy after 6 months and say a 3rd booster shot is necessary. However still claim 97% protection vs hospitalisation/death.
f) There is now a big push for 2nd generation vaccines that target nasal mucosal and upper respiratory tract which produce better protection against infection/spread by targeting areas of intial infection. Stimulating IgA response and related T cells is key, what current IM route vaccines lack.
g) Small Israel study shows 1 in 5 breakthrough cases in vaccinated people lead to Long Covid.
h) Fact checker websites have senior staff who are also on Phizer/Modernas board.
i) Scientists from round the world including CDC and SAGE are very worried they will see a vaccine escaping variant. This due to the high circulation of virus in society infecting a high % of people vaccinated.
j) Vaccine protection from hospitalisation/death in real world setting is still very high. Estimates between 85-95%.
Obviously this is more news based out of the USA and with a very politically charged country this news is being spun to suit agendas of pro vax or anti vax.
These are the facts though and why there are many questioning the vaccines.
They why invest and not spend all your life in the gym eating vegetables!
Get real
Having a chunk of money will be of little compensation if you are an unfortunate soul left with no quality of life or dead chum. Health is true Wealth need a head wobble I think.
The issue with efficacy numbers are that they can be easily manipulated.. I remember seeing the Israeli study that showed efficacy dropping below 60% for the 70+ after 4/5 months.. but when u take it all the age groups the efficacy increases to just under 90% at a 6 month mark, with a big drop followed after to low 80s and not enough data to show after what happens after that.. and that’s why booster shots are now necessary for the older age group and not for the younger group.. but politicians like to throw everyone in the same group so won’t surprise me if everyone will be made to get booster shots come autumn/winter and that when I am expecting a big mess..
I care as my guess is the vast majority do too
All this talk about who will get ill or who wont is just complete rubbish - We are all here to make money so who really cares what happens as long as SNG have a commercial product and get to sell it to the world and we all make MONEY.
Money and profit is the driver here.
So the young and fit can happily go visit granny, go unmasked wherever, incubate and release new variants to whoever they meet!
The way to stop a virus is to disrupt it's transmission - from everyone - not to give it a path to mutate and replicate.
Leave it to the experts.......
Therein displays the total misunderstanding!
Vaccines do not stop infection "one that stops infections and death at every age". What they do is train your immune system to recognise the virus and produce the antibodies required to defeat the virus before it does too much damage.
As for a vaccine that is as effective "at every age", biology just doesn't work that way.
Leave it to the experts, I say.
84% is a general figure but does not represent people over 50/60/70 and we all know the Pfizer has been given to the younger generation in the main so it’s a pointless %.
84% after 6 months is pretty impressive. Booster jabs are coming this autumn.
Pfizer jab just 84% effective after six months, data shows
The efficacy of the Covid-19 vaccine developed by Pfizer and BioNTech fell from 96% to 84% over six months, according to a preprint not yet peer-reviewed.