Rainbow Rare Earths sees competitive advantage in new separation technology for Phalaborwa project. Watch the full video here.
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I, therefore, reiterate that the currently observed convergence of naturally selected mutations towards S-derived antigenic sites that facilitate or are directly responsible for binding to the Ace-2 entry receptor combind with the velocity at which this evolution currently takes place poses a huge and imminent threat to the human population and will heavily backfire if we continue mass vaccination on a background of high viral infection rates while largely relaxing infection prevention measures.
Last but not least, it must be emphasized that those calling themselves ‘experts’ while pretending that this pandemic is ‘a pandemic among the non-vaccinated’ are devoid of any scientific insight in the evolutionary dynamics of Sars-CoV-2 as currently shaped by a combination of high viral infectivity and vaccine coverage rates. Neither the vaccinated (who merely believed the vaccine would protect them from Covid-19 disease) nor the non-vaccinated (who simply believe there is no need for them to take the vaccine in order to stay protected) are to be blamed for the escalation of this pandemic. Mass vaccination is the one and only culprit.
Note: A copy of this letter has been sent to WHO, NIH, CDC, the Bill & Melinda Gates Foundation, GAVI, CEPI, FDA, EMEA and to R&D leaders from Pfizer, Moderna, Astra-Zeneca, J&J, Novavax and GSK
Both, long-lived Sars-CoV-specific immunity acquired upon recovery from disease and innate, CoV-nonspecific Ab-mediated immunity normally contribute to establishing broadly protective herd immunity and thereby enable a natural CoV pandemic (or, for that matter, any pandemic of an acute, self-limiting viral disease) to eventually transition into an endemic phase. However, circulation of more infectious variants comes with a high price to pay for herd immunity to establish as high infectivity rates are more likely to erode natural, polyreactive (i.e., CoV-nonspecific) immunity in young and/ or healthy individuals. As a result, morbidity and hospitalization rates, and ultimately also the number of deaths, will increase. This self-amplifying cycle of enhanced viral infectiousness (resulting in enhanced viral infectivity rates) would only come to an end when the population density is diluted down to a level low enough for viral transmission (of a highly transmissible/ infectious variant!) to substantially diminish.
Whereas fast and dominant propagation of naturally selected, more infectious variants continues to erode the natural first line of variant-nonspecific immune defense in the non-vaccinated part of the population, vaccination of large parts of the population and contacts among vaccinated and non-vaccinated subjects are driving natural selection and adaptation of increasingly VI-escaping variants and are, therefore, increasingly compromising VMI. Neither previous CoV infection (including Sars-CoV-2 infection), nor higher vaccine coverage rates can compensate for the lost immunological capacity. Indeed, memory T cells elicited upon previous CoV infection or vaccination are not reportedly known to be endowed with cytotoxic activity towards CoV-infected cells, nor can S-specific Abs elicited upon previous CoV infection or vaccination prevent spreading of more infectious Sars-CoV-2 variants. Molecular epidemiologists have suggested that immune failure to block viral transmission (e.g., in immunosuppressed patients) causes variants to convergently evolve specifically selected mutations, thereby enabling escape from VMI. VI escape together with suppression of natural, CoV-nonspecific Abs by vaccinal Abs will make vaccinees highly susceptible to contracting Covid-19 disease.
Dominant propagation of more infectious viral variants could be mitigated by mass chemoprophylaxis using a potent antiviral. At the same time, immune pressure on vaccinal S-specific epitopes must be mitigated by calling an immediate halt to mass vaccination campaigns. Furthermore, early treatment of symptomatic subjects can prevent severe disease and provide them with durable protection against a diversified spectrum of more infectious variants and, thereby, also reduce viral transmission. However, this is the last opportunity to limit the disastrous consequences of mass vaccination
If it was a connection (however distanced) with the company then I hope they are nowhere near the tiller hehe.
Well whoever they have handed them to the Diggles and others so well done them and their market insight :)
Exactly and that's why it didn't look like him to me. Where did they sell? 18.75 or something?
I see it more as a chancer than anything else, but stranger things have happened.
Anyway all good FTB.
A last word of caution to all those pretending the Covid-19 pandemic is toning down
The current expansion in prevalence of infectious Sars-CoV-2 variants is highly problematic because it erodes natural Ab-based, variant-nonspecific immunity in the non-vaccinated part of the population. The high infectivity rate that results from this expansion not only further enhances the expansion of these variants but may also drive natural selection of viral variants that are featured by an even higher level of infectiousness. Erosion, therefore, of natural Ab-based, variant-nonspecific immunity promotes breeding and transmission of more infectious viral variants in the non-vaccinated part of the population. On the other hand, mass vaccination promotes natural selection of increasingly vaccine immunity (VI)-escaping variants in the vaccinated part of the population. Taken together, mass vaccination conducted on a background of high infectivity rates enables more infectious, increasingly VI-escaping variants to expand in prevalence. This evolution inevitably results in inclining morbidity rates in both, the non-vaccinated and vaccinated population and precipitates the emergence of circulating viral variants that will eventually fully resist vaccine-mediated immunity (VMI). This is why mass vaccination campaigns should not be conducted during a pandemic of a highly mutable virus, let alone during a pandemic of more infectious variants (unless transmission-blocking vaccines are used!). It is critical to understand that a rapid decline in viral infectivity rates that is not achieved by natural infection but merely results from expedited mass vaccination campaigns will only delay abrupt propagation of emerging, fully vaccine-resistant viral variants and hence, only delay the occurrence of a high wave of morbidity and mortality. In contrast, mass vaccination campaigns that are progressing more slowly, especially when conducted on a background of relatively low infectious pressure, will result in a steadily growing propagation of increasingly VI-escaping variants and hence, cause a wave of morbidity and mortality that continues to grow bigger and larger as more and more people become vaccinated. It’s only when fully vaccine-resistant viral variants will become dominant that this wave will start to peak.
To prevent more detrimental consequences of the ongoing evolution of Sars-CoV-2, we have no choice but to mitigate erosion of natural, Coronavirus (CoV)-nonspecific immunity in non-vaccinated individuals and exertion of strong immune selection pressure on immunodominant vaccinal epitopes in vaccinated individuals. This is to say that we must stop mass vaccination and lower viral infectivity rates immediately. Continued mass vaccination will only lead to a further increase in morbidity and hospitalization rates,
We know Evans is divesting in his orderly manner... or at least that was last message from him
Wonder who dumped the 185K during the day of the "Other" RNS re CH?
Bit of a mystery that.
Now THAT's a positive sign, but I still guess we'll not be allowed to fly just yet!
Good RNS though
Luc Montagnier is a French virologist and joint recipient, with Françoise Barré-Sinoussi and Harald zur Hausen, of the 2008 Nobel Prize in Physiology or Medicine for his discovery of the human immunodeficiency virus. He has worked as a researcher at the Pasteur Institute in Paris and as a full-time professor at Shanghai Jiao Tong University in China.
Montagnier said in part:
We’re in unknown territory and proclaim mandatory vaccines for everyone. It’s insanity. It’s vaccination insanity that I absolutely condemn.
He explained that he “is not looking for controversy, but for truth”.
Some of the points made in a clip of the interview translated exclusively for RAIR Foundation USA reveal that Prof. Montagnier is “outraged” that widespread vaccination of children could have horrific generational consequences.
He gives the example of the herbicide glyphosate, which can be passed on to future generations in a process known as “Transgenerational Epigenetic Inheritance.”
“Recent studies on glyphosate have shown that there are epigenetic effects,” Prof. Montagnier explained. “That means people who eat glyphosate in their diet pass on something that will affect future generations. Their children, their grandchildren, and great-grandchildren, they will suffer,” he continued.
The Nobel Laureate explained that the “Messenger RNA” may result in disastrous consequences without proper study. He said:
This Messenger RNA that’s being injected today in vaccines, may have effects on future generations that are undetected if we aren’t searching for them.
Another concern Montagnier expresses is the possibility of side effects of vaccines that could be seen in “five to ten years” related to “neurodegenerative illness.”
Neurodegenerative disease is “an umbrella term for a range of conditions which primarily affect the neurons in the human brain” and is described as “incurable and debilitating conditions that result in progressive degeneration and/or death of nerve cells.”
Montagnier states that there “are sequences that resemble the prion sequences in the RNA of the coronavirus” and could therefore “disorder the natural proteins in the brain, modifying them to make prions.”
A research article titled “RNA editing alterations define manifestation of prion diseases” explains that “Prion diseases are fatal neurodegenerative disorders characterized by rapidly progressive dementia.”
Talk about bringing the mood down.
Can we just have 5 mins to enjoy the fact that we have a trial approved before the zombie apocalypse arrives.
I thank you ............ Lol
Deadly Prion Brain Diseases & Experimental mRNA Jabs
An important and highly concerning study published early this year in the journal Microbiology & Infectious Diseases titled, “Covid-19 RNA Based Vaccines and the Risk of Prion Diseases,” addresses one of the many potential, unintended, adverse health effects of the experimental mRNA Covid-19 vaccines presently being deployed worldwide, namely, their possible induction of prion diseases, a category of highly fatal brain disorders.
The study abstract, well worth reading, summarizes both the context, intention, and results of the investigation:
“Development of new vaccine technology has been plagued with problems in the past. The current RNA based SARSCoV-2 vaccines were approved in the US using an emergency order without extensive long term safety testing. In this paper the Pfizer COVID-19 vaccine was evaluated for the potential to induce prion-based disease in vaccine recipients.
The RNA sequence of the vaccine as well as the spike protein target interaction were analyzed for the potential to convert intracellular RNA binding proteins TAR DNA binding protein (TDP-43) and Fused in Sarcoma (FUS) into their pathologic prion conformations. The results indicate that the vaccine RNA has specific sequences that may induce TDP-43 and FUS to fold into their pathologic prion confirmations.
In the current analysis a total of sixteen UG tandem repeats (?G?G) were identified and additional UG (?G) rich sequences were identified. Two GG?A sequences were found. Potential G Quadruplex sequences are possibly present but a more sophisticated computer program is needed to verify these. Furthermore, the spike protein, created by the translation of the vaccine RNA, binds angiotensin converting enzyme 2 (ACE2), a zinc containing enzyme.
This interaction has the potential to increase intracellular zinc. Zinc ions have been shown to cause the transformation of TDP-43 to its pathologic prion configuration. The folding of TDP-43 and FUS into their pathologic prion confirmations is known to cause ALS, front temporal lobar degeneration, Alzheimer’s disease and other neurological degenerative diseases.
The enclosed finding as well as additional potential risks leads the author to believe that regulatory approval of the RNA based vaccines for SARS-CoV-2 was premature and that the vaccine may cause much more harm than benefit. [emphasis added]“
Nobody can say with any certainty what is going to happen.The human race has been put through a massive experiment.
Only time will tell.
Wayne Rooney probably knows the answer to that
Another thought to chew on is this
What would be the greatest Trojan horse to inflict on mankind?
The great concern by people like Nobel prize winning Luc Montagnier, who co discovered the HIV virus, with the MRNA vaccine is that it delivers spike proteins into the body.
From the freedom of infomation act obtained in Japan about the Pfizer vaccine,it appears that they knew it does not stay only at the injection sites
Spike protein have been found in ovaries and other organs,they are also able to pass the blood brain barrier.
The great unknown with these experimental vaccines is could they cause a Prion BSE type mad cow disease or other diseases
Two weeks in mice is 18 months in humans,so we will not know for another 8 months or so.
We do need a modi1 update.... my feeling is that is now happening next year and there are valid scientific plus probably with Covidity running practical reasons.... however that is just a feeling from silence and on every conference blurb for this year modi1 trial is stated as going into the clinic 'next year'
They really need to update on the modi1 plans though..... modi2 looks to be in rapid development too...
Again these is also partnership potential there...my preferred route
You would hope every avenue is being used to speed up the process.
Yes, very plausible that the drug is on its way or its already there, we don't know it's all just conjecture.
It is great that things are moving on Covidity but I'm still waiting for the important news on the MODI 1 Trial Application / Approval.
That's why I'm invested in Scancell because when that is proven to have a high clearance rate, that will be the game changer in the fight against cancer.
I think it is worth mentioning the mRNAer's rely on lipid delivery.... it causes issues finite resources etc plus it is not quite clear if it could become something of a medical issue with repeated use..... experiment that especially now Israel is saying they need to do 3rd jabs already.....what id the lipids build up and cause probs or even themselves eventually trigger an immune response against them..
they will all be watching the scancell trial maybe not for the DNA but that non toxic simple peptide delivery.... as they can all replace the lipids with such a delivery
I detect this dreadful sniffiness by the old guard here.
Anyway the reality is Biontech only really started motoring with the development of is far from perfect first generation MRNA vaccine.
If Scancell's covidity does what it says on the tin,the incumbents could be toppled and the share price go up to 580 times higher.
Then there are all the other Scancell platforms.
Chester, I doubt vax is already there..imagine the disater if there was no or prolonged wait for approval ... plus the security issues there... It could now arrive fast though... might even be on its way in Sally Adams overnight bag lol
The 'colleagues' part will refer to Cape unis clinical trial team.... I have few doubts they are pros... like I say it'll be logistics now of getting things running... is the vax fully manufactured and non-injectable already? I'd think so... so it will be getting it all there ..... it could happen quite fast now
According to Lindy's statement we already have colleagues in SA.
If the our pathway follows previous urgent Covid trials we will already have a well planned route based on a positive approval outcome.
The hospital's will have been chosen and discussions held, the drug will already be in country and the trial paperwork already being raised.
I would think that the lessons learnt during this pandemic about speeding up all of the processes will be being used.
In answer to your question, BioNTech's revenues have come from licensing and collaborations. Prior to Covid - revenue for 2019 was over $100m. To date they must have received around half a billion dollars in licensing/collaboration payments with huge potential milestones lined up.
Even when operating as a privately held company they were no tiny bio with record breaking funding rounds - series A funding of $270m (led by Redmile incidentally) followed by a series B of $325. Then add in the grants - $445 million from the German Government, another $55m from Bill Gates. It goes on and on.
The only area in which BioNTech and Scancell are comparable is that they are both led by extraordinary scientists innovating at the cutting edge of science, but they are certainly not comparable when it comes to size and valuation.
Snooty Bermuda - it could be worse.
Morning. Crumbs. Linda’s words from the RNS yesterday…..
"We are very pleased that this CTA was approved so rapidly, reflecting the importance of the study in South Africa, and it is a testament to the dedication and professionalism of the Scancell team and our colleagues in Cape Town”.
Not sure of the context of “colleagues” when mentioned separately to “Scancell Team” but that may be just my interpretation.
Anyway, full steam ahead…..