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Anyone with any knowledge of the topic (ie not ideal speculation) have any idea how many prototypes Cytiva might have produced?
If they could produce 4,000 before the tech transfer / machine tooling from BBI and Abingdon it would help us really accelerate on these assessments but I have no real idea if they will have produce 50 prototypes for us or 10,000.
there was a newspaper article which stated that none of the companies developing the Vaccines will be held liable for anyone ill, or who dies, from the Vaccine they produce for Covid 19
being fair....would you or anyone you know take a vaccine that has been developed in 6 months..or less.
Any thoughts on this article today and implications for Avact Tests? i.e what happens if vaccine is approved before Avacta can get their test approved and onto the market???
https://www.ft.com/content/b782f666-6847-4487-986c-56d3f5e46c0b
It could be, but who would be 'they' in this instance? Public Health England + Oxford?
This government loves outsourcing to the private sector - and the explicit remit of the working group is to evaluate and triage the 'increasing number of commercial LFT's' - so while of course plausible, I'd be somewhat surprised...
Equally, your guess is as good as mine!
“Well despite my Avacta play treading water lately my other pharma play looks to have come good today it would appear. Still hoping Avacta comes out with something soon also....”
Yes there have been several in the covid space including ORPH.
For those looking for something else, a test that can detect cancer using autoantibodies 4 years before it manifests then check out ONC. Their lung cancer trial was the biggest P3 of its kind in the world and it’s just being commercialised. 4 Pharma majors signed up + NHS, US, Germany, UK distribution networks set up and China/Russia coming on next. They have much more as well + cash. 90m mcap.
Usual caveats but I do have several free or near free carries now and ONC has bagged once but got lots of legs.
Atb
Trek
From the LTF introduction:
"On ***15 August 2020***, DHSC Ministers commissioned PHE Porton Down to establish a time-limited SARS-CoV-2 test development and evaluation programme. A scientific team has been established to deliver this work in collaboration with the University of Oxford, PHE Porton Down’s external scientific advisors.
A delivery group, chaired by the Director of PHE Porton Down, will meet daily to direct and co-ordinate the programme. Oversight will be provided by Sir John Bell to ensure that it the work is carried out to appropriate quality and timeliness standards, and to whom progress will be reported at least weekly through an Oversight Group that he chairs."
I find this interesting as Avacta announced it's clinical validation partnership with LSTM on August 6th, nearly two weeks BEFORE the government established an LTF evaluation program.
We have heard it intimated from others (Ophidian et al) that new requirements from Porton Down have been imposed on LTF's as a consequence.
From that excerpt, we can tell this is a program of very high importance to ministers if the Director of Porton Down is to meet DAILY to review progress.
Draw your own conclusions but I don't really believe in coincidences - I suspect this is likely the root of the perceived delay: Avacta are ahead of the government on test development, who have subsequently requested design changes while also holding the company under NDA to allow the Whitehall gears to turn...
That question cannot be answered at the moment. Neither can the converse question be answered ie. will vaccine research become irrelevant due to next generation testing regimes being preferred? Consensus view at the moment is that vaccines & tests will BOTH be needed for an effective control regime to be successful. Far too early to say though.
No
Nice find Manc, if only to get a better feel for the testing process prior to procurement, and the time taken to complete each evaluation.
Will Covid 19 testing become irrelevant as UK government to agree Covid 19 challenge trials at UK lab owned by Hvivo to accelerate vaccine development..
https://www.mirror.co.uk/news/politics/uk-deliberately-infect-volunteers-coronavirus-22730802
Well despite my Avacta play treading water lately my other pharma play looks to have come good today it would appear. Still hoping Avacta comes out with something soon also....
Humans will be deliberately infected with the coronavirus as Britain holds the world's first Covid-19 human challenge trials, it is reported.
Volunteers are to be deliberately infected with the new coronavirus to assess the effectiveness of experimental vaccines and to speed up Britain's delivery of the vaccine, the Financial Times reported on Wednesday, citing people involved in the project. The government-funded project is expected to begin in January at a quarantine facility in London, the report said.
Volunteers will be first inoculated with a vaccine and later receive a challenge dose of the coronavirus. The vaccine to be tested in the project has not been named, but the clinic earmarked for the initial challenge trials is said to be run by London-based hVivo.
Updated today - How the government assesses offers of COVID-19 tests from developers for procurement and use in the UK. https://www.gov.uk/government/publications/assessment-and-procurement-of-coronavirus-covid-19-tests?utm_source=2b774cfd-1206-4a86-a4a2-600bcf756c70&utm_medium=email&utm_campaign=govuk-notifications&utm_content=immediate