Issue of Equity & Total Voting Rights

Instem plc("Instem" or the "Company")

Issue of Equity and Total Voting Rights

Instem plc (AIM: INS), a leading provider of IT solutions and services to the global life sciences market, announces that, following the exercise of vested EMI share options, 20,000 ordinary shares of 10p each in the Company ("Ordinary Shares") have been issued.

Application has been made to the London Stock Exchange for the admission of the 20,000 new Ordinary Shares to trading on AIM. Admission is expected to take place at 8.00am on 4 October 2017.

Total Voting Rights

Following the issue and allotment of the above New Ordinary Shares, the Company's issued share capital will comprise of 15,886,660 Ordinary Shares. The Company does not hold any Ordinary Shares in treasury. Therefore the total number of voting rights in the Company is 15,886,660.

The figure of 15,886,660 may be used by shareholders as the denominator for the calculations by which they will determine if they are required to notify their interest in, or a change of their interest in, the Company under the FCA's Disclosure Guidance and Transparency Rules.

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About Instem 

Instem is a leading provider of IT solutions & services to the life sciences market delivering compelling solutions for Study Management and Data Collection; Regulatory Solutions for Submissions and Compliance; and Informatics-based Insight Generation.

Instem solutions are in use by customers worldwide and enable our clients to bring life enhancing products to market faster.

Instem's portfolio of software solutions increases client productivity by automating study-related processes while offering the unique ability to generate new knowledge through the extraction and harmonisation of actionable scientific information.

Instem supports over 500 clients through offices in the United States, United Kingdom, France, Japan, China and India.

To learn more about Instem solutions and its mission, please visit instem.com.