Smith & Nephew Regulatory News (SN.)

12 August 2022

Smith & Nephew plc

Transaction in Own Shares

Smith & Nephew plc (the "Company") announces today it has purchased the following number of its own ordinary shares of US 20¢ each through JP Morgan, as part of its USD $125 million share buyback programme announced on 08 August 2022 and in accordance with the authority granted by shareholders at the Company's Annual General Meeting on 13 April 2022.

Aggregated details of share purchase transactions according to trading venue are set out below:

The Company intends to hold these shares in Treasury and then cancel them or allocate them to employee share awards as they fall due.

Since 9 August 2022, the Company has purchased 1,923,363 shares at a cost (including dealing and associated costs) of £20,554,440.80.

Following the purchase of these shares, the Company holds 6,954,219 of its shares in Treasury. The Company's issued share capital, with one voting right per share consists of 870,607,814 ordinary shares of US20¢ each (excluding treasury shares). This figure of 870,607,814 is the figure which should be used by shareholders as the denominator when determining whether they are required to notify their interest in, or a change to their interest in, the Company under the FCA's Disclosure Guidance and Transparency Rules.

These purchases were made by JP Morgan on behalf of the Company.

This announcement is made in accordance with the requirements of LR 12.4.6.

In accordance with Article 5(1)(b) of Regulation (EU) No 596/2014 (as incorporated into UK domestic law by the European Union (Withdrawal) Act 2018), a full breakdown of the individual purchases is attached to this announcement.

http://www.rns-pdf.londonstockexchange.com/rns/9268V_1-2022-8-12.pdf

Sarah Carne

Deputy Company Secretary

Smith & Nephew plc

Tel: +44 (0)1923 477100