The next focusIR Investor Webinar takes place tomorrow with guest speakers from WS Blue Whale Growth Fund, Taseko Mines, Kavango Resources and CQS Natural Resources fund. Please register here.

Less Ads, More Data, More Tools Register for FREE

Pin to quick picksScancell Holdings Regulatory News (SCLP)

Share Price Information for Scancell Holdings (SCLP)

London Stock Exchange
Share Price is delayed by 15 minutes
Get Live Data
Share Price: 9.875
Bid: 9.50
Ask: 10.25
Change: 0.00 (0.00%)
Spread: 0.75 (7.895%)
Open: 9.875
High: 9.875
Low: 9.875
Prev. Close: 9.875
SCLP Live PriceLast checked at -

Watchlists are a member only feature

Login to your account

Alerts are a premium feature

Login to your account

Vesting of Ichor Options

25 May 2012 07:00

RNS Number : 0809E
Scancell Holdings Plc
25 May 2012
 

 

25 May 2012

 

 

 

Scancell Holdings Plc

('Scancell' or the 'Company')

 

Vesting of Ichor Options

 

Scancell Holdings Plc, (AIM: SCLP), the developer of therapeutic cancer vaccines, announces that, further to the commencement of the Phase II clinical trial for SCIB1, the Company's first cancer vaccine which is being developed for the treatment of melanoma, 3,184,620 options previously granted to ICHOR Medical Systems Inc ('ICHOR') have now vested.

 

As announced on 10 July 2010, ICHOR was granted options over a total of 7,961,560 ordinary shares in the Company (as adjusted for the subdivision of the Company's share capital announced on 30 June 2011). The subscription price payable upon exercise of the options is 4.5p per share. The options were originally granted under a License and Supply Agreement ('the Agreement') dated 13 July 2009 made between Scancell and ICHOR.

 

Under the terms of the Agreement, ICHOR agreed to supply its TriGrid™ electroporation device for Scancell's pre-clinical and clinical studies with SCIB1 and gave Scancell an option to license TriGrid™ for commercial use on achievement of certain milestones and payment of royalties.

 

In return, ICHOR was granted options to subscribe for ordinary shares in the Company. The options vest as follows: 1,592,310 options vested on regulatory approval being granted to start clinical trials in the UK (which has already occurred); 3,184,620 options vested on starting the first Phase II clinical trial (which has recently occurred); and 3,184,630 options will vest on completing the first Phase II clinical trial. Each tranche of the options may be exercised at any time in the five year period after the relevant vesting date.

A copy of this announcement is available for download on the Company's website at http://www.scancell.co.uk/

 

 

-ENDS-

For further information contact:

 

Professor Lindy Durrant/Dr Richard Goodfellow

Scancell Holdings Plc

+ 44 (0)207 653 9850

Graham Herring/ Heather Armstrong

Newgate Threadneedle

+ 44 (0)207 653 9850

 

Ross Andrews/Tom Rowley

 

Zeus Capital

+ 44 (0)161 831 1512

 

 

 

About Scancell

 

Scancell is developing novel therapeutic vaccines for the treatment of cancer and infectious diseases based on its groundbreaking ImmunoBody® technology platform. Scancell's first cancer vaccine, SCIB1, is being developed for the treatment of melanoma and is in Phase II clinical trials.

 

Treating cancer by vaccination allows small non-toxic doses of a vaccine to be administered to a patient, stimulating an immune response. Effective cancer vaccines need to target dendritic cells to stimulate both parts of the cellular immune system; the helper cell system where inflammation is stimulated at the tumour site; and the cytotoxic T-lymphocyte or CTL response where immune system cells are primed to recognise and kill specific cells.

 

A limitation of many cancer vaccines currently in development is that they cannot specifically target dendritic cells in vivo. Several groups have demonstrated successful vaccination by growing dendritic cells ex vivo, pulsing them with tumour antigens and re-infusing them. However, this procedure is patient specific, time consuming and expensive. Scancell has developed its breakthrough patent protected ImmunoBody® technology to overcome these limitations.

 

An ImmunoBody® is a DNA vaccine encoding a human antibody or fusion protein engineered to express helper cell and CTL epitopes from tumour antigens over-expressed by cancer cells. Antibodies are ideal vectors for carrying T cell epitopes from tumour antigens as they can effectively target dendritic cells via their Fc receptors, allowing efficient stimulation of high avidity and high frequency helper and CTL responses.

 

The ImmunoBody® technology can be adapted to provide the basis for treating any tumour type and may also be of potential utility in the development of vaccines against hepatitis, HIV and other chronic infectious diseases.

 

 

 

About Ichor Medical Systems

 

Ichor Medical Systems' TriGrid™ Delivery System (TriGrid) is the first integrated and fully automated device for electroporation-mediated DNA administration in humans. Ichor, a privately-held biotech company based in San Diego, CA, is collaborating with partners on four continents to provide its enabling TriGrid platform as a means for delivery of DNA drugs and vaccines in disease indications such as melanoma, malaria, hepatitis B virus (HBV) infection, human immunodeficiency virus (HIV) infection, melanoma, Alzheimer's disease, and others. For further information, visit www.ichorms.com.

 

This information is provided by RNS
The company news service from the London Stock Exchange
 
END
 
 
MSCPGUAPAUPPGQC
Date   Source Headline
9th May 20247:00 amRNSScancell presenting at 21st CIMT Annual Meeting
17th Apr 20247:00 amRNSPresenting at the Annual Immuno-Oncology Summit
16th Apr 20247:00 amRNSBlock Listing Six Monthly Return
3rd Apr 20247:00 amRNSEmployee exercise of share options
2nd Apr 20247:00 amRNSScancell to Present at 2024 AACR Annual Meeting
28th Mar 20241:21 pmRNSScancell Appoints WG as Joint Broker
26th Mar 202412:22 pmRNSFirst iSCIB1+ patient dosed
14th Mar 202411:17 amRNSAppointment of Sath Nirmalananthan to the Board
12th Mar 20247:00 amRNSScancell Attendance at Upcoming Conferences
4th Mar 20247:00 amRNSPresenting at Next-Gen Immuno-Oncology Conference
20th Feb 20247:00 amRNSChange of Auditor
5th Feb 20247:00 amRNSDirectorate Change
30th Jan 20247:00 amRNSInterim Results
26th Jan 20247:00 amRNSNotice of Interim Results and Presentation
17th Jan 20241:46 pmRNSUpdate on SCOPE trial
28th Dec 20235:36 pmRNSHolding(s) in Company
27th Dec 202311:38 amRNSHolding(s) in Company
19th Dec 20237:00 amRNSResult of the Open Offer
6th Dec 202312:41 pmRNSPDMR Notification
1st Dec 20237:00 amRNSResults of Placing
30th Nov 20235:03 pmRNSProposed Capital Raise to raise approximately £6m
29th Nov 20232:35 pmRNSResult of AGM
28th Nov 20237:00 amRNSUpdate on SCOPE trial
10th Nov 20238:32 amRNSScancell to present at 20th SMR Congress
1st Nov 20237:00 amRNSScancell to present at 38th Annual SITC meeting
31st Oct 202312:00 pmRNSNotice of AGM
31st Oct 20237:00 amRNSResults for the Year Ended 30 April 2023
20th Oct 20237:00 amRNSUpdate on Final Results
18th Oct 20237:00 amRNSScancell to speak at World Vaccine Congress Europe
17th Oct 20237:00 amRNSBlock Listing Six Monthly Return
11th Oct 20237:00 amRNSChange of Date for Final Results
3rd Oct 20237:00 amRNSNotice of Final Results and Investor Presentation
19th Sep 20237:00 amRNSPositive data from Phase 2 SCOPE trial with SCIB1
14th Sep 20237:00 amRNSScancell to present three posters at ICI
7th Sep 20237:00 amRNSScancell Appoints Head of Business Development
29th Aug 20237:00 amRNSScancell Appoints Sath Nirmalananthan as CFO
31st Jul 20237:00 amRNSModi-1 trial open for expansion in CPI combination
13th Jul 20239:14 amRNSExtension of exercise period for CEO share options
10th Jul 20237:00 amRNSPipeline strategy and business update
2nd Jun 20237:00 amRNSScancell to Present Modi-1 Data at ASCO
21st Apr 20237:00 amRNSIssue of share options to Non-Executive Directors
18th Apr 20237:00 amRNSModiFY Phase 1/2 poster presentation at AACR 2023
17th Apr 20237:00 amRNSBlock Listing Application to AIM
13th Mar 20237:00 amRNSStatement re: Silicon Valley Bank (SVB)
21st Feb 20239:05 amRNSSecond Price Monitoring Extn
21st Feb 20239:00 amRNSPrice Monitoring Extension
21st Feb 20237:00 amRNSEncouraging early efficacy data from ModiFY trial
13th Feb 20237:00 amRNSPositive response in COVIDITY trial
8th Feb 20237:00 amRNSIssue of Equity
1st Feb 20237:00 amRNSDr Jean-Michel Cosséry appointed as Chairman

Due to London Stock Exchange licensing terms, we stipulate that you must be a private investor. We apologise for the inconvenience.

To access our Live RNS you must confirm you are a private investor by using the button below.

Login to your account

Don't have an account? Click here to register.

Quickpicks are a member only feature

Login to your account

Don't have an account? Click here to register.