Sant Uk.10te% Regulatory News (SAN)

Abbey National Treasury Services plc(incorporated in England and Wales with registered number 2338548)

and

SANTANDER UK PLC(incorporated in England and Wales with registered number 2294747)

NOTICE OF Substitution of Issuer

to the holders of:

Series 858 USD750,000 Capital-at-risk Equity Index Linked Automatic Early Redemption Notes due November 2019 (ISIN: XS0962314406)

Series 859A "Bermudan Style" Put Warrants Linked to an Equity Index (ISIN: GB00BCZTGY18)

Series 859B "Bermudan Style" Call Warrants Linked to an Equity Index (ISIN: GB00BCZTGX01)

Series 878A "Bermudan Style" Put Warrants Linked to an Equity Index (ISIN: GB00BFH59503)

Series 878B "Bermudan Style" Call Warrants Linked to an Equity Index (ISIN: GB00BFH59495)

Series 879 GBP750,000 Capital-at-risk Equity Index Linked Automatic Early Redemption Notes due December 2019 (ISIN: XS0978112539)

Series 907 GBP800,000 Capital-at-risk Equity Index Linked Automatic Early Redemption Notes due February 2020 (ISIN: XS0997949416)

Series 908A "Bermudan Style" Put Warrants Linked to an Equity Index (ISIN: GB00BGSGSW99)

Series 908B "Bermudan Style" Call Warrants Linked to an Equity Index (ISIN: GB00BGSGSX07)

Series 909 GBP700,000 Capital-at-risk Equity Index Linked Automatic Early Redemption Notes due February 2020 (ISIN: XS0997949507)

Series 910A "Bermudan Style" Put Warrants Linked to an Equity Index (ISIN: GB00BGSGTB51)

Series 910B "Bermudan Style" Call Warrants Linked to an Equity Index (ISIN: GB00BGY6WQ50)

Series 993 EUR1,735,000 Equity Index Linked Notes due May 2018 (ISIN: DE000A1ZK210)

Series 1004 GBP2,150,000 Capital-at-risk Equity Index Linked Automatic Early Redemption Notes due October 2020 (ISIN: XS1089212341)

Series 1005 "Bermudan Style" Call Warrants Linked to Equity Indices (ISIN: GB00BP856812)

Series 1006 GBP 2,350,000 Capital-at-risk Equity Index Linked Automatic Early Redemption Notes due October 2020 (ISIN: XS1089212697)

Series 1007 "Bermudan Style" Call Warrants Linked to Equity Indices (ISIN: GB00BP856473)

Series 1012 GBP2,195,000 Capital-at-risk Property Index Linked Notes due October 2020 (ISIN: S1097313743)

Series 1015 EUR458,000 Equity Index Linked Notes due July 2018 (ISIN: DE000A1ZNBR8)

Series 1032 GBP1,400,000 Capital-at-risk Equity Index Linked Automatic Early Redemption Notes due November 2020 (ISIN: XS1113138900)

Series 1033 "Bermudan Style" Call Warrants Linked to Equity Indices (ISIN: GB00BQXKRH45)

Series 1036 GBP620,000 Capital-at-risk Equity Index Linked Automatic Early Redemption Notes due November 2020 (ISIN: XS1113140047)

Series 1037 "Bermudan Style" Call Warrants Linked to Equity Indices (ISIN: GB00BQXKRG38)

Series 1074 GBP960,000 Capital-at-risk Equity Index Linked Automatic Early Redemption Notes due April 2021 (ISIN: XS1196273541)

Series 1075 "Bermudan Style" Call Warrants Linked to Equity Indices (ISIN: GB00BVZHXD62)

Series 1107 GBP1,000,000 Variable Interest Rate and Equity Index Linked Automatic Early Redemption Notes due April 2023 (ISIN: XS1580143516)

Series 1112 GBP2,200,000 Variable Interest Rate and Equity Index Linked Automatic Early Redemption Notes due July 2024 (ISIN: XS1616810328)

Series 1115 GBP500,000 Variable Interest Rate and Equity Index Linked Automatic Early Redemption Notes due September 2024 (ISIN: XS1649341440)(together, the "Securities")

each issued by Abbey National Treasury Services plc under itsProgramme for the issuance of Notes, Certificates and Warrantsunconditionally and irrevocably guaranteed by Santander UK plc

NOTICE IS HEREBY GIVEN that, with effect on and from 1 November 2017 (the "Effective Date") Santander UK plc will be substituted in place of Abbey National Treasury Services plc as principal obligor under the Securities. This substitution will be effected pursuant to a deed of substitution, novation and amendment dated 16 October 2017 entered into between, inter alios, Abbey National Treasury Services plc as original issuer, Santander UK plc as new issuer, and Citibank N.A. as principal paying agent (the "Deed of Substitution, Novation and Amendment").

On and from the Effective Date, the Securities will be the sole liability of Santander UK plc and will not be guaranteed by any other entity in the Santander UK group.

Copies of the Deed of Substitution, Novation and Amendment are available for inspection from the principal paying agent whose address is:

Citibank N.A.Citigroup Centre

Canada Square

Canary Wharf

London

E14 5LBUnited Kingdom

For further information regarding the matters set out in this notice, please contact:

Structured Notes DeskSantander UK plc2 Triton SquareRegent's PlaceLondon NW1 3AN

Tel: +44 (0) 20 7756 7000

Email: structurednotesafm@santander.co.uk

This notice does not constitute or form part of an offer to sell or the solicitation of an offer to subscribe for or otherwise acquire any securities.