Last checked at 22 Dec 2015 12:08
Physiomics plc
(the "Company" or "Physiomics")
Issue of Options
The Company confirms that it has agreed to issue share options to each of its directors, as follows:
1. 64,523,106 share options over ordinary shares in the Company ("Share Options") have been granted to each of Mark Chadwick and Christophe Chassagnole under the Enterprise Management Initiative Scheme ("EMI"). The options are exercisable at a price of 0.035p each (being the average mid-market closing price for the three days prior to the date of issue).
2. A total of 25,809,242 share options over ordinary shares in the Company ("Additional Share Options") have been granted to Paul Harper under an Unapproved Share Option Scheme. The options are exercisable at a price of 0.035p each.
The options vest after 3 months and can be exercised within 10 years of the date of grant.
If both the Share Options and Additional Shares Options were to be exercised, they would represent 4.45% of the fully diluted, issued share capital of the Company.
Following this issue, Mark Chadwick and Christophe Chassagnole will each hold options over 137,936,532 ordinary shares in the Company and Paul Harper will hold options over 55,174,612 share options ordinary shares in the Company in accordance with the table below.
Share Options |
| ||||||
Award no. | Granted | Exercise price | Expiry date |
| |||
p | |||||||
Paul Harper | 1 | 2,327,710 | 0.15 | 18-Dec-18 | |||
2 | 7,664,541 | 0.40 | 28-Feb-20 | ||||
3 | 1,293,250 | 0.34 | 08-Nov-21 | ||||
4 | 5,175,248 | 0.132 | 11-Feb-23 | ||||
5 | 12,904,621 | 0.062 | 23-Mar-25 | ||||
6 | 25,809,242 | 0.035 | 20-Dec-25 | ||||
Christophe Chassagnole | 1 | 7,499,453 | 0.383 | 06-Sep-17 | |||
2 | 5,624,590 | 0.15 | 18-Dec-18 | ||||
3 | 11,856,584 | 0.40 | 28-Feb-20 | ||||
4 | 3,233,125 | 0.34 | 08-Nov-21 | ||||
5 | 12,938,121 | 0.132 | 11-Feb-23 | ||||
6 | 32,261,553 | 0.062 | 23-Mar-25 | ||||
7 | 64,523,106 | 0.035 | 20-Dec-25 | ||||
Mark Chadwick | 1 | 19,984,500 | 0.27 | 05-Dec-20 | |||
2 | 3,233,127 | 0.34 | 08-Nov-21 | ||||
3 | 4,996,125 | 0.293 | 18-Dec-21 | ||||
4 | 12,938,121 | 0.132 | 11-Feb 23 | ||||
5 | 32,261,553 | 0.062 | 23-Mar-25 | ||||
6 | 64,523,106 | 0.035 | 20-Dec-25 | ||||
Enquiries:
Physiomics plc
Mark Chadwick
+44 (0)1865 784980
WH Ireland Limited
Katy Mitchell
+44 (0) 161 832 2174
About Physiomics plc
Physiomics (AIM:PYC) is a computational systems biology services company applying simulations of cell behaviour to drug development to reduce the high attrition rates of clinical trials. 80-90 per cent of all clinical drug candidates fail to reach the market and estimates show that an overall ten per cent improvement in success rates could reduce the cost of one drug's development by as much as $242 million, from the current estimate of around $800 million1.
Physiomics develops computational systems biology models to predict and understand cancer drug efficacy from pre-clinical research to clinical development. Physiomics has created detailed mathematical models incorporating the most important molecular events taking place during the human cell cycle and apoptosis processes. The company's SystemCell® technology enables the simulation of populations of "virtual cells". The company has also developed a "Virtual Tumour" model to simulate the effect of anti-cancer drugs on tumour growth. The models are used to optimise compound design and to design drug schedules and combination therapies.
Physiomics, based in Oxford, UK, was founded in 2001, and floated on AIM in 2004. For further information, please visit www.physiomics-plc.com
SystemCell® is a registered trademark of Physiomics plc
1Tufts Centre Impact Report 2002