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Service Agreement with Onconome Inc.

18 Apr 2007 08:30

Proteome Sciences Plc ("the Company")

18 April 2007

Onconome Inc. to Use ProteoSHOP‚® for Cancer Biomarkers

Proteome Sciences plc ("Proteome") is pleased to announce that it is to apply its ProteoSHOP‚® proteomics toolbox to analyse prostate and colon cancer materials provided by Seattle based Onconome Inc. ("Onconome").

Proteome has a strong track-record in the discovery and validation of cancer biomarkers and will apply its 2-dimensional gel western blotting technology to further characterise diagnostic antibodies developed by Onconome for the diagnosis and prognostic monitoring of patients with prostate and colon cancers. In addition Proteome will perform new biomarker discovery using Onconome's materials on its high-throughput 2-dimensional gel electrophoresis platform and using its patented isobaric Tandem Mass Tags‚® for gel-free analyses.

Under the terms of the collaboration Proteome will receive research funding for the provision of ProteoSHOP‚® services.

Commenting on the collaboration H. Raymond Cairncross, Co-Founder and Chief Executive Officer of Onconome Inc. said:

"As a company dedicated to the discovery, development and commercialization of protein biomarkers for the early detection of prostate, colon and other types of cancers and life-threatening diseases, it is critical that we collaborate with companies highly skilled and experienced in the proteomics field. We feel we have found such a partner in Proteome Sciences and look forward to a mutually productive and profitable relationship."

Commenting on the collaboration Christopher Pearce, Chief Executive of Proteome Sciences said:

"We are pleased to announce this ProteoSHOP‚® deal building on the technological and commercial progress made in the last 12 months. Our unique combination of proteomics solutions for biomarker discovery and validation, linked to our considerable experience in oncology provides Onconome with access to the tools needed for further characterisation of their prostate and colon cancer biomarkers.

This collaboration reflects a growing need within the diagnostics and pharmaceutical industries for external sourcing of well characterised and validated protein biomarkers which ProteoSHOP‚® was designed to support. With a portfolio of well characterised biomarkers across a range of diseases and the patented technologies within ProteoSHOP‚® we are ideally placed to become the partner of choice for protein biomarker discovery projects."

EndsNotes to editors:Proteome Sciences plc

Proteome Sciences, a global leader in applied proteomics, uses high sensitivity proprietary technologies to detect differentially expressed proteins in diseases. The protein biomarkers discovered in body fluids or tissues are validated, developed and commercialised as diagnostic, prognostic or therapeutic products through strategic alliances and out-licensing.

Through its unique ProteoSHOP‚® toolbox, Proteome Sciences provides high sensitivity/high throughput proteomics solutions, including traditional two dimensional gel-based electrophoresis (2DE) and proprietary gel-free protein sequence tag technologies (PST‚®, qPST¢â€ž¢& TMT‚®), to major pharma, biotechnology and diagnostic companies, to discover and exploit protein biomarkers. Sensitizer‚® chemical mass tags have been developed separately as a series of stand-alone reagents.

For further information please visit www.proteomics.com.

Proteome Sciences plc

Dr. Ian Pike, Business Development DirectorEmail: ian.pike@proteomics.comChristopher Pearce, Chief Executive OfficerEmail: christopher.pearce@proteomics.com

Tel: +44 (0)1932 865065

Onconome, Inc.

Onconome, Inc. (Seattle, WA) was incorporated in 2000 as a biomedical company committed to the discovery and commercialization of products for the early detection of prostate, colon, and other types of cancer and life-threatening human diseases. Through its licensing arrangements with both Johns Hopkins University School of Medicine and the University of Pittsburgh, Onconome has obtained exclusive, worldwide rights to the use and development of numerous protein markers for the early diagnosis of cancer as well as for drug screening and in vivo imaging. Under a Contract Research Agreement, Onconome funds the discovery and development of these biomarkers at Johns Hopkins. University.

For more information, visit the company's Web site at www.onconome.com

Onconome, Inc.

Erick Rabins, Managing Director, Business Development Email: erabins@onconome.com

Ray Cairncross, Co-Founder & Chief Executive Officer Email: rcairncross@onconome.com

Tel: 206-268-3500

Public Relations for Proteome Sciences

IKON Associates

Adrian Shaw Tel: +44 (0)1483 535102Mobile: +44 (0)797 9900733Email: adrian@ikonassociates.com

PROTEOME SCIENCES PLC
Date   Source Headline
26th Apr 20247:00 amRNSContract Win
10th Apr 20247:00 amRNSFinal Results
2nd Jan 20247:00 amRNSCompletion of new facility in San Diego
30th Nov 20237:00 amRNSTrading Update
2nd Oct 20237:00 amRNSLaunch of Single Cell Proteomics Services
30th Aug 20232:14 pmRNSInvestor Presentation
25th Aug 20237:00 amRNSInterim Results
1st Jun 20239:43 amRNSRepayment of Loan
17th May 20231:05 pmRNSResult of AGM
17th May 20237:00 amRNSAGM Statement
12th May 20237:00 amRNSExpansion into the US
14th Apr 202310:45 amRNSDirector/PDMR Shareholding
6th Apr 202311:34 amRNSDirector/PDMR Shareholding
6th Apr 202310:30 amRNSInvestor Presentation
4th Apr 20237:00 amRNSFinal Results
29th Mar 20237:00 amRNSNotice of Results
6th Mar 20234:35 pmRNSPrice Monitoring Extension
20th Feb 20237:00 amRNSTrading Update
5th Jan 20237:00 amRNSMilestone Payment for TMT®/TMTpro™ Sales
1st Dec 20224:38 pmRNSGrant of Options and PDMR/director shareholdings
12th Oct 20227:00 amRNSGrant of Options and PDMR/director shareholdings
4th Oct 20227:00 amRNSChange of Auditor
20th Sep 20224:40 pmRNSSecond Price Monitoring Extn
20th Sep 20224:35 pmRNSPrice Monitoring Extension
18th Aug 20227:00 amRNSAppointment of Chief Financial Officer
11th Aug 20227:00 amRNSInvestor Presentation
4th Aug 20227:00 amRNSInterim Results
3rd Aug 20227:00 amRNSMilestone towards Single Cell Proteomics services
26th May 20229:04 amRNSChange of Registered Office
16th May 20221:24 pmRNSResult of AGM
16th May 20227:00 amRNSAGM Statement
12th May 20227:00 amRNSSubstantial Contract Win
26th Apr 20224:45 pmRNSDirector/PDMR Shareholding
21st Apr 20225:13 pmRNSDirector/PDMR Shareholding
11th Apr 20227:00 amRNSInvestor Presentation
1st Apr 20226:01 pmRNSDirector shareholding
31st Mar 20227:09 amRNSFinal Results
30th Mar 202211:24 amRNSLoan amendment
29th Mar 20227:00 amRNSNotice of Results
16th Feb 20224:40 pmRNSSecond Price Monitoring Extn
16th Feb 20224:35 pmRNSPrice Monitoring Extension
3rd Feb 20227:00 amRNSTrading Update
31st Dec 202112:36 pmRNSPrice Monitoring Extension
20th Dec 20217:00 amRNSSubstantial Contract Win
9th Dec 20214:41 pmRNSSecond Price Monitoring Extn
9th Dec 20214:36 pmRNSPrice Monitoring Extension
29th Nov 20214:36 pmRNSPrice Monitoring Extension
26th Nov 20214:36 pmRNSPrice Monitoring Extension
5th Nov 20217:00 amRNSPRM,INmune Bio presenting biomarker discovery data
3rd Nov 20214:41 pmRNSSecond Price Monitoring Extn

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