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Conversion of Convertible Loan Notes

6 May 2026 07:00

RNS Number : 1272D
Cizzle Biotechnology Holdings PLC
06 May 2026
 

6 May 2026

Cizzle Biotechnology Holdings plc

("Cizzle", "Cizzle Biotechnology", or the "Company")

Conversion of Convertible Loan Notes

Cizzle Biotechnology, the UK based diagnostics developer of early cancer tests, announces that the Company has received a notice to convert £400,000 of convertible loan notes ("CLNs") held by Frazer Lang (registered in the name of Ropemaker Nominees Limited) (the "Note Holder"), an existing investor in the Company.

On 20 May 2025, the Company secured funding of £150,000 through the issue of CLNs to Frazer Lang and the funding provided by him was extended though the issue of further CLNs of £250,000 on 5 November 2025. The CLNs are convertible at the election of the Note Holder into new ordinary shares of 0.01p in the Company ("Ordinary Shares") at a price of 1.4 pence per Ordinary Share. Following receipt of the conversion notice the Company will therefore issue 28,571,429 new Ordinary Shares ("Conversion Shares") to the Note Holder.

In addition, the Company announced on 2 April 2026 that it has entered into a new facility to provide the Company with up to £250,000 through the potential issue of further unsecured convertible loan notes ("Facility Notes") to the Note Holder. The Facility Notes can be drawn down, at the sole election of the Company as to £100,000 on 1 May 2026, £100,000 on 1 June and £50,000 on 1 July 2026. The Facility Notes are convertible at 1.4 pence per Ordinary Share at any time up to 30 October 2026. The Company has now drawn down £100,000 of the Facility Notes and following completion of the £400,000 CLN conversion, the Note Holder will hold £100,000 of CLNs.

Admission and Total Voting Rights

Application will be made for the 28,571,429 Conversion Shares to be admitted to trading on the Main Market of the London Stock Exchange and to listing on the FCA Official List ("Admission"). It is expected that the issue of the 28,571,429 Conversion Shares will take place, Admission will become effective and that dealings in the Conversion Shares on the Main Market of the London Stock Exchange will commence on or around 11 May 2026.

On Admission, the Company will have 424,963,202 Ordinary Shares in issue, each with one voting right. There are no shares held in treasury. Therefore, the Company's total number of Ordinary Shares and voting rights will be 424,963,202 and this figure may be used by shareholders from Admission as the denominator for the calculations by which they will determine if they are required to notify their interest in, or a change to their interest in, the Company under the FCA's Disclosure Guidance and Transparency Rules.

Enquiries:

 

Cizzle Biotechnology Holdings plc

Via IFC Advisory

Allan Syms (Executive Chairman)

 

Allenby Capital Limited

+44(0) 20 3328 5656

John Depasquale (Corporate Finance)

Amrit Nahal (Sales and Corporate Broking)

 

IFC Advisory Limited

+44(0) 20 3934 6632

Tim Metcalfe

Florence Staton

 

About Cizzle Biotechnology

 

The CIZ1B biomarker is a naturally occurring variant of the cell nuclear protein CIZ1, which is linked with the preservation of epigenetic integrity. CIZ1B is highly associated with the presence of early-stage lung cancer and can be measured in small quantities of blood. The Company has developed CIZ1B into a non-invasive, cost-effective blood test to help in the early detection of lung cancer and has now entered commercial royalty-bearing arrangements to license its proprietary technology, and into collaborations with centres of excellence in cancer care. Cizzle was admitted to the Standard segment of the main market of the London Stock Exchange in May 2021. 

 

For more information, please see https://cizzlebiotechnology.com

 

You can also follow the Company through its twitter account @CizzlePlc and on LinkedIn.

 

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Date   Source Headline
21st May 20267:51 amRNSNotice of AGM
7th May 20267:00 amRNSIssue of Options, Salary Waivers, Incentive Plan
6th May 20267:00 amRNSConversion of Convertible Loan Notes
30th Apr 20267:00 amRNSFinal results for the year ended 31 December 2025
2nd Apr 20267:00 amRNS£250,000 Funding Facility
23rd Feb 20267:00 amRNSProgress on Launch of Biomarker Test in USA
4th Feb 20267:00 amRNSPatent Granted in Canada
5th Nov 20257:01 amRNS£250,000 Convertible Loan Note Issue
5th Nov 20257:00 amRNSLOI with leading UK Clinical Diagnostic Group
27th Oct 202511:32 amRNSChange of Registered Office
30th Sep 20257:00 amRNSInterim Results
29th Sep 20257:00 amRNSUpdate on Clinical Laboratory Partnerships in USA
18th Aug 20257:00 amRNSCommercial Progress in USA
30th Jun 20251:45 pmRNSResult of AGM
6th Jun 202511:00 amRNSNotice of AGM
28th May 20257:00 amRNSHolding(s) in Company
20th May 20257:00 amRNS£150,000 Convertible Loan Note Issue
30th Apr 202511:18 amRNSFinal results for the year ended 31 December 2024
28th Apr 20257:00 amRNSContract in Caribbean and Update on CIZ1B
14th Apr 202510:00 amRNS-RLaunch of New Website
25th Mar 20257:00 amRNSAppointment of Non-Executive Director
24th Mar 20257:00 amRNSUpdate on Launch of CIZ1B Biomarker Assay
2nd Jan 20257:00 amRNSAppointment of Professor Dawn Coverley as CSO
16th Dec 20247:00 amRNSUpdate on Strategic Partnership in North America
21st Oct 20247:00 amRNSExecution of Agreement for North America
3rd Oct 20241:12 pmRNSUpdate on Licensing and Partnership Agreement
30th Sep 20247:00 amRNSInterim Results
16th Sep 20247:00 amRNSHolding(s) in Company
9th Sep 20247:00 amRNSCollaboration with Moffitt Cancer Center
25th Jul 20247:00 amRNSUpdate on Strategic Partnership in North America
18th Jul 20247:00 amRNSManufacturing Agreement with BBI Solutions
9th Jul 20247:00 amRNSIssue of Share Options in Lieu of Consultancy Fees
24th Jun 202412:42 pmRNSResult of AGM
17th Jun 20247:00 amRNSUpdate on North American Strategic Licensing MoU
3rd Jun 20247:00 amRNSNotice of Annual General Meeting
13th May 20247:00 amRNSHolding(s) in Company
30th Apr 20245:00 pmRNSTotal Voting Rights
30th Apr 20249:12 amRNSFinal results for the year ended 31 December 2023
23rd Apr 202411:20 amRNSHolding(s) in Company
2nd Apr 20247:00 amRNSLicensing and Partnership MoU for North America
26th Mar 20247:00 amRNSPlacing to raise £0.62 million
28th Sep 20237:00 amRNSInterim Results
21st Sep 20237:00 amRNSUpdate on Put Option with Conduit
19th Sep 20237:00 amRNSCompletion of Evaluation Programme with Bio-Techne
8th Sep 20237:03 amRNSExtension of and update on Put Option with Conduit
15th Aug 20237:00 amRNSUpdate on Put Option with Conduit
10th Aug 20237:00 amRNSExpansion of Research Agreement and CIZ1B Update
30th Jun 20235:00 pmRNSTotal Voting Rights
28th Jun 202312:01 pmRNSResult of AGM
12th Jun 20232:15 pmRNSTotal Voting Rights

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