Baillie Gifford Commentary19 Oct 2022 13:43
I found these comments on the BG website for their International Smaller Companies Fund, AGL only takes up a small holding in what is a very diversified portfolio full of companies, of which many will be duds, so difficult to tell their conviction in the investment but still interesting IMO:
Angle is a UK based biotechnology company that has pioneered a system for extracting cancer cells from blood samples for testing. This year the company achieved a breakthrough FDA approval for its 'Parsortix' product. This now opens the door for it to commercially launch a liquid biopsy solution into the massive global oncology market. We have taken an initial holding as part of a fundraising the group recently carried out to help expand its commercial reach following the FDA's decision.
Opportunity: Given the size of the global oncology market the opportunity here is clear. The
company believes that the breast cancer biopsy space alone, where it has now received its FDA clearance, is worth in excess of $2bn.
Edge: Liquid biopsy has a clear edge over physical in terms of repeatability, safety, and cost.
Relative to other liquid biopsy peers, Angle's focus on CTCs (circulating tumour cells) is a clear advantage.
Sustainability: Angle's technology has the potentially to revolutionise cancer identification and patient care.
Alignment: The founder is still leading the business after almost three decades.
Scalability: This is the main challenge faced by the company. Having proven its technology Angle will now need to spend significant time and money driving commercialisation.
Insight: We believe that if Angle can execute on this opportunity then it should grow to many
multiples of its current size. We believe that being a small, illiquid UK business means this will stay under the radar of investors focussed on the larger US peer-group.