RE: Be plenty looking for some of those new patents10 Jul 2025 12:26
5. In-vitro screening for SERT, DAT, and NET release - Evotec appointed by Awakn to lead key preclinical testing.
To ensure the highest standard of preclinical validation, Awakn has appointed Evotec, a globally recognised leader in drug discovery and development, to conduct in-vitro screening for SERT, DAT, and NET release activity.
Evotec brings world-class expertise in:
Β· Neurotransmitter pharmacology
Β· High-throughput screening
Β· Precision drug discovery
Evotec's analysis will provide critical insights into the candidates' ability to modulate neurotransmitter release, a key mechanism underpinning AWKN-SDN-14's therapeutic potential.
This in-vitro testing phase, which builds on the positive animal testing results, is expected to be completed by the end of July 2025, aligning with the revised Programme timeline.
6. Preclinical animal testing.
Awakn has previously announced successful preclinical animal testing results for one of the three synthesised candidates. The study demonstrated promising early signs of efficacy, supporting the potential of AWKN-SDN-14 as a next-generation PTSD treatment. These results provide a strong scientific foundation for the next phase of testing.