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OPEN ORPHAN PLC's investor presentation on 9th Aug 2021 at 5:30pm
Seres Therapeutics Topline Results for SER-287 Phase 2b Study in Mild-to-Moderate Ulcerative Colitis
Primary endpoint of clinical remission compared to placebo was not achieved
Both dosing regimens of SER-287 were generally well tolerated
Open label and maintenance portions of the SER-287 study will be closed
I hadn't actually considered that the start date may have been the clients request, rather than the first available date.
However, the thrust of message for me is that despite having almost trebled our capacity in the last 6 months, we are continuing to expand the clinical footprint.
I am confident Cathal wouldn't be expanding the clinical footprint without there being an indiation of considerable orders to fil the beds.
It will be interesting to see the size of conversion, and type. If a negative air pressure facility is built this obviously gives us far greater flexibility, and i assume those trials requiring a negative air pressure facility will also be a little more profitable.
Also within the RNS
"With the ONGOING EXPANSION (my capitals) of our clinical footprint we can now provide any pharmaceutical company, anywhere in the world, RAPID ACCESS (my capitals) to challenge study clinical trials to gather data on their product in a relatively short time period." .
As Orph's three current locations are largely booked up for the rest of the year, being able to provide rapid access must mean that additional capacity will be coming on line shortly. Albeit the definition of "rapid access" in this industry may be several months.
I seem to recall Cathal has previously muted a 100 bed hotel conversion...
Plenty of upside from here.
As Cathal has made it public knowledge that Invesco have been offered 30p+ for their shares, surely they cannot realistically sell them for any less than that. It would be difficult to justify to their investors. 30p should therefore set us a new base with any luck. It will be interesting to see at what level they come back on the sell.
I consider it quite likely that Cathal will apply a retrospective date for the dividend entitlement. He has always alluded to wanting the share price to grow gradually without excessive peaks and troughs.
It seems to me that encouraging investors to hold onto the shares for fear of missing out, is a better way to achieve that than setting a date in the future with the inevitable inrush and subsequent exit of traders, and the volatility which would surround that.
What are peoples thoughts as to the level of sales required before an RNS is released? Obviously if a huge contract is secured on a national or state level as we hope, the value will be RNS worthy. However, is there a risk that sales may proceed well, but for example on a large number of small contracts which are not deemed sufficient to RNS, and thus we get no real sight of the value until a trading update?
Obviously if the latter scenario were to play out, there may be a belief that sales are not progressing as well as they actually are.
Further, how long does a sales contract take to agree? I assume that selling the tests wont be the same as selling a loaf of bread, and bespoke terms may need to be agreed with each corporation etc. As such, given that Beckman are only starting to sell mid February, is it perhaps wise to not expect an RNS for at least a few weeks (say March at the earliest?), and avoid any panic on the absence of one in the near future.
I would appreciate the thoughts of anyone involved in this field.
I was only half listening, as it happened right at the start of the meeting. I had been expecting a long talk, so just had the stream on in the background. However, the presenting officer said that she had been contacted yesterday by (i think) national government, and therefore was to be postponed for 21 days. I cant link as it was just the live stream of the council meeting.
Was deferred. looks like national government stepped in, so no consideration was given today to the application.