Member Info for TorquayFan

Inan's reply to yours WTP - in your link :-

"""We have developed (and patented) a new, cheaper and more effective PAP-based vaccine for the treatment of advanced prostate cancer which consists of a mutated 42mer PAP-derived peptide. The project will build upon the data generated to date by demonstrating the ability of vaccine-induced T-cells to slow-down/inhibit the growth of human prostate cancer cells and tumours expressing PAP. It will also assess whether CD4+ T-cells can be induced if a plasmid DNA coding for the entire PAP is first used, followed by administration of the mutated PAP 42mer vaccine. The project requires a highly motivated and dedicated student with the ability to deliver science of the highest quality and ambition to progress this new therapeutic towards a First in Man clinical trial"""

. . . . they are the same pap but "mutated" ... """CD4+ T-cells can be induced if a plasmid DNA coding for the entire PAP is first used""" That bit is Immunobody ....

Taiwan - 7 deaths - well done https://uk.yahoo.com/news/covid-19-one-taiwanese-scientist-104400418.html

Ray I think the 'trouble' was my fault this time but I was trying to help. BTW Inan could never return in another guise - somehow - he'd be spotted -(spelling, punctuation, sources LOL), but much missed. I think most would like him back. THEN I'll filter (sometimes) LOL

C7 within a minute you replied, so, I unfiltered. Read the posts - "I was tempted to 'unfilter' by your instant reply". It does bother you and your evidence would be welcome LOL. Filtered. Flitted. Faulted. Whatever. BFN

Hasiba - well done - should prove to be a good investment - any day or any year ! I jest.
The science will see us through OR is seeing us through ! ATB

As Inan and I and others, had some lively chats early in the pandemic on this topic - the 'herd' bit ain't going well, (or much else anywhere). Sweden already has up to 10 times the deaths of it's neighbours in Scandinavia and . . . we weren't to know, but it's sad. Https://www.dailymail.co.uk/news/article-9025989/Swedens-Covid-infection-rate-soars-Britain-Germany-Spain.html

C7 - I was tempted to 'unfilter' by your instant reply on this very quiet BB. Why did you say that ? I filtered the Inan 'quicksands' but read all new Inan topics. Do you have any evidence for your knee-jerk insult ? I'll answer on your behalf - NO. Your apology or evidence would be welcome . . . .

Coming back to yours earlier Ruck. Being me, I didn't realise that you were just baiting re. Inan, as you like to do. I guess you had a bad pain morning. If you remember, when Ray joined here trying to suss the science, Inan was great in helping him quietly. It's about the getting the best out of People, not driving 'em down. Of course I knew some would see Inan's reply there, but not most, so I posted it. Your slip is showing !

I can fight Inan as well as anyone - but I'll hear him too. I think maybe you should avoid the quicksand (or do you enjoy it ?).

Yes Ruck that's Inan's reply to 12.28, indeed it is. Interestng though . . . .

Noticed this over there - looks interesting, though I can't find where Inan's quote comes from . . . . . .

" "What makes this such a difficult problem is that the immune system considers cancer to be "self", so you get the equivalent of a civil war with the vaccine elements battling against other components of the immune system. So, for the vaccine to win the battle, it must have some pretty high calibre soldiers. Those high calibre soldiers when used against a foreign invader such as Covid19 are more likely to be successful."

The difference is cancer knows the immune system, it's broken the enigma code it knows what the enemy is doing so is able to throw the immune system off the scent despite markers that identify cancer to the immune system. The vaccine is not battling the immune system. What scancell is doing is playing a game of Activation over and above what a natural response would be . "high Avidity" - that is what most investors have still to understand ..... The Covid vaccine I believe will give you the second point of reference (scib1 1st) as to just how powerful a response it can deliver. "

It's a shame Inan is banned IMO

Barb - does it matter ? Just reply to the content ? Now you perpetuate ?
Doubts - you too ?

Hi Ruck - I remember Mabel. Smiler too, but, as with AimBig, I don't remember particularly where they were coming from, posting wise, but what's it matter ? I agree with your comment to Chester and AB has the right to put the record straight.

'Retrobates' - very funny. ATB

Ivy yes - a screen scorcher over there yesterday. AB I think this new thread could be fun. I was trying to remember others who inhabited these shores in early days and got as far as Puritas, Inanaco (whatever happened to him?), Boxa, Boomorbust (whatever happened to him too !), ONW. Loz and Tosh of course, but then my mind went blank - I'm sure more could be recalled. ATB

I remember Aimbig many years ago, but not where he fitted then, into any perceived hierarchy of position and merit. Myself I saw no connection to AB124 who posts well IMHO. Connection ? 1st two letters of the alphabet ? Whatever.

To liven things up here we need the ilk of a 'Loggie' or a 'Goy' or 'Super' etc. - a screen-scorching day over there LOL.

Concluding this extract, disturbing words - "exposure to misinformation reduced the proportion of those definite responses ((to vaccine take up)) by more than 6%" :-

" . . . false claims are that RNA-based vaccines like BNT162b can alter a recipient’s DNA and that the shots will contain tissue from aborted foetuses. While some of these are frankly comical, the fear is that the spread of misinformation into mainstream media sources could result in fewer people taking up the opportunity to be vaccinated, undermining the programme. Research published by the Vaccine Confidence Project – a unit of the London School of Hygiene & Tropical Medicine – found that misinformation around a COVID-19 vaccine induced a fall in the willingness to receive it among those who would otherwise “definitely” vaccinate. VCP’s study found that only 54% of UK people would definitely have a COVID-19 vaccine – higher than the 41% seen in the US – with most of those who were reluctant citing safety concerns or a sense the threat posed by the pandemic had been overblown. That’s already fewer than is required for herd immunity – a level of protection that would impact on virus transmission – but most worrying was that exposure to misinformation reduced the proportion of those definite responses by more than 6%"

https://pharmaphorum.com/news/social-media-erupts-as-anti-vaxxers-respond-to-covid-19-vaccine-approval/?

It's gonna be 'a long and winding road' is it not ? Thanks for that Dragon - here's more https://seekingalpha.com/news/3641506-supply-chain-issues-to-restrict-pfizer-covidminus-19-shipments-this-month?

Ruck - BioNTech's is the only vaccine atm so give it 'wellie' I say. I wonder when we'll hear about approval for 'Moderna' ? I guess Oxford / AZ is further back down the line now.

Ruck - storing at 2-8C in a fridge is easy enough - dosing Folks within say 4 days of exiting a -75C facility requires some drive and organisation. Good luck anyway . . .

The 'roll out' announcement - worth a few minutes or more https://youtu.be/gbXo25h4ro8

02.19 extracts taken from this full script . .
"Who will get it first and why? The Joint Committee on Vaccination and Immunisation (JCVI) initially said care home residents and staff should be first in line for the shots, followed by those aged over 80 and general health workers. However the Pfizer/BioNtech jab must be shipped in dry ice at -103F (-75C) and only lasts for five days once stored in a fridge at usual temperatures of 35.6F – 46.4 (2-8C) so it is impractical to roll it out in care homes. While the Government is insisting care homes will be targeted first, practically, that is unlikely to happen.

On December 2, Boris Johnson expanded more on how the vaccine would be implemented across care homes. He said: “Of course we want to get it into care homes as fast as we possibly can”. Though they are waiting to hear more, they are adamant that they will get it to “the most vulnerable”. However, in the response criticism that the temperature of the vaccine would make it difficult to be issued around care homes, Professor Van-Tam argued that it was “extremely unfair when one considers a new virus emerged less than 12 months ago and we now have our first vaccine”. Instead, it is expected only NHS staff will get the jab initially, and care homes may need to wait until the Oxford or Moderna vaccine is available before vaccinating residents and staff, as both can be stored at normal fridge temperatures.

NHS staff were told to get their winter flu jab by the end of November because there needs to be at least a week between the two vaccinations and NHS clinics have also been told to prepare for vaccinating their staff. Senior NHS officials claim the jab can only be transported once more after it arrives at a central hub, and has to be moved in batches of 975 – meaning the vaccine will be wasted if it is sent to smaller care homes which have only a few dozen residents.

However Pfizer has said the jab can be sent to care homes, as long as the vaccine travels for no more than six hours after it leaves cold storage and is then put in a normal fridge at 2C to 8C. So expect arguments in the coming days over who gets the first doses. At Wednesday evening’s press conference Sir Simon Stevens, the chief executive of the NHS, said care-home residents coming into hospital for outpatient appointments will still be able to access the jab."
https://www.telegraph.co.uk/news/2020/12/02/uk-approves-pfizer-coronavirus-vaccine-will-get-first/