RE: Test and release suppliers15 Dec 2020 19:53
Do we know how many thermal cyclers YGEN have? It would be interesting to know what their limiting factor for further scale up (ie, >20K) actually is? Acquiring additional machines may in itself have been a challenge, demand has been enormous with the Govt sequestered many machines.
IMO 20k/month isn't a huge number of tests and I have to admit I was quite alarmed when they made the announcement that this was their target as I had assumed that they were 'bigger 'than this.
My quick calculation, that equates to ~52 plates, I don't know how long the cycle run time of the C19 amplification is, but assuming it is between 30-90min then over a 24hr period a single PCR machine with accompanying automation could theoretically run about 16 plates. Over a month that would equate to ~480 plates (= ~185K tests/month). Obviously this would involve a single machine working flat out 7days/week and we all know in reality its doesn't (and clearly isnt) working like that because there is the human factor (head count, working hours etc) involved and nobody will be working like this (unless of course they are in Chinese testing lab). However the point I am making is that with more machines the burden on machine and man is less but the big numbers can still be met. So I wonder what is the testing infrastructure at YGEN and what has held them back?