RE: Cohort 418 Jan 2023 15:28
Copied this from David Chan MD:
In cancer clinical trials, if a study drug proves to be effective, patients who are benefiting are permitted to continue that drug even after the trial is completed.
I had a patient who was having a great response on a trial that turned out to be negative. The study drug was no better than standard treatment.
Yet, for that individual patient, the study drug effectively controlled her cancer and the pharmaceutical company allowed her to continue that medication for over 4 years even after the research was stopped and the experiment drug was shelved. Eventually it stopped working and I switched her to standard treatment.