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Mr Big
I am not anti vaccine as I know SNG001 has a role as a anti viral long term. I agree if that article is correct, the MHRA should be challenged on their decision. The issue is there is no voice to challenge, all UK Press are brainwashed and scared if they do speak out that they will be branded antixax !

I was asked today “ how did the MHRA manage to approve the vaccine so quickly”. My answer “when you have so little data to review, you either green light it or ask for more data” normal work you would demand more data !

Pregnancy impact
Elderly impact
High risk impact
Impact on drugs being taken long term
Impact on other illness
Impact on children
Does it stop you carrying the virus
What are the long term implications on the bodies immunity

It will be interesting to read what the MHRA based their decision on.
Oh and I am not any vaccines !

“I’m break even at the moment, it’s the future I’m concerned about” if that statement is true ... why don’t you sell at no loss and free up your day for negativity and spamming this board ?

Very strange behaviour. We do attract some virus.... just as well we have the worlds best anti viral drug to hand.

Mr Big demoted to Mr Small.

Mr Big never dreamed you were a troll.... no bridge would be tall enough.

1. I asked RM if he would confirm which company was involved. He said he would look into it. The company had asked to remain off radar. RM confirmed he understood why we would like to know.

2. Agree

3. We are working with very complex regulatory bodies across 20 countries. Anyone who has dealt with the FDA know how tough they can be. We are preparing both equipment and drug for approval. There is different languages and many many protocols to write and get approved. This process would normally take 1 year minimum to set up. Foresight is a valid challenge. If I had it I would have sold my shares at 250p and bought back at 83p !

4. Disaster no. They have over 40 recruits. This is a new challenging way of testing. If successful it will be revolutionary. The disappointment for me has been lack of awareness.

5. How anyone can say we “don’t have much to show for it” in the greatest of respect , I truly don’t think you understand what we have achieved to date, the amount of work that has gone into sourcing approving and validation of drug supplier and equipment suppliers. Everything you change needs approval. The company have delivered an outstanding and very uncharacteristic amount of work in such a short period of time. The regulatory bodies who approve everything Synairgen are doing are potentially the ones holding Synairgen up as they are not used to that speed of work.

6. I believe RM can and will take it to market. That is why I am here spending my time defending the company form some real trash being posted about them. (I’m not talking about you post)

Ultimately no should be pre-selling SNG001 until it is approved, however as RM mentioned himself, the company will have an opportunity to participate in Gov tenders once the drug is approved. And if the drug is as good as investors here think those orders will be from all parts of our beautiful globe.

I like the challenges and posts which are perceived to be negative. As mostly it’s the poster that hasn’t worked in the sector and realise quite how challenging it is.

Regulatory bodies take their time. We are nimble and quick and cutting through the red tape as fast as wrk can.

Let’s address the trolls face on:

1. Synairgen has appointed a 3rd party to negotiate the partnership/ licensing/ potential take over. This 3rd party is an expert in this field.

2. How safe is SNG001- if you need to ask this question you shouldn’t be investing. The company has been on th journey for 15 years. They have significant data on safety including 3 phase 2 trials. There is also independent data which shows safety of drug.

3. The Phase 3 trial is not delayed. The company confirmed Q4. The set up of a 20 country trial would normally take over a year. The team at Synairgen will deliver this in under 2 months. Also as I said earlier, the set up is as important as the trial itself. If Synairgen are going for BLA in America after the Phase3, they need to be 100% sure the FDA are happy the protocols in place will meet their requirements.
This is around the trial and equipment used.

4. I agree the Home Trials could be marketed better. I have emailed my thoughts to the business. I have even offered to leaflet drop my village, if the company provide a suitable PDF leaflet.

5. Ultimately I am shocked at how negative some posts have been. I guess if you are a trader you will be upset at the significant drop in price. However that loss is a paper loss only, similar to the 75p to 32p drop earlier this year.
As Richard has said many times. This share is about the End Game. If you can’t wait 6 months for what has the potential to be a life changing return, you maybe should be invested in Synairgen.

6. Valuation seems to be a dirty word here. I believe a Anti Viral drug like Synairgen will be worth £2 billion plus once approved. I know this number seems CRAZY and I will be shot down. Before you do that, maybe look at some historic sales !!!

In summary, the team are best in class and delivering a global Phase3 trial. We are desperate for it to start, no one more than the poor Covid19 sufferers in hospital. However the trial needs to continue to be best in class to ensure the approval process is expedited at the end. This is the final step to drug approval, it needs to be perfect and meet every regulatory requirement across all countries.

Very very exciting weeks ahead !!!

Morning
The set up of a phase 3 trial is as important as the trial itself. If the trial runs to the strictly approved protocol and and data collection and results are inline with pre agreed objectives, then it will expedite the approval.
The company are finding this with the FDA in America as well. They want to ensure the company have all the data and equipment tests in place, so when it comes to the end of the trial (on positive results) they can expedite the approval.

One interesting take from last night, was that Synairgen were revisiting their Phase2 data looking at long Covid.

The other interesting take was the use of words to describe SNG001. The world are noticing we have a “Broad Spectrum Anti Viral Drug” in the making and scientists are getting excited!

The other interesting take was our formulation is the most powerful out of all interferons and has minimal side effects.

This is heading towards the SuperDrug category.

All we need is good results, patience and patients !!

Anyone that has backed Synairgen from the start of the Covid19 journey will have already experienced the 70p to 32p price reduction earlier this year. The share price then bounced to a 259p high.
The company is now building a reputable Phase 3 trial in 20 countries. That is a bloody challenging thing to do for a major pharmaceutical let alone little Synairgen.

However the team are working non stop to deliver what should take 6 months in 1 month. They are focussing rightly outside of the UK. The FDA is a pig at best to get clearance from. If Synairgen achieves this, it will be the best goal so far.

I trust the team are doing their best to deliver value to us longer term holders. Anyone trying to trade should go back to you mining stocks. For most this is a journey which might end next year with a multi billion $ business.

For me crack on Synairgen, I can wait longer than a few months for that kind of reward.

The drug will potentially block anti viral effectors thus making you more at risk of viral infection.
This potentially increases the risk of covid19. However as it is Government sponsored it gets headlines with no challenges from the useless press.

If you have time please like and share the Home Trial Facebook page. Please ask your friends and Family to follow it as well. Let’s do our bit to raise awareness.
Might be worth posting the link throughout the day.

https://m.facebook.com/covidtrialathome/

NIHR have flagged SNG001 as an Urgent Public Health Phase 3 trial. This will prioritise SNG001 ahead of other treatments in the UK.

Synairgen are also collaborating with other trials in the UK and around the world.

Home trial is sitting around 50. They are recruiting 1-2 people a day.

Rather than bashing the company and individuals in it. Maybe spend that effort asking your MP why the UKGOV is failing to support Synairgen. Maybe if they have allowed the drug onto the Recovery trial, we would be in a much better place.

Anyone who is invested here will know that the American Home trials will highly likely be funded through US Government.

People should maybe look in the mirror before criticising. Anyone who thinks they could do better, maybe shouldn’t be wasting their day on here, I bet you have a Pharma business to build.

This company has moved the earth in terms of progress. Well don Synairgen well done Richard Marsden.

It’s clear those who are invested and those subtle deramping. Anyone doubting Richard Marsden’s drive, commitment and passion should maybe leave the board.
This company has achieved more in the last 8 months than most achieve in a lifetime.

The team have dedicated 15 years to this drug already. In the last 6 months they are making SNG001 a global name. The real mega news has yet to come. Let’s get the Phase 3 trials announced early December and then we will know exactly what the team has been working on so ahead to deliver.

As most know, I haven’t posted for a while. I have watched and read some real crap being written here.

It would appear than som are happy to spam the board so all decent posts are quickly lost. It would also appear that the subtle derampers are happy to pick up negatives rather than trying to fix them.

Yes the company only had 30 on the trial back on the 19th. Recruitment has been tough without Lancet publication and Government backing. Why do you think we are looking to extend the trial into America ??? At least that Government supports this business.

Matt Han**** could easily have helped raise the profile of the Home Trials. He has failed and only focused on his mates in Oxford. Synairgen are doing the right thing and moving the trials to where they will gain support at all levels of Government.

The current share price does make Synairgen open to a bid from a major pharmaceutical. Most would have laughed at a £3 bid a few weeks ago, however I am sure allot on here would be happy with that today.

Personally I hope we Remain independently run for as long as possible. The value is in the data we gather and multi platform drug we are developing will be worth allot more than £3 per share.

The issue with AIM traders is they mostly want a return tomorrow. Synairgen will return next year. That is to long for some.

For me I have been invested from March. I have seen the share go from 6p to 70p to 32p to 229p and now we are at 87p. I personally believe the company will be worth a minimum £2billion next year.... if everything goes to plan. That is roughly in line with one brokers valuation.

I can’t see me getting that kind of return in any other investment. So I will hold and when possible buy at this level. It is the End Game that counts.

Oh and yes I hope anyone shorting or playing with this share burns. This company is working non stop and deserves the support of shareholders and Governments!

Unlike the UK, the US Government are being extremely supportive. If there is an opportunity to run a home trial across the USA this will be supported fully at State and National level IMO.

Yes the USA Home Trial news is significant.
I messaged the company on this today. I think the Prof wasn’t supposed to mention it. He is a ultra intelligent man but not as commercial as RM might like.

The USA is a major break through for Synairgen. The FDA are working closely with the business to ensure we meet their strict requirements.

Very exciting

Anyone doubting news flow over December shouldn’t!

We will have multiple announcements due.
I have also asked the company to confirm who is handling the partnership/ licensing discussions.

I would personally struggle to sleep if I was short on Synairgen. Companies like this / investment opportunities like this don’t come around that often.

https://www.covidtrialathome.com/

I have just read that some people Were trying to short SNG.
That seriously can’t be true, or they simply don’t understand SNG001 and what is happening behind closed doors.

Everyone should also recognise the amazing team at Synairgen. They have best in world experience and will know people across all critical areas:

Stephen Holgate co founder
Dr Bruce Campbell over 40 years Drug development experience
Loan Buchanan 40 years pharmaceuticals experience at CEO level.
Dr Philip Monk years at Bayer then onto Cambridge Antibody Technology.

This team and the extended team of employees and consultants are simply ground breaking.