Stephan Bernstein, CEO of GreenRoc, details the PFS results for the new graphite processing plant. Watch the video here.
My feeling is this will work but the question remains as to the scope - panacea or targeted and if the latter (likely?) how much so. Either way this must surely be met with rewards, it is just a case of how big. By rewards I mean for society primarily and for us secondarily (without the former the latter will be diminished).
This is still interesting - the discovery of an IFN stimulated short ACE2 receptor. I like this 'behind the paper' article - they say they discovered this on a budget of £10K. Clearly early days again in understanding the amazing ways we have evolved to this type of viral infection - as long as we can side-step the viruses counter attack on suppressing IFN... hmm. Fingers crossed on results.
https://microbiologycommunity.nature.com/posts/discovering-a-new-ace2-isoform-rallying-to-understand-sars-cov-2-infection
Okay 5x, 6x whatever, not 500 times. The 500 number is based on something I have not yet read about in terms of spike/ACE-01 affinity and how that translates to infectivity and how they arrive at these numbers.
500% more infectious is 5x, not 500x, more infectious I think. Otherwise I would be rich. LTH here and scientist. We need to observe mortality rates with this one which will become clear in the next months. This becomes less about the virus but the resilience of society which is what keeps me awake at night.
Hear Hear Doc.
Hi All,
I had a look at the old paper that has been posted today and I think precipitated some of the arguments on the board. I also looked at the paper this one cites around the interferons used. The authors say they were using unknown mixtures as they could not properly assess the relative abundance of proteins present. They saw efficacy against coronavirus but poor side effects after administering for a few weeks I think. So a very early study and with unknown mixtures and goodness knows what excipients were present. The SYN formulation is pure interferon 1b, free of excipients and a world apart from this work as all science builds and hopefully gets better. No such safety concerns have been reported with current studies so this puts into context just how important the current formulation is. But I read the paper as wow, they saw efficacy even with the mixture of ?? they were using back then.
Thank-you Joey!
Still here and sign me up....
Ditto Skeletor, got some at 163p
Marvellous news, the story is unfolding nicely and reward for LTHs. GLA.
Great Ducati2 - many thanks for the link.
... and a rather unfortunate logo given the share price.
Very interesting that MRC is choosing to release this now. UKRI who distributes funding to all of our research councils are always desperate to demonstrate impact. This certainly would provide that and perhaps there is growing confidence behind the scenes.
Absolutely TLW, still sitting tight here and enjoy posts during coffee breaks. I have not been tracking the IFN literature so much now as I feel the only experiment of any worth now is the one we are all waiting for and the answer to the enigma of when best to give IFN, to whom, and probably as important as avoiding mortality, will it help ameliorate long term effects?
Yep Woodstock, and schools back in England next week followed by HE in late September. Time to don the Hazmat suit and do a welcome week lecture to 200 students.
Ft article for those with a subscription - Israel is the vanguard for vaccines and need for third booster shots and why I am still hanging strong for treatments.
https://www.ft.com/content/c21e2053-0373-4b8e-80b7-fad10f235604?fbclid=IwAR1qWqVsi-Sk221PhWczaHeq_W07BpTC6xZBb1gERKFZ4jUJv1ksLBi9MNc
Hey Woodstock, what has spooked you? I share the same troubled nagging feeling in the back of my head but I am a scientist and woefully poor at assessing market tides.
Yep, just google Reade Eugene Griffith to get an idea of this outfit.
Yes thank-you SB for taking the time to put all of that together. You only have to walk around to sense everyone thinks this is over and it is unnerving that the sheep just follow the whistles from the chumps in charge. Keep exercising caution, wash hands, wear a mask and stay clear of people - you will thank yourself in a few years time. My wife and I have already been branded with the 'Oh you are being careful aren't you' brush when we didn't attend a large family gathering. Until I am convinced otherwise I am sticking with the cautious line!
Derek Lowe is a respected source and has been doing this a long time and not just in this area. I would say his blog will give you lots of ideas and in different areas as well.