Member Info for Rahulrajas

Thanks for the link. It states
“If SNG001 proves to be beneficial it would be a major breakthrough for the treatment of COVID-19.”
Hopefully trial results in next couple of weeks.
GLA

Imagine the sales in every Flu season.

Agree - LP. This is exactly what I’m saying. Pointless discussion over very minute details and losing the sight of the overall bigger picture.

Onwards and upwards.
GLA

Because the nervous traders are out who researched and discussed ACE2 in detail over the weekend.

iamrich - we don't know about any effective drugs. The whole world is waiting for for a drug that works.
However, we know the drugs that don't work
1) Remdesivir - leaked WHO paper
2) Hydroxychloroquine - as this has been stopped by some countries, i think Sweden, due to cardiotoxicity

Very likely we’ll get a RNS tomorrow.

4) The trial has been fast tracked.

Agree Oranges . A lot of poster here are tying to micro-dissect things they don't understand.
Remember
1) we are getting closer to the trial being completed.
2) We all know interferon is helpful in fighting viral infections.
3) There is a reason why interferon beta 1a is in the WHO solidarity trial.

COVID19 inhibits the rapid expression of interferon type 1 (IFN-1) [2]. IFN-1 is known as the “initial alarm” upon encounter with the virus that modulates the immune cells to the so-called “antiviral state”.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175888/

This is a double blinded controlled trial. That means nobody knows if they are receiving SNG or placebo

The trial has 100 patients from 10 sites. So 10 from each site.

Yes, that’s sad. There are many patients on trial and only 10 in SNG trial. Out of the 10 probably 5 would receive placebo.

Hardtohandle - this means the price will go up now.

That’s why we are stalled at this price.

Peter - good find.
Confirms that SNG would work wonders.

GLA

Global stocks fell after a potential antiviral drug to treat coronavirus flopped in its first clinical trial, dashing investors’ hopes for a quick medical solution to the pandemic.
FROM FT

Among these IFNs, IFN- beta was already found to strongly inhibit the replication of other corona viruses, such as SARS-CoV, in cell culture, while IFN-alpha and gamma were shown to be less effective in this context [211]. There are evidences that patients with higher susceptibility to develop Acute respiratory distress syndrome (ARDS) show indeed deficiency of IFN- beta.
https://greenelab.github.io/covid19-review/

Among these IFNs, IFN- ?? was already found to strongly inhibit the replication of other corona viruses, such as SARS-CoV, in cell culture, while IFN-?? and ?? were shown to be less effective in this context [211]. There are evidences that patients with higher susceptibility to develop Acute respiratory distress syndrome (ARDS) show indeed deficiency of IFN- ??.
https://greenelab.github.io/covid19-review/

Hopefully Manchester recruitment is complete as well.
https://twitter.com/MFT_Research/status/1253290753373110277