Member Info for Oultonmike

.74 to sell ajbell

Just the beginning. This should give us confidence that management can get the sales across the line.
Many more to come.
Goodbye 2p
Gla

Incyte and Eli Lilly may have JAK inhibitor mechanistic edge over Pfizer for COVID-19 while Theravance may be limited by nebulised approachInterest in a class of drugs called JAK inhibitors to manage COVID-19 is building, and with three such therapies already approved for other diseases, the race to repurpose these treatments has kicked off. Incyte’s Jakafi and Eli Lilly’s Olumiant may have mechanism edge over Pfizer’s Xeljanz, according to reporting by Reynald Castañeda, Pharma Writer for the Investigative News team at GlobalData, a leading data and analytics company. Meanwhile, a fourth candidate – Theravance Biopharma’s TD-0903, which is not yet approved – is also in the fray and stands out for its inhaled mode of administration but its efficacy value is nebulous so far.

Castañeda comments: “JAK inhibitors have grabbed the world’s attention given clinical experience showing that the hyperinflammatory process called cytokine storm syndrome, commonly seen in COVID-19 patients, is a turning point in disease severity. Interviewed experts noted that JAK 1/2 inhibitors such as Jakafi and Olumiant may have a clearer link to downregulating interleukin (IL)-6 to ease the cytokine storm compared to JAK 1/3 inhibitors like Xeljanz.”

Pfizer in the market for our JAK?

Tweet from last week obviously comparing compounds. "In the first quarter, Jakafi posted global revenues of $459 million, Incyte said."
Sareum MC £23m
Something is brewing imo

Great information ajithoth.

4.WO/2020/074461TYK2 KINASE INHIBITORS

WO - 16.04.2020

Int.Class C07D 263/48Appl.No PCT/EP2019/077118Applicant SAREUM LIMITEDInventor READER, John Charles

The invention provides compounds of the formula (1): (1) or a salt or tautomer thereof; wherein R1 is hydrogen or fluorine, pharmaceutical compositions containing the compounds and medical uses of the compounds (for example, in the treatment of inflammatory or immune disorders).

Quite recently dated! Been tinkering with the TYK

Also Evaluate dated December 2019 bc (before covid)
Gla

It is frustrating but not long now. The tweets tell us the direction Tim is going.
Buying another £2k Monday.
Gla

investor110
Excellent information. Much appreciated.
Gla

The newest drugs for the treatment of rheumatoid arthritis are the Janus kinase (JAK) inhibitors.
Mighty big rns if everything is ready to align

Have I got this right? Funds raised since June 2019 £1,294,684 + £50,000 FLT3+ AURORA KINASES SAR-20293.
Should be plenty left in the kity. Wasn't spent on the Biotrinity presentation ;-)
Cheers

Marshall Ma, MD of Link China Pharma Solutions, said: “China’s healthcare spending is projected to grow from $357 billion in 2011 to $1 trillion in 2020, China will be the 2nd largest pharmaceutical market by 2020. Since 2006, 13 out of 20 top pharmaceutical multi-national companies have invested heavily and established R&D centres in China. It will be a great opportunity for both Sareum and HMUBEC to enter into this win-win deal arrangement to efficiently advance Sareum’s leading oncology programme into clinical trials and onward for possible marketing approval.”
366 Professors, senior researchers and physicians. 967 associate Professors!
How are they getting on?

Tomorrow again then. Yaaaawn....
Busy tweeting and putting the mega deal together. Fair enough

Just had a little top up. Only 100,000 but will be nice at the 5p
Gla

Andy
.9 becomes .88
I'm going for a lie down!

In layman's terms here's a tweet to get the sp moving for the day traders.

Sorry, only banter I'm bored tf
Gla

Sierra closed nearly 12% up. I couldn't find any news. Something brewing

Looks like we will finally push towards that £1.20 finncap valuation.
Gla

Fitted into the programme perfectly. Should be lots more interest tomorrow. In for a pound
Gla

They can buy SNG

Coronavirus: When Will We Be Safe?

Panorama

As politicians decide how and when to lift the lockdown, Justin Rowlatt reports from the scientific frontline, finding out how science can help us defeat the virus. With access to key drug and vaccine trials, he reveals a race against time to help save lives, and he asks when are we likely to be able to return to a normal life.

Maybe Tim's been interviewed! Lol

Looks like the next drop to 8p about to come round. Hope I'm wrong