Member Info for Oultonmike

Only 3,050 million to account for now!
Just 1 million for me. Hoping to add to it before the mega rns/buy out.
Hope I don't become a lth lol
Respect to all

How could I forget! Every day feels like a bank holiday.
Tuesday rns it is then.

Need to sit on your hands and not sell. Big buyer knows something surely.
I'm hoping no rns in the morning. Another nice steady tick up preferred.
Rns Monday better!
Gla

Hopefully a realization of farming out Timor leste!
That would be massive news.
Gla

Website Overview.
TYK2/JAK1 - Covid-19
Whilst developing SDC-1801, we have produced compelling cellular and in-vivodata in models of autoimmune disease to demonstrate the beneficial effects of SDC-1801 in modulating the key cytokines involved in the cytokine storm phase of Covid-19. Details can be made available to potential funding, collaboration and/or licensing partners on request.
Good positive updates to the site today. Might be to keep us interested.
BoilB. I like your 8p and wouldn't mind the wait. Don't think it will be tomorrow though.
Gla

Apologizes. In preparation.
Not submitted but surely must be a priority unless you have a deal in the background and don't want to tie yourself in.

Development.
SDC-1801 top of the list and I'm sure the arrow has moved closer to clinical phase 1.
GRANT APPLICATIONS IN PROGRESS
Rns incoming?
Also FLT3 shows as out licenced.
Gla

Does look held back.
Lse showing 1 mil at 13.01 sell! Not at that price if at that time.
Any week now.

Muscle weighs heavy!

From rns 10th September 2018
"We intend to focus our resources on advancing SDC-1801 through preclinical development and into clinical trials over the next 18 months. At the same time, we will continue our discussions with potential licence partners for this exciting drug candidate.”
Can't be long to commencing clinical phase one.
That would be MASSIVE in today's current situation.
Gla

Easier to read on the Red Emperor website.

1BARCLAYS DIRECT INVESTING NOMINEES LIMITED 43,076,5548.202INTERACTIVE INVESTOR SERVICES NOMINEES LIMITED 33,673,5796.413HARGREAVES LANSDOWN (NOMINEES) LIMITED 31,469,3495.994INTERACTIVE INVESTOR SERVICES NOMINEES LIMITED 30,557,0695.825MORGAN STANLEY CLIENT SECURITIES NOMINEES LIMITED25,000,0004.766SURF COAST CAPITAL PTY LTD 24,000,0004.577HSDL NOMINEES LIMITED23,500,5194.478HSDL NOMINEES LIMITED 17,865,6033.409JALAVER PTY LTD 16,900,0003.2210HARGREAVES LANSDOWN (NOMINEES) LIMITED 15,555,4842.9611HARGREAVES LANSDOWN (NOMINEES) LIMITED
14,566,4202.7712SHARE NOMINEES LTD11,463,6672.1813INTERACTIVE BROKERS LLC 10,501,0832.0014HSBC CLIENT HOLDINGS NOMINEE (UK) LIMITED 9,427,4341.7915LAWSHARE NOMINEES LIMITED 6,702,4001.2816J P MORGAN NOMINEES AUSTRALIA PTY LIMITED6,434,6511.2217LAWSHARE NOMINEES LIMITED 6,363,1621.2118WEALTH NOMINEES LIMITED 6,294,5571.2019JIM NOMINEES LIMITED 6,052,9961.1520INTERACTIVE INVESTOR SERVICES NOMINEES LIMITED 5,845,5791.11Total345,250,10665.73Total Remaining Holders Balance180,042,67034.27

As at 16 March 2020
Gla
 

RNS dated 27th March 2020
The Group's current cash and short-term deposits will meet the existing commitments and operating needs for at least a year. The directors anticipate that the Group will secure sufficient equity-based funding and/or revenue from partnering agreements during the coming year to ensure the continued advancement of the Group's programmes. Therefore these financial statements have been prepared on a going concern basis.
I'd like to have a tenner on an rns at 1000-1 please!
Patience still needed.
 

Phase I clinical trials of CHK1 inhibitor CCT245737 (Sareum Holdings Plc.) Monotherapy or combined with cisplatin and gemcitabine are recruiting subjects (NCT02797977 and NCT02797964).

The Company notes with interest a paper in the European Respiratory Journal published in 2017, suggesting that TYK2 inhibition might be effective in the treatment of influenza driven secondary bacterial pneumonia. While the Company is not aware of any ongoing studies in this space, this is potentially highly relevant against the backdrop of the Covid-19 pandemic. The Company intends to investigate grant funding opportunities to assess the potential use of its inhibitors to address this threat to global public health.

 The Group's current cash and short-term deposits will meet the existing commitments and operating needs for at least a year. The directors anticipate that the Group will secure sufficient equity-based funding and/or revenue from partnering agreements during the coming year to ensure the continued advancement of the Group's programmes. Therefore these financial statements have been prepared on a going concern basis.

Financially sound imo
Gla

 

Morning all.
Nice light hearted post RMM much needed thank you.
I noticed Motif Bio rns a tr1 and the sp rocketed! Hoping someone building a position here.
Unfortunately not me but I have added another 100k on the drop today. Getting closer to 3% lol
All the best Mike

I've been following this quite closely. Gives an idea as to the size of trial and doses needed.
Synairgen's Phase II trial in COVID-19 patients (SG016) will be a double-blind, placebo-controlled trial. Initially, the pilot phase of the study will involve 100 COVID-19 patients, will take place across a number of NHS trusts and has been adopted by the NIHR Respiratory Translational Research Collaboration  which is comprised of leading centres in respiratory medicine in the UK whose internationally recognised experts are working together to accelerate development and discovery for COVID-19. A successful outcome from the pilot phase will inform onwards progression of SNG001 in COVID-19 patients. 
Hopefully be able to change the above to Sareum JAK

June 2019 placing to progress proprietary TYK2/JAK1 programmes in preclinical development.
Nearly a year of your life!

Nice top up. Only 100k myself (I dont mean £).
Understandably quite a few nervous investors here.
It might be nice if Tim asked us to be patient. But would that need to be in an rns with details of a direction he is taking us?
Had it once with ncyt. Sales rns and asking for patience. That was one horrible bb!
Gl

I'm with you Roxbury.
No expert but confident. I had a little top up.
Patience needed.
Gla

Now that's a shake! Get the weak out before the news Tim has been building up to arrives.
In my dreams gla