RE: Approach22 Sep 2023 13:26
Dr Alastair Smith, Chief Executive of Avacta Group plc commented:
"I believe that we are on the verge of a paradigm shift in how chemotherapy is delivered to cancer patients.
The safety and initial efficacy signals emerging from the data in the AVA6000 Phase 1 study are very encouraging indeed. The pre|CISIONTM platform is doing exactly what it was designed to do - target the release of active chemotherapy to the tumour tissue, sparing healthy tissues and improving the safety and tolerability of the drug whilst delivering potentially superior efficacy.
I'm particularly pleased that, even at this early stage and in this patient group, we have a confirmed, significant response in a patient with soft tissue sarcoma, as well as other positive signals across a number of other patients.
We're now aiming to accelerate the clinical development of AVA6000 and begin the Phase 2 efficacy study earlier than originally planned. The Phase 2 trial will follow a short study to determine the safety and efficacy of fortnightly dosing to allow us to determine the recommended Phase 2 dosing regimen.
I look forward very much to sharing the detailed data from the Phase 1a study in due course."