Sirt627 May 2026 22:06
In step toward immortality, Israeli scientists say they can ‘rewind’ aging in mouse livers
SIRT6 ‘longevity’ protein reverses DNA structure in new peer-reviewed study by researchers at Bar-Ilan University and US National Institute on Aging; treatment seeks to extend healthy human lifespan
May 27, 2026
Researchers from Bar-Ilan University, the US National Institute on Aging, and Tel Aviv University say they have reversed key signs of age-related decline in the livers of older mice by boosting levels of SIRT6, known as the longevity protein.
The peer-reviewed findings, published in Nature Communications, suggest that biological changes associated with growing older might not be a one-way street, after all.
Using advanced tools to map out DNA architecture and measure real-time gene activity, the research team studied older mice that had been given additional SIRT6, which silences genes associated with inflammation and aging.
.............
Dr. Nir Barzalai, director of the Institute for Aging Research at the Albert Einstein College of Medicine in New York, and president of the Academy of Geroscience, told The Times of Israel that his own research focuses on how aging has “distinct biological drivers that can be targeted to prevent age-related diseases.”
Barzalai was not involved in Cohen’s study.
Barzalai, who has studied “hundreds of centenarians,” said he found a few of them with mutations in Sirt6, associated with slowing their aging.
“The discovery of Sirt6 in animals and humans shows [the possibility of improving] healthspan and longevity,” Barzalai said. “This is probably the most important discovery in human biology.”
He added that SIRT6 therapy is part of a new science that treats “our health, not our diseases.”
In step toward immortality, Israeli scientists say they can ‘rewind’ aging in mouse livers htTps://share.google/9GSCc2qsoKNoj7Dgv
Sign In
Follow the stocks
