Nutritionaloutlook - Heart smarts6 Jan 2023 17:14
recent article here (3rd January 2023) with Zak commenting
https://www.nutritionaloutlook.com/view/heart-smarts-nutrition-researchers-unveil-new-benefits-of-natural-ingredients
Research has found that in addition to their effects on cholesterol levels, probiotics can influence the risk of coronary heart disease. Zac Sniderman, director of business development, North America, OptiBiotix Health (UK), says a recent study6 on the branded OptiBiotix Lactobacillus plantarum ingredient LPLDL showed that the ingredient can reduce non-HDL cholesterol and apolipoprotein B. This study, a randomized, double-blind, placebo-controlled pilot trial funded by OptiBiotix, assessed the effects of the L. plantarum on cholesterol in 16 adults with high cholesterol. The subjects were randomly assigned to receive either 4 billion CFU of L. plantarum per day, or a placebo, for six weeks, followed by a three-week washout period. The study found that six weeks of L. plantarum consumption decreased total cholesterol by 34.6%, LDL cholesterol by 28.4%, non-HDL cholesterol by 17.6%, and apolipoprotein B by 28.6%.
“More recently, OptiBiotix has been investigating the effects of novel prebiotics, such as xylo-oligosaccharides (XOS), with our probiotic strain LPLDL,” Sniderman adds. “Our research has shown that when XOS is combined with certain probiotic strains, there is an increased rate of growth activity in the gut, accentuating the health benefits.”
there is also another US company using a different strain
Sid Shastri, director of research and business, probiotics division, at Kaneka Americas Holding Inc. (Pasadena, TX), says Kaneka began developing probiotics for heart health over 10 years ago. Kaneka’s internal studies have shown that Floradapt Cardio, the company’s patented heart health probiotic ingredient, can reduce LDL cholesterol and triglyceride levels. Floradapt Cardio is a blend of Kaneka’s proprietary Lactobacillus plantarum KABP-011, L. plantarum KABP-012, and L. plantarum KABP-013 strains. The blend contains 1.2 billion CFU per 100-mg capsule.
More recently, a 2021 randomized, double-blind, placebo-controlled trial5 examined the effects of Floradapt Cardio and red yeast rice extract (containing 10 mg of monacolin K) on LDL cholesterol and other biomarkers of blood lipid concentration in 39 subjects with high total cholesterol (200 mg/dL or more). Subjects were randomly assigned to receive either one capsule of Floradapt Cardio per day, or a matching placebo, for 12 weeks. The subjects were examined for body weight, BMI, body fat percentage, blood triglycerides, LDL cholesterol, and total cholesterol at baseline and after 6 and 12 weeks.
mind as we know the FDA have banned their use and the EU is considering same
https://www.nccih.nih.gov/health/red-yeast-rice
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