RE: BBC report20 Jan 2020 21:15
Nuvec silica have a unique irregular (spiky) surface structure, coupled with polyethyleneimine (PEI), that simply and effectively traps and protects nucleic acid (such as mRNA / pDNA) as it travels to the cells. Once inside the cell, the nucleic acid is released to activate the immune system. Nuvec is also a natural adjuvant so it attracts large numbers of antigen-presenting cells which, in turn, leads to a strong activation of T-cells, increasing the level of immune response against the target cancer cells.
Nuvec loading process in order to increase the consistency of the in vivo performance. Once successful, this will allow the company to move from exploratory collaborations to engage in full licensing discussion