RE: SP RISING FAST4 Mar 2021 13:52
The current gold standard for estimation of viral load continues to be laboratory-based PCR tests, but these detect viral RNA levels and not necessarily the presence of infectious virions, which means that many patients test positive long after they are no longer infectious.
The AIM-listed firm noted that Paraytec has thus adopted an additional comparator test developed by the University of Sheffield to verify the presence of intact virus particles.
This involves ultracentrifugation and high-resolution fluorescence microscopy to independently verify the presence of virions in clinical samples.
In parallel to the sample processing described above, the Paraytec team has been using isolated lab-grown virus to optimise the operational sensitivity of its instrument for the detection of pre-symptomatic and early-stage symptomatic virus levels.
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