NIHR - Covid Studies Comparison.18 Apr 2020 17:06
Have been familiarize myself with the wording on NIHR Covid studies, thought i'd share.
https://www.nihr.ac.uk/covid-studies/
Gilead Sciences
The primary objective of this study is to evaluate the efficacy of 2 remdesivir (RDV) regimens with respect to the normalization of temperature and oxygen saturation through Day 14 in participants with severe coronavirus disease (COVID-19).
Key takeaway - Evaluating efficacy (no prior understanding)
Gilead science in severe cases
The primary objective of this study is to evaluate the efficacy of 2 remdesivir (RDV) regimens with respect to the normalization of temperature and oxygen saturation through Day 14 in participants with severe coronavirus disease (COVID-19).
Key takeaway: Evaluate Efficacy
Chroroquine (Status noted as unavailable...)
There are preliminary reports emerging from China of clinical benefit in the treatment of COVID-19 infections (16), and increasing consensus that chloroquine should be evaluated urgently in the prevention and in the treatment of COVID19 infections. We hypothesise that chloroquine might slow viral replication in exposed subjects, attenuating or preventing the infection. Given the enormous experience of use in chemoprophylaxis, excellent safety and tolerability profile and its very low cost, if it proved effective then it would be a readily deployable and affordable preventive measure for high risk individuals such as health care workers.
Key takeaway - Hypothesis led.
Synairgen
The purpose of this study is to confirm that SNG001 can prevent/limit the worsening of LRT illness in the context of SARS-CoV-2. Safety and efficacy will be assessed.
Key Takeaway - Previous data has shown something, and this trial is to confirm those findings.
There are others that i have not yet read but guys, read between the lines here.
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