wrong Demon the reason SBs stop taking open position is for 3 reasons 1The market cap has gone below £10M 2 They have reached 3% of the issue in open position. 3 Broker has raised the Risk premiums.
Take out non core and ORPH will need to be generating £350 -£500 Million a year in revenue to justify a MKT Cap of £1 Billion. Pharma services companies valued at 2-3 times revenue. Using PE lets give ORPH a PE of 15 Profit of £60_70 MIllion a year needed to justify £1 Billion.