RE: RNS18 Dec 2025 07:04
Christina Coughlin MD, PhD, CEO of Avacta, commented:
"These data are key to support the clinical development of FAP-Exd (AVA6103) and the profile of this second pre|CISION medicine in the preclinical setting is tremendous. The sustained release mechanism developed by Avacta scientists results in a robust concentration of active drug in the tumor over five days with the disappearance from the bloodstream in only two hours. This is the exact profile needed to achieve better efficacy with this highly potent topo I inhibitor.
"Our AI collaboration has led to several key insights into the patient population for the FAP-Exd program and has helped to drive a smarter and faster clinical trial. We are eagerly anticipating the next steps for this exciting program in 2026."