Member Info for Iseenoships

Someone has took an interest in it, spent 100k just before the bell. It makes me more comfortable with my holdings when these big buys come in.

It's like asking a geologist where the best place to find gold is and going 50 50. He shows you the best place to look and you do all the digging. One day there's going to be big returns.
I do think Etx has something very valuable here and I was very impressed in the way Ali tried to explain how it all works
. I have a better if limited knowledge of this company assets now.

Yeah I've registered. I'm hoping we might get an rns before Wednesday close, there's plenty to update on and potentially big news.
Fingers crossed.

Ha did cross my mind but no one really looks at this board just us. I'm going to try and increase over next few weeks if possible. If just they pull this off, this will be in the ££s. Just on this alone.

Also...
We have uncovered new mechanisms that mitigate infection-induced hyperinflammation as well discovering a potent anti-viral strategy. Our findings have highlighted Bardoxolone Methyl which is already the subject of an investigator led COVID-19 trial (NCT04494646).

The surprise finding of this compound's anti-viral activity alongside its well observed anti-inflammatory properties has led us to file a patent (GB2017631.9) which describes the use of Bardoxolone and related compounds to treat Covid-19 and other viral diseases. Previous knowledge of similar compounds has focused on the activation of the NRF2 pathway. Here, we show that both the anti-viral and anti-inflammatory properties we have observed depend on GRP94. We demonstrate that other selective GRP94 inhibitors may also be active anti-virals against a range of coronaviruses. Should Bardoxolone Methyl be progressed from its Phase 2 safety evaluation in NCT04494646 into Phase 3, we would be happy to share our anti-viral analysis with the sponsor.

To date, no compounds with this type of potent dual activity have been reported and clinical approaches have focused on combination drug therapies using anti-inflammatory compounds such as dexamethasone combined with anti-virals such as Remdesivir. Irrespective of our findings for Bardoxolone, we believe that our project will open deeper interest in selective GRP94 inhibitors and GRP94 as a possible target for future development of therapeutics not only for COVID

Re reading the rns a couple of times today and I think this has been vastly overlooked, especially by investors like myself. Take another look and see what you think to this part of it.
In May 2020, small molecule compounds predicted by our platform were tested in validated SARS-CoV-2 in vitro assays at WuXi AppTech. These compounds showed potent anti-inflammatory and anti-viral activity. We report here that in vitro assays have confirmed our in silico predictions and we have identified a clear mechanism, target and clinical stage compounds. These compounds are active against GRP94 and have anti-inflammatory and anti-viral activity against Sars-CoV-2. This activity generalises to other alpha and beta coronaviruses and is expected to be generically applicable, raising the prospect of utility against both existing coronaviruses that cause serious disease such as SARS and MERS and against new emergent strains of coronavirus.

The clinical stage compounds identified have been developed in humans for alternative indications and have an established safety profile in man. These, and other selective compounds sharing this target, could be rapidly deployed into clinical trials to treat patients with serious Covid-19 disease. Given our mechanistic insights, it would also be feasible to develop novel, highly selective drugs against GRP94. We continue to work on repurposable combinations using our platform and have compound combinations currently in testing. We anticipate data that will enhance our understanding further in Q1 2021.

Thanks for that, got myself registered.
There's alot of potential news flow over the next few months, will be interesting to hear this presentation.

Well the cars on hold, just took profits out of gdr and added another 10k worth here. The daily volume seems to be steadily climbing, something is going to happen soon people are taking positions. Get yourself ready.

No worries, someone else must of watched it and thought the same. Look at those late trades as gkb has pointed out. Wowzer.
I'm hoping my gdr go through the roof then can plunge in here with a decent holdings.

Bit odd you have just bought in then your first post is to say, 'should I be concerned'.
Why did you buy in the first place?

New information on this company as not many cover it. Hoping this will all change soon.
Sorry pressed post before I got to finish.

Haha nice.... He's going to be a very wealthy chap in the near future, money aswell as brains.
I will just have to do with my good looks.
You have to grab any bit of positive findings on this share as so hard to find

Well topped up with 5k worth. Wonder how long before it's spotted by the day traders.

Yeah Normally see them with smaller trades, they were large. Gutted didn't get chance to top up yet. Sods law, my largest holding sinks then my smallest takes off. Ffs.

Sorry forgot the link.

https://youtu.be/YdEbY6qC6BU

Financial not a problem we'll funded, and will continue to be with partners not dilution.
Found this on ig, interview from yesterday which expailns the buys and increase in volume.
Interesting from 16 mins on..
£100 mill deals not out of the question..

Something afoot volume is up.

It just makes a mockery of everything they say and tweet about how much interest they've had and how big the gaming market is open to all of this fantastic advertising space which they can sell, second half significantly heavy, but o were still in single figures.... Fu.... N joke.
Seeing my investment go from 150k to 75k in 2 days after being fed bullsh(!?.
Feel for everyone else too.

Have been told that interested party's wanting to advertise is through the roof or very much increased demand, then get this statement in the rns.
Bidstack has now run native in-game campaigns in over 30 countries. While this undoubtedly proves the system works, in 2020 fill rates for native in-game advertising remained in low single digits. As the Bidstack sales team matures there remains significant scope for organic growth.
Doea this mean there hasn't been much interest then and the sales teams can't do their job.?

This pandemic is said to go on for the next 2-3 years, plenty of time for large sales.
Never know what is around the corner too, have to say I'm ready for it all to be over tho.