RE: Inanaco16 Jul 2018 23:10
i refer you the first actual post i made. No criticism of RR at all ........
inanaco
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RE: CrukToday 09:03They are not evaluating ..........
Under the terms of the agreement, Scancell and BioNTech will enter into an initial research collaboration to discover and characterise T cell receptors specific for citrullinated epitopes from vimentin and enolase
Lindy has already explained the science of identification in the Feb Vid for Calculus.
BioNTech will have the exclusive option to enter into a licence agreement for the development of cell receptor based therapeutics that are specific to Modi-1 epitopes.
Its not up to scancell to develop TCR vaccines, as Lindy has already explained that they can identify down to the individual T cell that has gone active to the moditope epitope, Then the science of identifying and cloning out the TCR is BioNtechs.
As this is done in human blood not mice, scancell has shown that the moditope epitopes are immunogenic
otherwise you would not get an "activated t cell"
The fact that Genentech and BioNtech which are the drivers of TCR and have signed up to the Modi3 program subject to the grant is a clear indicator that the Modi1 TCR program is on track.