focusIR May 2024 Investor Webinar: Blue Whale, Kavango, Taseko Mines & CQS Natural Resources. Catch up with the webinar here.
Mologic are developing an antigen lateral flow device with ODX to manufacture it, who are part of the rapid test consortium.
Very little is known about this test, I would like to think we are ahead but we don't actually know for sure.
It appears Avacta will have more manufacturing capacity and that what will be the bottom line here (again, we don't know for sure but seems likely).
Trickymatter, whats your source to say the Mologic antigen LFA is further on than Avacta's test? What information is actually available on it as I'm struggling?
Yes, ANTIGEN tests, though.
Handjob is answering questions again this morning, this time on Radio 1 Xtra. May not be much to gather as Radio 1 newsbeat is the most condescending news program you can imagine where they believe all their listens are a bit thick. Could be worth a listen though - maybe he might even have his guard down a bit!
I may not be able to listen to it and they haven't said what time. If anybody can tune in and listen for any nuggets of info that would be good though!
Don't read into the number of minutes Phoenix. Handjob probably doesn't remember the amount of time for all the tests the Goverment are looking at/have looked at. Anything in under 30 mins would be an absolute game changer.
Tricky, thanks for your reply and explanation of antigen and antibody testing, very helpful....
Anyway - do you have links to any of these studies please?
There are mutated strains of sars-cov-2 (as is normal of course). What will happen if a different one because prevalent? Would you still have immunity?
It can't, but an antibody test may not be able to either. And even if the antibody test does confirm you've had it, immunity is a grey area so what are you planning to do with that information?
"It had been hoped that people who’d had COVID-19 might develop long-term immunity to further infection. However, studies looking at the levels of IgG antibodies, the type of antibodies that contribute to immunity, suggest this may not be the case.
Researchers studied 1,500 people admitted to hospitals in China with confirmed COVID-19 infection. These patients had antibody tests at least 21 days after admission. Almost 1 in 10 had no detectable IgG antibodies to the SARS-CoV-2 virus when tested. Another study of 37 people with a positive SARS-CoV-2 test but no symptoms, found that 40% had no detectable IgG antibodies two months after the infection."
And again:
"In the first longitudinal study of its kind, scientists analysed the immune response of more than 90 patients and healthcare workers at Guy’s and St Thomas’ NHS foundation trust and found levels of antibodies that can destroy the virus peaked about three weeks after the onset of symptoms then swiftly declined.
Blood tests revealed that while 60% of people marshalled a “potent” antibody response at the height of their battle with the virus, only 17% retained the same potency three months later. Antibody levels fell as much as 23-fold over the period. In some cases, they became undetectable."
And one more from the CDC
"Having antibodies to the virus that causes COVID-19 may provide protection from getting infected with the virus again. But even if it does, we do not know how much protection the antibodies may provide or how long this protection may last."
MU345, just to add - regular antigen testing is also capable of providing numbers of infections with sars-cov-2. I don't understand why people believe this can only be done with antibody testing?
Regulator UK, what's your source please as I would be interested to confirm?
"IgA is commonly seen as more immediate, and reflects antibodies along the mucosal membranes. IgA may appear after 3 days (some reports), but more likely after 10 days. Specificity of the IgA antibodies test is 87.5 – 100%"
IgM normally shows before IgG, however with sars-cov-2 the emerging evidence shows this may not be the case.
MU345 - Immunity is still a grey area and can't be relied upon. Although I agree that for stastical purposes it could be of use.
Sorry that was supposed to say
passed*
without quarantine*
What will antibody testing achieve though?
The most infectious stage is from 2 days before symtpoms show through to around 7 days afterwards. Antibody tests won't return positive until after the most infectious stage has already past.
Governments are looking for a test which will find those persons who are *most infectious.* Take note of those words as you're going to be hearing them a lot going forward IMO.
Immunity remains a grey area, but even if it's proven - special treatment can't be given. The problem being that if people with antibodies were given preferential treatment (lets say, going on holiday with quarantine), you would quickly get the adult equivilant of chicken pox parties and it sars-cov-2 would spread like wildfire. It would be a disaster.