Member Info for Energyshares

Greenwich LifeSciences

On his Twitter feed

This update from @avacta is hugely significant in targeted chemotherapy treatments for #Oncology. Successful delivery will save millions of lives per year and safe the #NHS billions!
First of its type in the UK!
Kill Cancer! #AVCT pre|CISION
A similar system introduced in the US recently on clinical approval took that companies share price from $5 US to $156 US just for Breast Cancer. But Avacta’s system could be used for many more existing #chemotherapy drugs across the whole of cancer treatments.

Foolnewbie
Drug patent expired,so any Pharma can copy as a generic.
I don’t think you will have to worry if it passes in human trial there will be a frenzy to buy Avacta between Big Pharma companies.

Adreco has won 2m award for tooling.
Has strong links to Mologic but also links to BBI.
It’s flip a coin time.

https://bidstats.uk/tenders/2020/W52/741408811

That’s my point they need to step up or jog on.

If we were in normal times, this would be headline news, but News channels are stuck at Dover.
Now it’s time for Yellow Jersey to step up and spread this news.

Good luck Tony
You have had faith in Avacta now they need to show faith in you.....

LSTM GATE
Kicking off now

Looks like LSTM to me

Dr Emily Adams, diagnostics lead at the Liverpool School of Tropical Medicine, explained to @BBCPM @EvanHD importance of tests to get freight traffic at Dover moving again.

Global health research (much done in UK) is vital for us all in so many ways @LSTMnews @FCDOResearch

FFS Lukeregan
A week out,what chance has Big Al with you being 8 months out.

To take overall responsibility for the operational management of the Rapid infection section of the department including Point of care and in-lab rapid testing.

In-Lab rapid testing that can’t be PCR with its 24 hour turn around.
Rapid Lab Ermmmm could be BAMS

£101m for a Testing hub based in Southampton....
https://bidstats.uk/tenders/?q=national+mass+testing+method#740622335-740491581-46

Manager New vacancy starts 1st week in Jan 2021
https://findajob.dwp.gov.uk/details/5080543
1st machine mentioned Bruker MALDI-TOF
Looking good for BAMS to be involved in this.

Avacta board meeting last week.
Al all the PI’s don’t like your waffle.
So we are going to give you options for your next interview.
Andrew Neil
Jeremy Paxman or Giles

Big Al pleaded for Neil or Paxman so he could get a easy ride.
But the board insisted on the Rottweiler Giles.

Tech transfer for September Q&A
I presume tech transfer from Cytiva to BBI.

But now Cytiva don’t seem to be in the picture anymore. Tech transfer is a in house procedure for BBI so would of been done in pilot batches.
Could be wrong ????

Until there are more vaccines available and they easier to administer, Infections will continue to multiply faster than vaccines can be rolled out.
The only way out of this Nightmare is to test, test , test with accurate LFD’s

Big Al knows this,so Avacta’s time will come early 2021 with the launch of the “Holy Grail”.

Today’s RNS
In addition, the Group has made excellent recent progress with its SARS-CoV-2 lateral flow rapid antigen test programme and we anticipate data from the first clinical trial soon.

Last time I heard test programme mentioned :
On 15 August 2020, DHSC Ministers commissioned PHE Porton Down to establish a time-limited SARS-CoV-2 test development and evaluation programme.

https://www.gov.uk/government/publications/assessment-and-procurement-of-coronavirus-covid-19-tests/protocol-for-evaluation-of-rapid-diagnostic-assays-for-specific-sars-cov-2-antigens-lateral-flow-devices

Big Al stop teasing and bloody tell us.

THIS SENTENCE SAYS IT ALL.
They can be used to selectively bind difficult targets, even where antibodies and aptamers have shown limitations.

Steve Burton, President of Astrea Bioseparations commented:

"Affimer reagents are high-performance proteinaceous ligands that have been engineered for a wide range of applications as superior alternatives to antibody-based ligands. They can be used to selectively bind difficult targets, even where antibodies and aptamers have shown limitations. In combination with our proven Mimetic Ligand® chemical ligand libraries, the Affimer ligand platform significantly expands our capacity to discover, develop and deliver custom affinity adsorbents for purification of biotherapeutics and advanced therapies."

Doh ,
Big Al has more Aces up his sleeves than Paul Daniels...
These Affimers are going to be so sought after in the next few years.

As part of the multi-target collaboration Avacta will generate and optimise Affimer® binders against three undisclosed cancer targets and provide these to ADC Therapeutics to target its proprietary cytotoxic warheads (PBDs) to the site of the tumour.

Look at this collaboration Avacta signed Oct 2019.
Combining Avacta’s Affimer® technology with ADC Therapeutics’ pyrrolobenzodiazepine (PBD)-based warhead and linker technologies.

https://avacta.com/collaboration-and-option-agreement-with-adc-therapeutics/

Now look at ADC Lead pipeline and LEAD CANDIDATE in phase 2

Lonca is an ADC composed of a humanized monoclonal antibody that binds to human CD19 and conjugated through a linker to a PBD-dimer toxin. Once bound to a CD19-expressing cell, Lonca is internalized into the cell where enzymes release the PBD-based warhead.

https://adctherapeutics.com/our-pipeline/

For a company with No products out yet.
They have enough fingers in many pies.

Tanner Pharma
This company just won 64 million contract
To supply Coronavirus Ag Rapid Test Cassettes.

Looked at their website but they are a very small company.
Does anyone think this could be the moulds for BBI standard test kit.

https://ted.europa.eu/udl?uri=TED:NOTICE:609022-2020:TEXT:EN:HTML&src=0