biomarkers downturn in US currently29 Apr 2020 09:18
Parsippany, New Jersey, 29 April 2020 - Diaceutics PLC, (AIM: DXRX), the precision diagnostic commercialization company, today announces research results from its COVID-19 oncology tracker, which shows the impact of the crisis on cancer testing and diagnosis in the US. The analysis, based on real-time data taken from the organization ' s data lake, shows that there has been a sharp downturn in both biomarker testing and cancer diagnosis rates between February and March of this year.
The figures, which have been tracked monthly since January 2019, provide an insight into the impact that COVID-19 and the subsequent lockdown measures being implemented across the United States are having on cancer patient care. Diaceutics found that compared to the month of February 2020, March saw a 31% drop in the number of patients being diagnosed with lung cancer. Testing rates for related biomarkers also decreased, with reductions ranging between 7% (KRAS) and 13% (EGFR). With regard to EGFR, Diaceutics estimates that there were nearly 4,000 fewer tests performed in March alone when compounding the reduced number of patients diagnosed and reduction in testing rates.
Diaceutics' COVID-19 oncology tracker also revealed a 14% drop in the number of new patients diagnosed with colorectal cancer during that same time period. The insights show that testing rates for biomarkers related to this form of cancer decreased as well. BRAF was down by 9%, while MSI/MMR was down by 8% and RAS was down by 6%. In the hematological setting, there was a 14% drop in newly-diagnosed patients with acute myeloid leukemia between February and March, with FLT3 (12%), IDH1 (11%) and IDH2 (12%) testing rates all dropping.
Diaceutics found that the number of newly-diagnosed breast cancer and ovarian cancer patients decreased by 8.4% and 8.6% respectively during this period.
The information upon which these findings are based is a representative dataset from Diaceutics ' data lake, which includes community, commercial and academic laboratories. Diaceutics defines newly-diagnosed cancer patients as those who have undergone a biopsy and surgical pathology testing and have not been recorded in the company's database previously.
Jordan Clark, CCO, Diaceutics, said: "These insights highlight the devastating impact that COVID-19 is having on cancer patients, from both a social distancing and healthcare system capacity viewpoint. Our research shows that laboratories are receiving fewer samples and hospitals are performing fewer biopsies. In fact, one community hospital laboratory reported that molecular oncology testing had slumped by 25%.
"Of course, the downturn in rates varies across the different types of cancer, with lung cancer being the worst affected. We suspect that this is because COVID-19 is a respiratory disease, so the symptoms that patients would normally consult their doctor about are potentially being mistaken for the novel coronavirus.
"On the other hand, in the case o
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