Member Info for crumbs

Scancell does have a paper about how antigen-specific T Regs may hinder effectiveness of the vax

'Modified antigens maybe a good target for anti-tumor immunity

but cancer patients have a specific LAP+ regulatory population

which would either need to be inhibited with a LAP/TGF-β

neutralizing antibody or polarized to Th1 with vaccination.'

https://www.scancell.co.uk/Data/Sites/1/media/publications/posters/paris-lap-poster.pdf

One thing is for sure, Team Scancell can Science the best out of the moditope platform... can they afford to though .... Needs ... always needed a partner

WTP writing was on the wall with the disaster RNS at first I think like yourself I read the positives in it only to begin seeing the negatives and when people pointed out what was missing modi 1 wise... bells rang and I took the action to save my capital... its that simple really and yes I then bought up a much smaller holding from the lows... I'm no trading genius I sat on 28p over 100% up when I shouldn't have ...But one thing was for certain I was never going to be sat underwater for what seemed like an eternity which happened after AGM of doom and decent to 3p ... you learn I guess..

So again this ought to be a bio unicorn why its failed to become one so far.... you tell me...

What I will say is to me and that is just me you can all make your own minds up! modi 1 is not looking commercial... that doesn't mean moditope is a write off but it needs work and work needs money

so... ImmunoBody and GlyMabs AvidiMab it is

TF it is up to Scancell to steady this ship I asked them ages agon after RNS disaster to do a Q&A presentation .... nowt

But they'll be in Milan talking the Science .. Is it too much to ask them to do both? whats the new CEO for

And you are my only friend :)

You can't read.... 30k in

Also here.. I think SCIB1 combo you won't know what that is... but anyways news coming on that I think it will be positive

I only think it though because for some reason this company prefers to present months old data to Scientific conferences than update its shareholder with clear up to date data...

so there you go a RAMP... plus the whole GlyMabs / AvidiMab are not priced in here at all.... whos fault is that though... certainly not shareholders!

This company ought to be a biotech unicorn £1 billion mcap

now do yourself a favour go read the Scancell website

Aha, a challenge for you do a write-up about modi 1 and its trial and how it is showing itself to be commercial... go on that will alter tomorrow for sure...

go find the missing data from the disater RNS where full dose mono patients vanished... explain how it is commercial in Ovarian mono where that part of the trial is over... tell us where the TNBC combo went...

You can be a force for good here you can get this to the PH2 trial paid for by erm..

Aha... you probably don't even know what a moditope is...

guess what Nothing anyone here says or does will alter the modi 1 trial results...

Some of that pattern is already in... if you can read RNS's.... if you think its looking commercial... go for it

Yeah I noticed that

From today

https://twitter.com/MkangoResources/status/1698635390754726062/photo/1

Seriously since EISHA approval made the MDA the next step so end of Jan

They aren't waiting for approval they are 'negotiating' a win-win....

I've got no friends :p and as has been said my position here changed with that sink of the SP RNS...my holding is crumbs sized it certainly was not me selling this down.... and guess what I've bought none either ....no idea what or when the next RNS will be beyond new Business manager expected and CIMT ought to have some positives... thats it... no idea if GenMab are going to pay anything more no idea if there will ever be another deal on anything ever... same as everyone else... If I were a master trader I'd have sold at 28p!!!!!

BTW maybe can see why LD didn't bother paying for her options and been no Diggle wiggle and no idea did RG sell a big chunk either ... but if it makes you feel better bashing someone who's holding went down from over 300k to 30k with some shuffling to get the average right down and not lose a shedload... as today shows real volatile this.. why?... go for it lol I'm fine with it... over to you wishing you well with how you decide to play this... it does indeed have many strings to the bow so if it comes good I'll be well happy and if it don't oh well...

At end of day I couldn't buy anything unless on negotiated order....let's hope it's a good sign

Accept a thanks for the heads up crumbs as that news is out there and you'd be hearing it at some point....Do you think I'm happy that modi 1 is not having the mouse result effect on patients we know of ? No I want it to be complete game changer and yes it still can be ...over to Lindy and team scancell science now...what each of you do shares wise is up to you you are mostly adults 😏....

What rubbish? It's information from a patient forum again do with it as you wish ....not all treatments work

The saddest thing is for the patients ...Hopefully, Modi 1 does still find a niche from what we know 1 patient in the Combo cohort has had tumor reduction and one we know of the McMillan poster has had no obvious effect ....

Would be good to have more regular data readouts from Scancell like we thought we were going to be getting

No, I'm just letting everyone know... what you all do with the info is up to you

SCIB1 combo is probably doing great though they have kept that data under wraps for a long time....

The other patient is on the CI combo... no effecr

Fully doses both of them

Trish is no longer on Modi 1 tumour growing though it did initially shrink it significantly and another patient there on CI combo part of the trial had no effect so far at all on her Renal cancer