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Hi Krone, interesting statement from that article...
As clinicians and researchers attempt to figure out the sweet spot of who exactly benefits the most from convalescent plasma, all the experts agreed that former FDA commissioner Steve Hahn’s early mistakes in characterizing convalescent plasma as a “historic breakthrough” and mischaracterizing the relative versus absolute benefit of plasma have lingered in the public’s mind.
“That poisoned the well in some ways,” Casadevall said, referring to Hahn’s press conference announcing the plasma EUA. He said he encourages physicians to take a look at the “mosaic of data out there,” and the totality of the data, especially as there are other negative trials for some Covid-19 drugs like Gilead’s remdesivir too, which is still used widely.
Bodes well for our wee little Sareum ;)
What our 1801 is targeting, and you don't need a phd to understand it ;)
https://www.news-medical.net/news/20210818/Severe-COVID-19-characterized-by-phosphorylation-of-STAT1.aspx
Stay buckled in, the route to CT is what will make Sareum's share price orbit, and we know the RNS will drop once they've had their chit chat with the experts ;)
Trading Statement as expected, no dramas, time to get cheap shares if your not loaded already...
Interesting read, if not for Covid, then definitely an option for Cancer
https://www.clinicaltrialsarena.com/uncategorized/significant-increase-virtual-trial-2020-covid-19/
Scary thing is the waiting, which ever way Sareum take 1801 forward will be a white knuckle ride, guaranteed , release shares with gratitude or hold for the fortune, whatever you choose, don't be greedy, be happy ;)
https://www.youtube.com/watch?v=d-diB65scQU
https://www.who.int/news/item/11-08-2021-who-s-solidarity-clinical-trial-enters-a-new-phase-with-three-new-candidate-drugs
blurry eyed, heres the link ;)
Just pondering, while were waiting patiently with HWNI's jumping on board in an orderly manner;) could we be actually heading world wide instantly? (yes the world would hear soon;) )
Well rather than Agile, WHO would prefer WHO's route to clinical trials?
https://www.lse.co.uk/ShareChat.asp?ShareTicker=SAR&share=Sareum&thread=90FD7C31-4B2C-4C41-8A3B-FD9635EE8AC2&reply=true
The Solidarity PLUS trial is a platform trial that represents the largest global collaboration among WHO Member States. It involves thousands of researchers in over 600 hospitals in 52 countries, 16 more countries than the first phase of trials. This allows the trial to assess multiple treatments at the same time using a single protocol, recruiting thousands of patients to generate robust estimates on the effect a drug may have on mortality--even moderate effects.
It also allows new treatments to be added and ineffective treatments to be dropped throughout the course of the trial.
World wide instantly... come on Sareum, practice what ya preach, ya peach ;)
Am I dreaming again?? The Solidarity PLUS trial, £1 don't blink
GLALTH's, set your targets ;)
https://endpts.com/a-rip1-contender-fails-to-make-the-cut-at-gsk-after-a-fast-fizzle-in-pancreatic-cancer/
no messing around...
GSK must be eying up Sareum big time ;)
Another Great post Citizen, from that article
The next batch of targets that may bear fruit in lupus treatment are cytokines such as interleukin-10, IL-6, IL-21, IL-2 restoration, IL-12/23 and the janus kinase (JAK)/ signal transducer and activator of transcription (STAT) signaling pathway. “There are a lot of potential cytokines to target,” Furie said.
Furie showed particular interest in IL-2. “Patients with lupus are relatively deficient in IL-2 production,” he said.
Upstream from the JAK/STAT pathway is TYK2, which is targeted by baricitinib, according to Furie. “There is a lot of excitement about TYK2 inhibitors,” he said.
Its been a fantastic journey T2, wont be long before the big news drops, lets keep our fingers crossed Sareum's molecules are the real deal. I really do wish the the very best in you voyages, carnal pleasures and giant Wotsits ;)
somewhere to keep your yacht's .. ;) ;)
https://www.boatinternational.com/luxury-yacht-life/property/best-private-islands-for-sale--31861
All in all I think all our LTH's are in a very good position, most on a free ride ;)
so lets chill and enjoy the ups downs, side slides and fast rides.
Follow your instinks, if it stinks (SRRA) keep away from it.
All good with Sareum, just need the T's crossed and I's dotted, everything else has already aligned ;)
and now there's another virus...
Ebola-like Marburg virus
https://www.msn.com/en-gb/health/medical/more-than-150-people-in-isolation-as-health-authorities-race-to-contain-ebola-like-marburg-virus/ar-AANc8q5?ocid=entnewsntp
if 1801 works against Covid, WHO knows how many other virus's it could deal with..
https://www.msn.com/en-gb/news/coronavirus/covid-news-live-hospitals-declare-black-alerts-as-uk-records-104-further-deaths/ar-AANaTYf?ocid=entnewsntp
Cuba, Melbourne...
I'm honored to be a holder of Sareum shares, now lets kick Covid arse ;)