RE: Sunday Times8 Mar 2020 08:31
Coronavirus vaccine race: volunteers to be infected in the UK
Human guinea pigs in a London lab are to be given a form of the killer virus as the search for a lucrative jab hots up
Hospital medics in Wuhan, China: human testing of prototype vaccines could begin next month
Hospital medics in Wuhan, China: human testing of prototype vaccines could begin next month
STR/AFP/GETTY
Sabah Meddings
Sunday March 08 2020, 12.01am, The Sunday Times
It sounds tempting: a payment of £3,500 to spend two weeks relaxing in front of the television, playing video games or catching up on some reading. There is a catch, however — you will be infected with a coronavirus and banned from physical contact with the outside world.
As part of a global experiment, up to 24 people at a time will be paid to be infected with a coronavirus in a $2bn (£1.53bn) race to find a vaccine for Covid-19.
Hvivo, the company that runs the quarantine unit in a laboratory in east London, is one of more than 20 firms and public sector organisations taking part in a global effort to develop a vaccine for the virus, which has killed more than 3,500 people. The aim is to have an injection that could be used next winter to protect the elderly and those with underlying health conditions.
In America, the Coalition for Epidemic Preparedness Innovations (Cepi) is sponsoring four vaccine projects, including one by Moderna, a biotech company based outside Boston. British drug giants such as Glaxo Smith Kline — which has teamed up with Clover Biopharmaceuticals, a Chinese biotech firm — have also committed to researching a vaccine. The World Health Organisation said there were more than 20 in development.
The rewards are considerable. The French drugmaker Sanofi, one of the world’s biggest producers of vaccines, made €1.9bn (£1.6bn) selling vaccines against flu last year. The rewards for an effective coronavirus vaccine could be considerably higher.
Professor John Oxford, an expert in virology at Queen Mary University of London, has studied cold and flu viruses, including coronavirus, for more than 50 years. He said a vaccine was “at least a year away”. However, several labs have prototypes they are testing on animals, and human trials are due to begin next month.
Play Video
Inside the lab trying to create a coronavirus vaccine
Work on a vaccine to protect against Covid-19 began in January, when Chinese researchers released the genetic data for the virus, prompting the worldwide effort. Cepi, which was set up in response to the ebola outbreaks of 2014-2016, is a crucial aid in funding development of a vaccine, which the organisation’s chief executive, Richard Hatchett, estimates could cost $2bn.
However, experts have suggested that the UK risks being unable to secure supplies of vaccines because it does not have the production capability to manufacture its own. Instead, Britain will have to rely on imports from overseas.
Part of the problem is investment. While the gove