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Tiziana Life Sciences Begins First-In-Human Phase 1 Trial Of Foralumab

Wed, 28th Nov 2018 12:19

LONDON (Alliance News) - Tiziana Life Sciences PLC on Wednesday said it began the first in-human trial of Foralumab, a treatment for autoimmune diseases.

The biotechnology company said the product will be tested in healthy volunteers through nasal administration.

The choice of administering the product via intranasal delivery is a "first and major milestone towards the company's objective to develop innovative therapies with alternative routes of administration whilst maximizing efficacy", Tiziana explained.

The phase 1 trial aims to evaluate the safety and tolerability of Foralumab.

"The clinical protocol also includes evaluation of unique biomarkers of immunomodulation, induction of T regulatory cells and anti-inflammation to assess therapeutic potential of the treatment," Tiziana explained.

Tiziana shares were trading down 4.8% around midday on Wednesday at 74.50 pence each.

More News
7 Feb 2019 11:40

Tiziana Life Sciences Non-Exec Director Riccardo Dalla-Favera Resigns

LONDON (Alliance News) - Tiziana Life Sciences PLC on Thursday said Non-Executive Director Riccardo Dalla-Favera has resigned from his role."The company is grateful to Favera for his

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3 Dec 2018 14:27

Tiziana completes patient enrolment in ongoing Milciclib study

(Sharecast News) - Biotechnology company Tiziana Life Sciences announced on Monday that patient enrolment in its ongoing Phase 2a clinical trial, known as CDKO-125A-010, was now completed.

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3 Dec 2018 11:51

Tiziana Life Completes Patient Enrollment In Liver Cancer Trial

LONDON (Alliance News) - Tiziana Life Sciences PLC on Monday said it completed patient enrollment in a Phase 2a trial of Milciclib in hepatocellular carcinoma.The company explained that the

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20 Nov 2018 12:53

Tiziana Life Sciences Prices ADS Offering, Raises GBP3.4 Million

LONDON (Alliance News) - Tiziana Life Sciences PLC said Tuesday that it has priced its underwritten public offering in the US of 442,910 American Depositary Shares representing ordinary shares in

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25 Sep 2018 13:43

Tiziana Life Seeks Listing Of ADS On Nasdaq Capital Market (ALLIPO)

LONDON (Alliance News) - Tiziana Life Sciences PLC said Tuesday that it has commenced underwritten public offering in the US of American Depositary Shares representing ordinary shares in the UK of

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24 Sep 2018 12:37

Tiziana Half-Year Loss Unchanged; Gets US Approval For Foralumab Trial

LONDON (Alliance News) - Tiziana Life Sciences PLC on Monday reported a flat loss in the first half of 2018 as expenses were broadly unchanged, while the biotechnology firm also announced that its

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17 Aug 2018 11:39

DIRECTOR DEALINGS: Tiziana Life Chairman Associate Buys Shares

LONDON (Alliance News) - Tiziana Life Sciences PLC said Friday that Panetta Partners Ltd, a company associated with Chairman Gabriele Cerrone, bought shares in the company worth acquired 469,766 a

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16 Aug 2018 11:47

Tiziana seeks trial for multiple sclerosis 'game changer'

(Sharecast News) - Tiziana Life Sciences on Thursday submitted an application to initiate phase one clinical trials for a new treatment of neurodegenerative diseases to the US food and drug administration.

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27 Jul 2018 11:14

Tiziana Life Sciences Files For IPO Of American Depositary Shares (ALLIPO)

LONDON (Alliance News) - Tiziana Life Sciences PLC said Friday it filed a registration statement with the US Securities Exchange Commission for a proposed initial public offering of its American

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16 May 2018 13:27

Tiziana Life Science Reports Progress In Milcicib Phase 2a Trial

LONDON (Alliance News) - Biotechnology company Tiziana Life Sciences PLC said Wednesday that the phase 2a trial of Milciclib safety and tolerability in patients with Metastatic Hepatocellular has

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19 Apr 2018 14:44

Tiziana Raises GBP825,000 Through Placing Of 1 Million Shares (ALLISS)

LONDON (Alliance News) - Tiziana Life Sciences PLC said Thursday it has raised GBP825,000 from the issue of 1.0 million new shares at a price of 80 pence per share.The cancer and autoimmune

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4 Apr 2018 12:53

Tiziana Appoints Leopoldo Zambeletti As Non-Executive Director

LONDON (Alliance News) - Tiziana Life Sciences PLC, a biotechnology company developing drugs for cancer and autoimmune diseases, said Wednesday Leopoldo Zambeletti has joined

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16 Nov 2016 09:34

Tiziana Life Sciences makes breakthrough oral treatment for inflammatory diseases

(ShareCast News) - Tiziana Life Sciences, the clinical stage biotechnology company, announced that new data has demonstrated the potential of its novel oral therapy with foralumab for non-alcoholic steatohepatitis (NASH), diabetes and other life threatening inflammatory diseases. Oral efficacy in hu

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18 Jul 2016 12:03

Tiziana Life looks for secrets of long life with new acquisition

(ShareCast News) - Tiziana Life Sciences has purchased key assets from Sardinia-based biobanking and genomics research company Shardna for €258,000, giving it access to the genetic data of nearly 13,000 people from the Ogliastra region, where life expectancy is high. The AIM-listed clinical stage bi

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